Development Level

Tchem 4 | 1,598
Tbio 3 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
corneal opacity 1 | 32
decreased circulating alkaline... 1 | 46
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
Breast cancer 5 | 3,578
Cancer 5 | 2,499
Kidney cancer 5 | 2,613
lung cancer 5 | 4,740
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
breast carcinoma 4 | 1,638
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
Alzheimer's disease 3 | 658
Autosomal recessive polycystic kidney disease 3 | 41
Disease Models, Animal 3 | 155
Kidney disease 3 | 430
Lung disease 3 | 142
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
osteosarcoma 3 | 7,950
Adenoma 2 | 167
Adenomatous Polyposis Coli 2 | 16
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal dominant polycystic kidney disease 2 | 31
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Squamous Cell 2 | 110
Colon diverticulum anatomic structure 2 | 15
Colorectal Neoplasms 2 | 243
Congenital diaphragmatic hernia 2 | 67
Corneal Ulcer 2 | 21
Dacryocystitis 2 | 11
Diverticular disease of colon 2 | 15
Downward slant of palpebral fissure 2 | 158
Familial adenomatous polyposis 2 | 32
Immune system cancer 2 | 140
Inflammatory bowel disease 2 | 151
Kidney Failure 2 | 111
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Marijuana Abuse 2 | 31
Orbital separation excessive 2 | 244
Ovarian Neoplasms 2 | 102
Papilloma 2 | 44
Papule 2 | 43
Pimples 2 | 10
Polycystic Kidney - body part 2 | 18
Polycystic Kidney Diseases 2 | 20
Polycystic Kidney, Autosomal Dominant 2 | 7
Polycystic liver disease 2 | 16
Precancerous Conditions 2 | 80
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Skin cancer 2 | 469
Squamous cell carcinoma 2 | 129
Stomach Neoplasms 2 | 300
Thyroiditis 2 | 29
adult high grade glioma 2 | 3,801
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
ovarian neoplasm 2 | 99
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
pustule 2 | 10
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abnormality of the penis 1 | 7
Alcohol abuse 1 | 50
Broad hallux 1 | 29
Conjunctival hamartoma 1 | 7
Cowden disease 1 | 18
Fibrous skin tumor of tuberous sclerosis 1 | 18
Gastrointestinal hamartomatous polyps 1 | 10
Hamartoma Syndrome, Multiple 1 | 10
Hamartomatous polyp 1 | 10
Hyperkeratosis, generalized 1 | 14
Intestinal atresia 1 | 12
Macule 1 | 19
Mucosal telangiectasiae 1 | 14
Multiple, subcutaneous nodules 1 | 53
Polycystic kidney disease, type 2 1 | 1
Polyp of large intestine 1 | 8
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
Thyroid Gland Follicular Adenoma 1 | 9

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Kinase 3 | 634
Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344

GO Process

positive regulation of cyclin-... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Polycystin-1 PKD1 Tbio Non-IDG -2.60276 379.9 123
Disintegrin and metalloproteinase domain-containing protein 17 ADAM17 Tchem Enzyme -3.55216 3569.0 718
Serine/threonine-protein kinase pim-1 PIM1 Tchem Kinase -2.87679 758.8 531
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Regulator of cell cycle RGCC RGCC Tbio Non-IDG -2.32382 150.8 54
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565