Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased heart weight 1 | 27
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased total retina thickne... 1 | 4
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Epilepsy 3 | 792
Hepatomegaly 3 | 285
Seizures 3 | 596
pancreatic cancer 3 | 2,398
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Cognitive delay 2 | 608
Deglutition Disorders 2 | 132
Dull intelligence 2 | 645
Dystonia 2 | 164
Dystonic disease 2 | 106
Elevated hepatic transaminases 2 | 81
Global developmental delay 2 | 608
Hepatic enzyme increased 2 | 81
Intellectual disability 2 | 1,016
Lipid metabolism disorder 2 | 114
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Neonatal Hypotonia 2 | 64
Obesity 2 | 678
Poor school performance 2 | 645
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Abnormal urinary amino-acid findings 1 | 38
Abnormal visual evoked potential 1 | 26
Abnormality of metabolism/homeostasis 1 | 134
Adrenoleukodystrophy 1 | 29
Alkaline phosphatase serum increased 1 | 29
Aminoaciduria 1 | 38
Ataxia 1 | 15
Central nervous system demyelination 1 | 28
Chemical and Drug Induced Liver Injury 1 | 195
Comatose 1 | 56
Death in early childhood 1 | 82
Death in infancy 1 | 82
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Elevated heart rate 1 | 25
Familial adenomatous polyposis 1 | 32
Fasting Hypoglycemia 1 | 8
Fatigue 1 | 182
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Gangliosidosis 1 | 20
Gastrointestinal Stromal Tumors 1 | 48
Gaucher disease type 1 1 | 180
Global developmental delay, severe 1 | 47
Hyperhidrosis disorder 1 | 81
Hyperinsulinism 1 | 133
Hypodontia 1 | 81
Increased calcium level in kidney 1 | 21
Increased sweating 1 | 81
Lethargy 1 | 77
Leukodystrophy 1 | 55
Liver diseases 1 | 87
Loss of speech 1 | 16
Metabolic syndrome X 1 | 52
Neonatal hypoglycemia 1 | 17
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Ophthalmoplegia 1 | 106
Pallor 1 | 40
Progressive mental retardation 1 | 37
Progressive neurologic deterioration 1 | 19
Respiratory function loss 1 | 121
Rickets 1 | 49
Sensorineural Hearing Loss (disorder) 1 | 284
Severe psychomotor retardation 1 | 47
Sweating 1 | 81
Tremor 1 | 113
Zellweger syndrome 1 | 37
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
maturity-onset diabetes of the young 1 | 32

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 2 | 12,091
Nuclear Receptor 2 | 48
Enzyme 1 | 4,145

GO Process

positive regulation of cholest... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 Tbio Enzyme -2.10178 116.1 292
Hepatocyte nuclear factor 4-alpha HNF4A Tchem Nuclear Receptor -3.19918 1373.3 664
Protein transport protein Sec24A SEC24A Tbio Non-IDG -0.75034 4.05 79
Oxysterols receptor LXR-alpha NR1H3 Tchem Nuclear Receptor -2.19201 123.0 390