Development Level

Tbio 21 | 11,445
Tchem 7 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal motor capabilities-co... 1 | 5
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating magnesiu... 1 | 13
decreased heart rate 1 | 18
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
female infertility 1 | 60
increased circulating chloride... 1 | 41
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
male infertility 1 | 123
prolonged RR interval 1 | 8
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 21 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 13 | 6,241
Cancer 12 | 2,499
lung cancer 11 | 4,740
malignant mesothelioma 11 | 3,232
psoriasis 11 | 6,694
atypical teratoid / rhabdoid tumor 10 | 5,112
glioblastoma 10 | 5,792
Breast cancer 9 | 3,578
ependymoma 9 | 4,679
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
Astrocytoma, Pilocytic 8 | 3,081
adult high grade glioma 8 | 3,801
group 3 medulloblastoma 8 | 4,104
cystic fibrosis 7 | 1,696
diabetes mellitus 7 | 1,728
nasopharyngeal carcinoma 7 | 1,058
ulcerative colitis 7 | 1,819
Lung Neoplasms 6 | 232
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Breast Neoplasms 4 | 445
Depressive disorder 4 | 409
Liver cancer 4 | 604
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Small cell carcinoma of lung 4 | 45
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
primary pancreatic ductal adenocarcinoma 4 | 1,109
Actinic keratosis 3 | 21
Adenocarcinoma 3 | 122
Adenoma 3 | 167
Adrenal Gland Neoplasms 3 | 11
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Barrett's esophagus 3 | 182
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Squamous Cell 3 | 110
Cell Transformation, Neoplastic 3 | 97
Cervix uteri carcinoma in situ 3 | 16
Hypertensive disease 3 | 292
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Li-Fraumeni syndrome 3 | 13
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Myocardial Infarction 3 | 151
Neoplasm Invasiveness 3 | 161
Neoplasms 3 | 63
Neoplastic Cell Transformation 3 | 89
Neurodegenerative disease 3 | 414
Pancreatic carcinoma, familial 3 | 8
Papilloma 3 | 44
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
Small Cell Lung Carcinoma 3 | 41
Squamous cell carcinoma 3 | 129
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
posterior fossa group A ependymoma 3 | 468
tuberculosis 3 | 2,010
Abnormality of metabolism/homeostasis 2 | 134
Acquired metabolic disease 2 | 336
Adenoid Cystic Carcinoma 2 | 99
Bladder Neoplasm 2 | 112
Carcinoma, Adenoid Cystic 2 | 99
Exophthalmos 2 | 112
Inflammation 2 | 120
Mesothelioma, Malignant 2 | 105
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Osteoporosis 2 | 363
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Skeletal muscle atrophy 2 | 139
Skin cancer 2 | 469
Urinary Bladder Neoplasms 2 | 114
muscle degeneration 2 | 139

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Skin and soft tissues 28 | 17,230
Female tissues 27 | 17,400
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Liver and Pancreas 26 | 16,750
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 10 | 12,091
Transcription Factor 10 | 1,400
Enzyme 5 | 4,145
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

positive regulation of cell cy... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Rho family-interacting cell polarization regulator 2 RIPOR2 Tbio Non-IDG -0.97707 10.8 109
Prolyl endopeptidase FAP FAP Tchem Enzyme -2.37686 226.2 406
Mediator of RNA polymerase II transcription subunit 25 MED25 Tbio Enzyme -1.76765 57.1 86
POU domain, class 4, transcription factor 1 POU4F1 Tbio Transcription Factor -2.19846 154.8 107
RING finger protein 112 RNF112 Tbio Non-IDG -2.36685 229.7 118
Forkhead box protein O4 FOXO4 Tbio Transcription Factor -2.43923 278.0 720
60S ribosomal protein L23 RPL23 Tbio Non-IDG -1.57812 38.1 118
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235