Development Level

Tbio 14 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased circulating serum al... 2 | 82
increased circulating LDL chol... 2 | 13
abnormal brain morphology 1 | 13
abnormal limb morphology 1 | 13
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hydroencephaly 1 | 14
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
respiratory system phenotype 1 | 2

Disease

Carcinoma 16 | 11,493
medulloblastoma, large-cell 16 | 6,241
glioblastoma 12 | 5,792
ovarian cancer 12 | 8,520
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
osteosarcoma 10 | 7,950
Schizophrenia 9 | 1,160
ependymoma 9 | 4,679
group 3 medulloblastoma 9 | 4,104
primitive neuroectodermal tumor 9 | 3,035
psoriasis 9 | 6,694
Astrocytoma, Pilocytic 8 | 3,081
interstitial cystitis 8 | 2,312
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
Autistic Disorder 7 | 364
Cancer 7 | 2,499
Kidney cancer 7 | 2,613
astrocytic glioma 7 | 2,597
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
pituitary cancer 7 | 1,972
Bipolar Disorder 6 | 666
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
juvenile dermatomyositis 6 | 1,187
tuberculosis 6 | 2,010
Breast cancer 5 | 3,578
Intellectual disability 5 | 1,016
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Down syndrome 4 | 499
Epilepsy 4 | 792
Kidney disease 4 | 430
Seizures 4 | 596
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Breast Neoplasms 3 | 445
Cerebral atrophy 3 | 178
Cognition Disorders 3 | 32
Dementia 3 | 175
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Heart disease 3 | 306
Lung Neoplasms 3 | 232
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Multiple myeloma 3 | 1,332
Neurodegenerative disease 3 | 414
Parkinsonian Disorders 3 | 56
Thrombocytopenia 3 | 197
Toxic encephalopathy 3 | 141
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
hearing impairment 3 | 199
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Adult onset 2 | 82
Alzheimer Disease 2 | 83
Anemia 2 | 365
Atopic dermatitis 2 | 952
Cardiovascular system disease 2 | 246
Cerebrovascular disease 2 | 238
Congenital deafness 2 | 185
Curvature of spine 2 | 282
Deafness 2 | 198
Diarrhea 2 | 253
Dysarthria 2 | 192
Fragile X syndrome 2 | 34
Gastroesophageal reflux disease 2 | 110
Hearing Loss, Partial 2 | 185
Heartburn 2 | 78
Hypertension 2 | 396
Leishmaniasis 2 | 47
Leukopenia 2 | 72
Liver Cirrhosis 2 | 181
Movement Disorders 2 | 55
Multiple Sclerosis 2 | 540
Neoplasm Invasiveness 2 | 161
Neuropathy 2 | 261
Parkinson's disease 2 | 392
Unipolar Depression 2 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
dermatomyositis 2 | 966
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Endocrine System 20 | 18,159
Nervous System 20 | 16,725
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192
Respiratory system 19 | 16,393

Target Family

Non-IDG 10 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Epigenetic 2 | 242
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

positive regulation of dendrit... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein LLP homolog LLPH Tdark Non-IDG -0.64345 4.17 70
Forkhead box protein O6 FOXO6 Tbio Transcription Factor -1.13890 17.2 38
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.34679 21.2 88
Protein EURL homolog C21orf91 Tbio Non-IDG -1.66118 45.2 66
Neurabin-1 PPP1R9A Tbio Non-IDG -1.00329 12.4 117
Interleukin-2 IL2 Tchem Non-IDG -4.37903 24027.6 1518
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Calcium/calmodulin-dependent protein kinase type 1 CAMK1 Tchem Kinase -1.58278 39.5 219
Disks large homolog 5 DLG5 Tbio Non-IDG -1.71553 56.2 60