Development Level

Tbio 30 | 11,445
Tchem 12 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
aorta stenosis 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased B cell number 1 | 5
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased IgG2b level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased circulating bilirubi... 1 | 16
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
premature death 1 | 5
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

ovarian cancer 32 | 8,520
Cancer 27 | 2,499
Carcinoma 26 | 11,493
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 20 | 6,241
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
psoriasis 18 | 6,694
atypical teratoid / rhabdoid tumor 17 | 5,112
ependymoma 16 | 4,679
malignant mesothelioma 16 | 3,232
lung carcinoma 13 | 2,843
Breast cancer 12 | 3,578
Astrocytoma, Pilocytic 11 | 3,081
invasive ductal carcinoma 11 | 2,951
non-small cell lung cancer 11 | 2,890
pancreatic cancer 11 | 2,398
adrenocortical carcinoma 10 | 1,428
astrocytic glioma 10 | 2,597
cystic fibrosis 10 | 1,696
diabetes mellitus 10 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung adenocarcinoma 10 | 2,716
primitive neuroectodermal tumor 10 | 3,035
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
oligodendroglioma 9 | 2,850
primary pancreatic ductal adenocarcinoma 9 | 1,109
ulcerative colitis 9 | 1,819
Liver Cirrhosis, Experimental 8 | 769
Multiple myeloma 8 | 1,332
adult high grade glioma 8 | 3,801
pediatric high grade glioma 8 | 1,064
ductal carcinoma in situ 7 | 1,745
pituitary cancer 7 | 1,972
Arthritis 6 | 290
Bipolar Disorder 6 | 666
Kidney cancer 6 | 2,613
Lung Neoplasms 6 | 232
Obesity 6 | 678
Rheumatoid arthritis 6 | 1,191
juvenile dermatomyositis 6 | 1,187
subependymal giant cell astrocytoma 6 | 2,287
Adenocarcinoma 5 | 122
Atherosclerosis 5 | 291
Carcinoma, Hepatocellular 5 | 228
Inflammation 5 | 120
Kidney disease 5 | 430
Liver carcinoma 5 | 240
Multiple Sclerosis 5 | 540
Neoplasm Metastasis 5 | 168
Parkinson's disease 5 | 392
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
Stomach Neoplasms 5 | 300
Vascular disease 5 | 319
Waldenstrons macroglobulinemia 5 | 765
active ulcerative colitis 5 | 764
cutaneous lupus erythematosus 5 | 1,057
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
spina bifida 5 | 1,074
tuberculosis 5 | 2,010
Alzheimer's disease 4 | 658
Breast Neoplasms 4 | 445
Chronic Lymphocytic Leukemia 4 | 262
Colorectal Neoplasms 4 | 243
Epilepsy 4 | 792
Fatty Liver 4 | 70
Hypersensitivity reaction type II disease 4 | 253
Mammary Neoplasms 4 | 425
Melanoma 4 | 711
Muckle-Wells syndrome 4 | 12
Myocardial Infarction 4 | 151
Neurodegenerative disease 4 | 414
Peritonitis 4 | 43
Pick disease 4 | 1,894
Pneumonia 4 | 174
Polycystic ovary syndrome 4 | 360
Pulmonary Fibrosis 4 | 106
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
gastric cancer 4 | 459
group 4 medulloblastoma 4 | 1,855
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
sarcoidosis 4 | 370
Atopic dermatitis 3 | 952
Depressive disorder 3 | 409
Diabetes Mellitus, Type 2 3 | 142
Mental Depression 3 | 333
Seizures 3 | 596
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
hepatocellular carcinoma 3 | 547

Tissue

Female tissues 44 | 17,400
Male tissues 44 | 17,142
Skin and soft tissues 44 | 17,230
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Blood and immune system 42 | 16,909
Liver and Pancreas 42 | 16,750
Urinary Tract 42 | 16,678
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 7 | 4,145
Transcription Factor 7 | 1,400
Kinase 3 | 634
GPCR 2 | 408
Epigenetic 1 | 242

GO Process

positive regulation of cystein... 46 | 46
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.82146 68.5 245
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.60032 392.5 519
Transcription factor SOX-7 SOX7 Tbio Transcription Factor -1.69107 35.6 169
Protein CASC2, isoform 3 CASC2 Tbio Non-IDG 0.00000 0
B-cell receptor-associated protein 31 BCAP31 Tbio Non-IDG -1.70781 57.4 398
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453