Development Level

Tbio 107 | 10,625
Tchem 47 | 1,890
Tclin 20 | 602
Tdark 7 | 7,003

IMPC Phenotype

preweaning lethality, complete... 10 | 633
decreased lean body mass 5 | 195
preweaning lethality, incomple... 5 | 260
enlarged heart 4 | 111
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased T cell number 3 | 31
decreased bone mineral content 3 | 157
decreased circulating insulin ... 3 | 75
decreased rib number 3 | 59
improved glucose tolerance 3 | 56
increased blood urea nitrogen ... 3 | 44
increased circulating alkaline... 3 | 119
increased vertical activity 3 | 18
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased prepulse inhibition 2 | 52
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased body weight 2 | 42
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
increased total body fat amoun... 2 | 57
abnormal QRS complex 1 | 25
abnormal coat-hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal nail morphology 1 | 7
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal snout morphology 1 | 18
abnormal stomach morphology 1 | 4
abnormal vibrissa morphology 1 | 17
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased IgG1 level 1 | 4
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased circulating LDL chol... 1 | 37
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased startle reflex 1 | 48
enlarged spleen 1 | 26
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating LDL chol... 1 | 15
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
increased neutrophil cell numb... 1 | 15
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
oligodactyly 1 | 14
short tibia 1 | 82
straub tail 1 | 26
thrombocytosis 1 | 23
vertebral fusion 1 | 23

Disease

ovarian cancer 122 | 8,491
osteosarcoma 100 | 7,933
Cancer 97 | 2,346
psoriasis 93 | 6,685
glioblastoma 84 | 5,572
medulloblastoma, large-cell 80 | 6,234
lung cancer 73 | 4,473
Breast cancer 62 | 3,098
invasive ductal carcinoma 59 | 2,950
malignant mesothelioma 59 | 3,163
atypical teratoid / rhabdoid tumor 58 | 4,369
non-small cell lung cancer 53 | 2,798
lung carcinoma 52 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 50 | 3,289
lung adenocarcinoma 49 | 2,714
pilocytic astrocytoma 49 | 3,086
ulcerative colitis 49 | 2,087
pediatric high grade glioma 48 | 2,712
interstitial cystitis 47 | 2,299
cystic fibrosis 46 | 1,670
pancreatic cancer 46 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
primitive neuroectodermal tumor 45 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,988
oligodendroglioma 42 | 2,849
Carcinoma 40 | 2,147
breast carcinoma 39 | 1,614
ependymoma 38 | 2,514
tuberculosis 36 | 1,563
subependymal giant cell astrocytoma 34 | 2,287
group 4 medulloblastoma 33 | 1,875
group 3 medulloblastoma 32 | 2,254
diabetes mellitus 31 | 1,663
ductal carcinoma in situ 31 | 1,745
pituitary cancer 31 | 1,972
primary pancreatic ductal adenocarcinoma 30 | 1,271
astrocytic glioma 29 | 2,241
colon cancer 29 | 1,475
gastric carcinoma 26 | 832
astrocytoma 25 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
Mammary Neoplasms 24 | 410
Rheumatoid Arthritis 23 | 1,170
adult high grade glioma 23 | 2,148
esophageal adenocarcinoma 23 | 737
juvenile dermatomyositis 23 | 1,189
posterior fossa group A ependymoma 23 | 1,511
Pick disease 22 | 1,893
acute quadriplegic myopathy 22 | 1,157
adrenocortical carcinoma 22 | 1,427
cutaneous lupus erythematosus 21 | 1,056
dermatomyositis 20 | 966
Kidney disease 19 | 397
sonic hedgehog group medulloblastoma 19 | 1,482
Atherosclerosis 18 | 275
medulloblastoma 17 | 1,524
nasopharyngeal carcinoma 17 | 1,056
primary Sjogren syndrome 17 | 788
Alzheimer's disease 16 | 644
Heart disease 16 | 279
active Crohn's disease 16 | 918
mucosa-associated lymphoid tissue lymphoma 16 | 480
spina bifida 16 | 1,064
Asthma 15 | 349
Liver carcinoma 15 | 217
Obesity 15 | 616
Atopic dermatitis 14 | 944
Cerebrovascular disease 14 | 231
Multiple myeloma 14 | 1,327
Neoplasm Invasiveness 14 | 127
Vascular disease 14 | 281
atypical teratoid/rhabdoid tumor 14 | 1,095
posterior fossa group B ependymoma 14 | 1,530
Coronary artery disease 13 | 240
Duchenne muscular dystrophy 13 | 602
Multiple Sclerosis 13 | 498
Prostatic Neoplasms 13 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
pancreatic carcinoma 13 | 567
Arthritis 12 | 248
Liver Cirrhosis 12 | 101
Pulmonary Fibrosis 12 | 66
Renal Cell Carcinoma 12 | 199
non-small cell lung carcinoma 12 | 413
Endometriosis 11 | 535
Hypertension 11 | 293
Myocardial Ischemia 11 | 169
Neoplasm Metastasis 11 | 138
Stomach Neoplasms 11 | 282
active ulcerative colitis 11 | 477
fibroadenoma 11 | 557
hepatocellular carcinoma 11 | 550
urothelial carcinoma 11 | 318
Eosinophilia 10 | 65
Squamous cell carcinoma 10 | 96
Waldenstrons macroglobulinemia 10 | 764
progressive supranuclear palsy 10 | 674
Polycystic Ovary Syndrome 9 | 334
Schizophrenia 9 | 503
non primary Sjogren syndrome sicca 9 | 840

Tissue

Blood and immune system 180 | 17,994
Cardiovascular System 179 | 17,957
Digestive Tract 179 | 18,472
Endocrine System 179 | 18,511
Female tissues 179 | 18,646
Liver and Pancreas 179 | 18,135
Nervous System 179 | 18,560
Skin and soft tissues 179 | 18,114
Urinary Tract 179 | 18,443
Male tissues 178 | 17,968
Respiratory system 177 | 17,483

Target Family

Non-IDG 107 | 11,969
Kinase 31 | 634
Enzyme 20 | 4,146
Transcription Factor 13 | 1,400
GPCR 8 | 408
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

positive regulation of cell mi... 181 | 181
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.84299 53.1 358
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.94271 807.7 451
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.84344 79.9 342
Hepatocyte growth factor HGF Tchem Enzyme -3.29371 2317.3 573
Disabled homolog 2 DAB2 Tbio Non-IDG -2.24622 174.6 226
Proteinase-activated receptor 1 F2R Tclin GPCR -2.76897 534.6 399
Tumor necrosis factor-inducible gene 6 protein TNFAIP6 Tbio Non-IDG -2.15384 168.8 100
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.22534 1564.7 495
GTPase HRas HRAS Tchem Enzyme -3.99319 9497.9 312