Development Level

Tbio 30 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 27 | 11,493
Cancer 23 | 2,499
medulloblastoma, large-cell 18 | 6,241
ovarian cancer 17 | 8,520
psoriasis 17 | 6,694
lung cancer 16 | 4,740
osteosarcoma 16 | 7,950
ependymoma 14 | 4,679
glioblastoma 14 | 5,792
Breast cancer 11 | 3,578
diabetes mellitus 10 | 1,728
interstitial cystitis 10 | 2,312
pituitary cancer 10 | 1,972
atypical teratoid / rhabdoid tumor 9 | 5,112
cystic fibrosis 9 | 1,696
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
malignant mesothelioma 9 | 3,232
Hypertensive disease 8 | 292
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
Hypertension 6 | 396
Kidney cancer 6 | 2,613
Lung Neoplasms 6 | 232
Prostatic Neoplasms 6 | 495
Schizophrenia 6 | 1,160
astrocytic glioma 6 | 2,597
group 4 medulloblastoma 6 | 1,855
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Arthritis 5 | 290
Astrocytoma, Pilocytic 5 | 3,081
Bipolar Disorder 5 | 666
Heart disease 5 | 306
Hyperglycemia 5 | 137
Kidney disease 5 | 430
Obesity 5 | 678
Sensorineural Hearing Loss (disorder) 5 | 284
Weight decreased 5 | 103
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer's disease 4 | 658
Atherosclerosis 4 | 291
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
Carcinoma, Hepatocellular 4 | 228
Congenital hypoplasia of penis 4 | 176
Craniofacial Abnormalities 4 | 151
Hyperhidrosis disorder 4 | 81
Increased sweating 4 | 81
Liver Cirrhosis 4 | 181
Liver carcinoma 4 | 240
Liver disease 4 | 237
Nausea and vomiting 4 | 97
Neuropathy 4 | 261
Peripheral Neuropathy 4 | 134
Rheumatoid arthritis 4 | 1,191
Status Epilepticus 4 | 98
Sweating 4 | 81
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
gastric cancer 4 | 459
maturity-onset diabetes of the young 4 | 32
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
urothelial carcinoma 4 | 318
Adenoma 3 | 167
Autistic Disorder 3 | 364
Cerebrovascular disease 3 | 238
Coronary artery disease 3 | 268
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Epilepsy 3 | 792
Hernia, Inguinal 3 | 89
Leukemia 3 | 104
Liver Cirrhosis, Experimental 3 | 769
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Parkinson's disease 3 | 392
Polycystic ovary syndrome 3 | 360
Seizures 3 | 596
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
chronic lymphosyte leukemia 3 | 204
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
lung adenocarcinoma 3 | 2,716
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 37 | 18,159
Digestive Tract 36 | 17,369
Nervous System 35 | 16,725
Blood and immune system 34 | 16,909
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Skin and soft tissues 34 | 17,230
Urinary Tract 33 | 16,678
Respiratory system 31 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Transcription Factor 18 | 1,400
Non-IDG 13 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145
Nuclear Receptor 1 | 48

GO Process

positive regulation of cell di... 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Neurogenic differentiation factor 4 NEUROD4 Tbio Transcription Factor -1.14336 11.7 62
Homeobox protein CDX-2 CDX2 Tbio Transcription Factor -2.91273 837.0 699
Ribosomal protein S6 kinase alpha-3 RPS6KA3 Tchem Kinase -2.50143 325.4 425
POU domain, class 4, transcription factor 2 POU4F2 Tbio Transcription Factor -1.94397 90.2 145
RelA-associated inhibitor PPP1R13L Tbio Non-IDG -1.76131 64.5 185
Heat shock factor protein 4 HSF4 Tbio Transcription Factor -2.82845 672.2 263
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Endothelin-3 EDN3 Tbio Non-IDG -2.96371 794.0 219
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474