Development Level

Tbio 23 | 11,651
Tchem 7 | 1,388
Tclin 3 | 612
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Targets) 3 | 126

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
abnormal cranium morphology 1 | 36
abnormal retina morphology 1 | 71
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating unsatura... 1 | 2
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 26 | 11,493
ovarian cancer 15 | 8,520
group 3 medulloblastoma 13 | 4,104
lung cancer 13 | 4,740
medulloblastoma, large-cell 13 | 6,241
Breast cancer 12 | 3,578
Cancer 12 | 2,499
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
osteosarcoma 12 | 7,950
primitive neuroectodermal tumor 12 | 3,035
adrenocortical carcinoma 11 | 1,428
ependymoma 10 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
psoriasis 10 | 6,694
Kidney cancer 9 | 2,613
adult high grade glioma 9 | 3,801
malignant mesothelioma 9 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
Atopic dermatitis 7 | 952
Endometriosis 7 | 540
lung adenocarcinoma 7 | 2,716
Astrocytoma, Pilocytic 6 | 3,081
invasive ductal carcinoma 6 | 2,951
nasopharyngeal carcinoma 6 | 1,058
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
astrocytic glioma 5 | 2,597
colon cancer 5 | 1,478
lung carcinoma 5 | 2,843
Bipolar Disorder 4 | 666
Parkinson's disease 4 | 392
Pick disease 4 | 1,894
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
Autosomal recessive predisposition 3 | 1,442
Crohn's disease 3 | 321
Depressive disorder 3 | 409
Hypertension 3 | 396
Major Depressive Disorder 3 | 301
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Nystagmus 3 | 317
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Small head 3 | 374
Unipolar Depression 3 | 250
active Crohn's disease 3 | 922
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Abnormality of retinal pigmentation 2 | 111
Acromegaly 2 | 51
Adenoma 2 | 167
Alcoholic Intoxication, Chronic 2 | 289
Amphetamine-Related Disorders 2 | 74
Attention deficit hyperactivity disorder 2 | 278
Blindness 2 | 88
Cocaine-Related Disorders 2 | 92
Cognition Disorders 2 | 32
Difficulties with night vision 2 | 87
Disruptive, Impulse Control, and Conduct Disorders 2 | 3
Dyskinesia, Drug-Induced 2 | 15
Gastroesophageal reflux disease 2 | 110
Hyperactive behavior 2 | 91
Hyperalgesia 2 | 83
Hyperreflexia 2 | 209
Liver cancer 2 | 604
Low Vision 2 | 174
Mental Depression 2 | 333
Mood Disorders 2 | 184
Movement Disorders 2 | 55
Myopia 2 | 176
Nausea and vomiting 2 | 97
Neurodegenerative disease 2 | 414
Neurodevelopmental Disorders 2 | 70
Night Blindness 2 | 101
Pathological gambling 2 | 15
Photodysphoria 2 | 121
Photophobia 2 | 121
Pituitary adenoma 2 | 38
Polycystic ovary syndrome 2 | 360
Retinal pigment epithelial abnormality 2 | 111
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Substance-Related Disorders 2 | 115
Urticaria 2 | 67
Visual Impairment 2 | 174
acute quadriplegic myopathy 2 | 1,158
cystic fibrosis and chronic rhinosinusitis 2 | 214
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962

Tissue

Endocrine System 31 | 18,159
Digestive Tract 29 | 17,369
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Urinary Tract 27 | 16,678
Cardiovascular System 26 | 15,192
Female tissues 26 | 17,400
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Blood and immune system 25 | 16,909

Target Family

Non-IDG 14 | 12,091
GPCR 10 | 408
Kinase 5 | 634
Enzyme 4 | 4,145
oGPCR 2 | 421

GO Process

positive regulation of cytokin... 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Long-wave-sensitive opsin 1 OPN1LW Tbio GPCR -2.37983 238.7 47
Medium-wave-sensitive opsin 1 OPN1MW Tbio GPCR -0.97721 8.41 18
Mas-related G-protein coupled receptor member X2 MRGPRX2 Tbio GPCR -1.54925 35.2 193
Olfactory receptor 1A2 OR1A2 Tdark oGPCR -0.35218 1.89 21
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.37859 20.9 98
Cullin-3 CUL3 Tbio Non-IDG -3.26322 1670.8 307
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501
Rac GTPase-activating protein 1 RACGAP1 Tbio Enzyme -1.69445 57.6 382