Development Level

Tbio 19 | 11,651
Tchem 5 | 1,388
Tclin 2 | 612

IMPC Phenotype

abnormal embryo size 2 | 220
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal tail morphology 1 | 25
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased prepulse inhibition 1 | 32
pale yolk sac 1 | 25
pallor 1 | 34
respiratory system phenotype 1 | 2
unresponsive to tactile stimul... 1 | 8

Disease

medulloblastoma, large-cell 14 | 6,241
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
glioblastoma 12 | 5,792
Cancer 11 | 2,499
Carcinoma 11 | 11,493
atypical teratoid / rhabdoid tumor 11 | 5,112
Alzheimer's disease 10 | 658
lung cancer 9 | 4,740
psoriasis 9 | 6,694
diabetes mellitus 8 | 1,728
Schizophrenia 7 | 1,160
primitive neuroectodermal tumor 7 | 3,035
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
tuberculosis 6 | 2,010
Alzheimer Disease 5 | 83
Bipolar Disorder 5 | 666
Depressive disorder 5 | 409
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
pituitary cancer 5 | 1,972
Autosomal recessive predisposition 4 | 1,442
Disease Models, Animal 4 | 155
Heart failure 4 | 162
Multiple myeloma 4 | 1,332
Muscle Weakness 4 | 170
Nerve Degeneration 4 | 121
Neurodegenerative disease 4 | 414
Short stature 4 | 531
Waldenstrons macroglobulinemia 4 | 765
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
subependymal giant cell astrocytoma 4 | 2,287
urothelial carcinoma 4 | 318
Acquired scoliosis 3 | 281
Advanced bone age 3 | 35
Amyotrophic lateral sclerosis 3 | 451
Asphyxia neonatorum 3 | 11
Asthma 3 | 385
Atherosclerosis 3 | 291
Babinski Reflex 3 | 100
Breast Neoplasms 3 | 445
Cardiomegaly 3 | 116
Cardiomyopathy 3 | 116
Colonic Neoplasms 3 | 142
Colorectal Neoplasms 3 | 243
Congestive heart failure 3 | 113
Curvature of spine 3 | 282
Deglutition Disorders 3 | 132
Dementia 3 | 175
Diabetes Mellitus, Experimental 3 | 108
Down syndrome 3 | 499
Dysarthria 3 | 192
Fatigue 3 | 182
Fetal Growth Retardation 3 | 189
Frontotemporal dementia 3 | 51
Hidradenitis suppurativa 3 | 13
Hidradenitis suppurativa, familial 3 | 3
Hypertension 3 | 396
Hypertensive disease 3 | 292
Intellectual disability 3 | 1,016
Isolated cases 3 | 72
Mammary Neoplasms 3 | 425
Memory Disorders 3 | 40
Mental Depression 3 | 333
Parkinson's disease 3 | 392
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
Weight decreased 3 | 103
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
ulcerative colitis 3 | 1,819
Alcoholic Intoxication, Chronic 2 | 289
Autistic Disorder 2 | 364
Dilated cardiomyopathy 2 | 56
Dystonia 2 | 164
Dystonic disease 2 | 106
Frontal bossing 2 | 157
Gait Ataxia 2 | 51
Muscle Spasticity 2 | 195
Neuronal loss 2 | 25
Personality change 2 | 23
Retinal Degeneration 2 | 106
Toxic encephalopathy 2 | 141
posterior fossa group B ependymoma 2 | 416

Tissue

Nervous System 26 | 16,725
Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Male tissues 25 | 17,142
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Liver and Pancreas 24 | 16,750
Respiratory system 24 | 16,393

Target Family

Non-IDG 13 | 12,091
Enzyme 11 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

positive regulation of catalyt... 26 | 26
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.06798 109.1 482
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 Tbio Enzyme -1.43805 32.2 112
Gamma-secretase subunit APH-1B APH1B Tbio Enzyme -1.17035 13.6 56
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
Syntaxin-4 STX4 Tbio Non-IDG -1.95295 84.2 207
Insulin-like growth factor II IGF2 Tbio Non-IDG -3.65750 4465.3 457
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Nicastrin NCSTN Tbio Non-IDG -2.15220 133.2 357
Antizyme inhibitor 2 AZIN2 Tbio Enzyme -2.05244 97.6 50
Phosphatase and actin regulator 4 PHACTR4 Tbio Enzyme -0.75900 6.19 88