Development Level

Tbio 15 | 10,625
Tchem 9 | 1,890
Tclin 2 | 602

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal embryo size 1 | 112
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal tail morphology 1 | 17
cyanosis 1 | 6
decreased basophil cell number 1 | 11
decreased bone mineral content 1 | 157
edema 1 | 11
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
hemorrhage 1 | 12
hydrops fetalis 1 | 22
respiratory system phenotype 1 | 2

Disease

medulloblastoma, large-cell 14 | 6,234
osteosarcoma 13 | 7,933
glioblastoma 12 | 5,572
ovarian cancer 12 | 8,492
Alzheimer's disease 11 | 644
Cancer 11 | 2,346
psoriasis 10 | 6,685
atypical teratoid / rhabdoid tumor 9 | 4,369
lung cancer 9 | 4,473
diabetes mellitus 8 | 1,663
primitive neuroectodermal tumor 7 | 3,031
lung adenocarcinoma 6 | 2,714
pilocytic astrocytoma 6 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
juvenile dermatomyositis 5 | 1,189
malignant mesothelioma 5 | 3,163
non-small cell lung cancer 5 | 2,798
pediatric high grade glioma 5 | 2,712
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 1,563
Hidradenitis suppurativa 4 | 12
Multiple myeloma 4 | 1,328
Nerve Degeneration 4 | 73
Neurodegenerative disease 4 | 383
Waldenstrons macroglobulinemia 4 | 765
adult high grade glioma 4 | 2,148
colon cancer 4 | 1,475
ependymoma 4 | 2,514
group 4 medulloblastoma 4 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
invasive ductal carcinoma 4 | 2,950
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
urothelial carcinoma 4 | 318
Asphyxia neonatorum 3 | 9
Atherosclerosis 3 | 275
Breast cancer 3 | 3,099
Cardiomyopathy 3 | 110
Colonic Neoplasms 3 | 126
Colorectal Neoplasms 3 | 217
Diabetes Mellitus, Experimental 3 | 106
Down syndrome 3 | 548
Frontotemporal dementia 3 | 47
Hidradenitis suppurativa, familial 3 | 3
Hypertensive disease 3 | 193
Mammary Neoplasms 3 | 410
Memory Disorders 3 | 36
Parkinson's disease 3 | 364
Prostatic Neoplasms 3 | 471
acute myeloid leukemia 3 | 785
dermatomyositis 3 | 967
ductal carcinoma in situ 3 | 1,745
medulloblastoma 3 | 1,524
nasopharyngeal carcinoma 3 | 1,056
posterior fossa group A ependymoma 3 | 1,511
primary pancreatic ductal adenocarcinoma 3 | 1,271
ulcerative colitis 3 | 2,087
Adenoma 2 | 165
Amyotrophic Lateral Sclerosis 2 | 432
Anemia 2 | 252
Autistic Disorder 2 | 320
Bipolar Disorder 2 | 266
Contact Dermatitis 2 | 80
Dementia 2 | 129
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Dilated cardiomyopathy 2 | 51
Duchenne muscular dystrophy 2 | 602
Glaucoma 2 | 135
Growth Disorders 2 | 33
Heart failure 2 | 80
Leukemia, Myelocytic, Acute 2 | 113
Liver Neoplasms, Experimental 2 | 48
Motor neuron disease 2 | 39
Myocardial Infarction 2 | 126
Necrosis 2 | 51
Neoplastic Cell Transformation 2 | 81
Parkinson Disease 2 | 105
Pick disease 2 | 1,893
Polycystic Ovary Syndrome 2 | 335
Prostate cancer 2 | 172
Reperfusion Injury 2 | 84
Retinal Degeneration 2 | 49
Schizophrenia 2 | 503
Scoliosis 2 | 40
Seizures 2 | 95
Stomach Neoplasms 2 | 282
Toxic encephalopathy 2 | 131
adrenocortical carcinoma 2 | 1,427
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
breast carcinoma 2 | 1,614
cystic fibrosis 2 | 1,670
esophageal adenocarcinoma 2 | 737
ovarian neoplasm 2 | 97
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
sonic hedgehog group medulloblastoma 2 | 1,482

Tissue

Endocrine System 26 | 18,512
Urinary Tract 26 | 18,444
Blood and immune system 25 | 17,995
Cardiovascular System 25 | 17,958
Digestive Tract 25 | 18,473
Female tissues 25 | 18,647
Liver and Pancreas 25 | 18,136
Male tissues 25 | 17,969
Nervous System 25 | 18,561
Respiratory system 25 | 17,484
Skin and soft tissues 25 | 18,115

Target Family

Non-IDG 13 | 11,969
Enzyme 11 | 4,146
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

positive regulation of catalyt... 26 | 26
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.05927 116.0 218
Gamma-secretase subunit APH-1B APH1B Tchem Enzyme -1.15543 13.7 52
Syntaxin-4 STX4 Tbio Non-IDG -1.93051 79.1 192
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.03321 102.4 440
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 Tbio Enzyme -1.41779 31.1 90
Insulin-like growth factor II IGF2 Tchem Non-IDG -3.64697 4331.7 362
Phosphatase and actin regulator 4 PHACTR4 Tbio Enzyme -0.73886 6.19 78
Presenilin-2 PSEN2 Tchem Enzyme -2.55846 585.2 282
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84368 678.2 177
Antizyme inhibitor 2 AZIN2 Tbio Enzyme -2.02657 94.5 45