Development Level

Tbio 32 | 11,445
Tchem 9 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased circulating insulin ... 2 | 76
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
abnormal body wall morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cataract 1 | 92
cleft palate 1 | 8
decreased body weight 1 | 161
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased spleen weight 1 | 10
edema 1 | 59
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
no spontaneous movement 1 | 1
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Cancer 39 | 2,499
malignant mesothelioma 26 | 3,232
lung cancer 25 | 4,740
Carcinoma 24 | 11,493
psoriasis 23 | 6,694
ovarian cancer 22 | 8,520
Breast cancer 19 | 3,578
osteosarcoma 19 | 7,950
cystic fibrosis 16 | 1,696
ependymoma 16 | 4,679
interstitial cystitis 16 | 2,312
invasive ductal carcinoma 16 | 2,951
lung carcinoma 16 | 2,843
group 3 medulloblastoma 15 | 4,104
glioblastoma 14 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung adenocarcinoma 14 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
medulloblastoma, large-cell 13 | 6,241
pancreatic cancer 13 | 2,398
Cleft Palate 12 | 271
diabetes mellitus 12 | 1,728
ductal carcinoma in situ 12 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
non-small cell lung cancer 11 | 2,890
ulcerative colitis 11 | 1,819
Astrocytoma, Pilocytic 10 | 3,081
Atherosclerosis 10 | 291
Pulmonary Fibrosis 10 | 106
Schizophrenia 10 | 1,160
adrenocortical carcinoma 10 | 1,428
atypical teratoid / rhabdoid tumor 10 | 5,112
tuberculosis 10 | 2,010
Breast Neoplasms 9 | 445
Cleft Lip 9 | 141
Coronary artery disease 9 | 268
Liver Cirrhosis, Experimental 9 | 769
Mammary Neoplasms 9 | 425
adult high grade glioma 9 | 3,801
breast carcinoma 9 | 1,638
pituitary cancer 9 | 1,972
Depressive disorder 8 | 409
Hypertensive disease 8 | 292
Kidney disease 8 | 430
colon cancer 8 | 1,478
Carcinoma, Hepatocellular 7 | 228
Down syndrome 7 | 499
Heart disease 7 | 306
Hypertension 7 | 396
Liver carcinoma 7 | 240
oligodendroglioma 7 | 2,850
spina bifida 7 | 1,074
Alzheimer's disease 6 | 658
Arthritis 6 | 290
Atopic dermatitis 6 | 952
Cardiomegaly 6 | 116
Inflammation 6 | 120
Lung disease 6 | 142
Parkinson's disease 6 | 392
Reperfusion Injury 6 | 86
Seizures 6 | 596
aldosterone-producing adenoma 6 | 665
astrocytic glioma 6 | 2,597
cutaneous lupus erythematosus 6 | 1,057
fibroadenoma 6 | 559
pancreatic carcinoma 6 | 562
Abortion, Spontaneous 5 | 109
Adenocarcinoma 5 | 122
Craniofacial Abnormalities 5 | 151
Diabetic retinopathy 5 | 56
Endometriosis 5 | 540
Hyperglycemia 5 | 137
Liver Cirrhosis 5 | 181
Lung Neoplasms 5 | 232
Mesothelioma 5 | 38
Myocardial Ischemia 5 | 169
Obesity 5 | 678
Proliferative vitreoretinopathy 5 | 17
Prostatic Neoplasms 5 | 495
Spontaneous abortion 5 | 113
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
dermatomyositis 5 | 966
gastric cancer 5 | 459
non-small cell lung carcinoma 5 | 317
Bipolar Disorder 4 | 666
Cerebrovascular disease 4 | 238
Hypersensitivity reaction type II disease 4 | 253
Inflammatory bowel disease 4 | 151
Mental Depression 4 | 333
Pick disease 4 | 1,894
Synostosis 4 | 15
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
nephrosclerosis 4 | 333
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 46 | 18,159
Digestive Tract 45 | 17,369
Nervous System 45 | 16,725
Skin and soft tissues 45 | 17,230
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Respiratory system 44 | 16,393
Urinary Tract 44 | 16,678
Blood and immune system 43 | 16,909
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 39 | 12,091
Transcription Factor 4 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634

GO Process

positive regulation of cell di... 47 | 47
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Platelet basic protein PPBP Tbio Non-IDG -3.18788 1559.1 453
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.07061 109.8 192
Zinc finger protein 16 ZNF16 Tbio Transcription Factor -0.64765 4.67 93
Integrin beta-1-binding protein 1 ITGB1BP1 Tbio Non-IDG -1.23128 20.8 138
Pleiotrophin PTN Tbio Non-IDG -2.85163 746.7 392
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384