Development Level

Tbio 4 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80

Disease

Carcinoma 4 | 11,493
Cancer 2 | 2,499
Congenital heart disease 2 | 93
Down syndrome 2 | 499
Failure to gain weight 2 | 365
Hydrocephalus 2 | 152
Pediatric failure to thrive 2 | 365
lung cancer 2 | 4,740
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
11 pairs of ribs 1 | 7
46, XX Testicular Disorders of Sex Development 1 | 3
46,XY partial gonadal dysgenesis 1 | 9
46,Xx Sex Reversal 1 1 | 3
ANONYCHIA 1 | 20
Abnormal scrotal rugation 1 | 2
Abnormal sex determination 1 | 11
Abnormality of male internal genitalia 1 | 4
Abnormality of the labia 1 | 9
Abnormality of the metacarpal bones 1 | 17
Abnormality of the pharynx 1 | 19
Abnormality of the scrotum 1 | 9
Absent bone maturation in sternum 1 | 4
Absent sternal ossification 1 | 4
Adams-Oliver syndrome 1 | 15
Alagille syndrome 1 | 15
Ambiguous Genitalia 1 | 24
Anonychia congenita 1 | 2
Anterior bowing of tibia 1 | 1
Aplasia Cutis Congenita 1 | 14
Autism Spectrum Disorders 1 | 75
Bifid scrotum 1 | 16
Cadasil 1 | 10
Calvarial defect 1 | 10
Campomelic dysplasia 1 | 7
Claw hand 1 | 26
Congenital Hand Deformities 1 | 8
Congenital atresia of pulmonary artery 1 | 5
Congenital scar 1 | 13
Cranial defect 1 | 10
Cutis marmorata 1 | 32
Decreased fertility 1 | 33
Decreased fertility in females 1 | 20
Decreased testosterone in males 1 | 28
Degenerative disc disease 1 | 35
Delayed Puberty 1 | 97
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Female external genitalia in males 1 | 13
Femoral bowing 1 | 20
Glossoptosis 1 | 10
Gonadal Dysgenesis 1 | 28
Gonadal Dysgenesis, Mixed 1 | 19
Gynecomastia 1 | 64
Hand Deformities, Congenital 1 | 8
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypoplasia of scrotum 1 | 24
Hypoplasia of vagina 1 | 14
Hypoplastic cervical vertebrae 1 | 3
Hypoplastic iliac wing 1 | 19
Hypoplastic inferior ilia 1 | 3
Hypoplastic scapulae 1 | 14
Kyphoscoliosis deformity of spine 1 | 60
Laryngomalacia 1 | 14
Low serum estradiol levels 1 | 22
Ovotesticular Disorders of Sex Development 1 | 2
Pierre Robin Syndrome 1 | 11
Posterior displacement of the tongue 1 | 10
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Pure gonadal dysgenesis 1 | 19
Respiratory Distress Syndrome 1 | 15
Rudimentary vagina 1 | 14
Sclerocystic Ovaries 1 | 17
Sex reversal 1 | 10
Short distal phalanges 1 | 50
Short limb dwarfism recognizable at birth 1 | 9
Short metatarsal 1 | 21
Shortening of all phalanges of fingers 1 | 2
Simple syndactyly of toes, first web space 1 | 23
Skeletal muscle neoplasm 1 | 8
Skin dimple 1 | 2
Skull defect 1 | 10
Small abnormally formed scapulae 1 | 2
Small face 1 | 10
Small testicle 1 | 75
Sparse axillary hair 1 | 28
Sparse pubic hair 1 | 31
Streak ovary 1 | 15
Swyer Syndrome 1 | 8
Syndactyly of fingers 1 | 48
Testicular hypogonadism 1 | 21
Testicular regression syndrome 1 | 9
Tibial bowing 1 | 19
Tracheobronchomalacia 1 | 2
True Hermaphroditism (disorder) 1 | 4
Upper airway obstruction 1 | 6
Urogenital sinus anomaly 1 | 15
XX males 1 | 3

Tissue

Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Blood and immune system 3 | 16,909
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

GO Process

positive regulation of cell pr... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nascent polypeptide-associated complex subunit alpha NACA Tbio Non-IDG -1.15827 23.3 50
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Bone morphogenetic protein 10 BMP10 Tbio Non-IDG -1.43436 26.2 268
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266