Development Level

Tbio 9 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal retinal inner nuclear... 1 | 8
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased heart rate 1 | 23
shortened RR interval 1 | 17

Disease

Carcinoma 12 | 11,493
lung cancer 11 | 4,740
Breast cancer 10 | 3,578
ovarian cancer 10 | 8,520
Cancer 8 | 2,499
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
Heart disease 7 | 306
diabetes mellitus 7 | 1,728
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
ependymoma 6 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
ulcerative colitis 6 | 1,819
Cerebrovascular disease 5 | 238
Coronary artery disease 5 | 268
Diabetes Mellitus, Experimental 5 | 108
Hypertension 5 | 396
Myocardial Ischemia 5 | 169
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
osteosarcoma 5 | 7,950
Atherosclerosis 4 | 291
Autosomal recessive predisposition 4 | 1,442
Cardiomegaly 4 | 116
Kidney Diseases 4 | 114
Liver Cirrhosis, Experimental 4 | 769
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Pulmonary Fibrosis 4 | 106
Reperfusion Injury 4 | 86
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Anemia 3 | 365
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Atrial Fibrillation 3 | 124
Bipolar Disorder 3 | 666
Cardiomyopathies 3 | 110
Diabetic retinopathy 3 | 56
Diaphragmatic Hernia 3 | 40
Heart failure 3 | 162
Hernia, Diaphragmatic 3 | 40
Hyperalgesia 3 | 83
Hypertensive disease 3 | 292
Impotence 3 | 42
Infarction, Middle Cerebral Artery 3 | 33
Inflammation 3 | 120
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Neurodegenerative disease 3 | 414
Pneumonia 3 | 174
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Adenoma 2 | 167
Amyotrophic lateral sclerosis 2 | 451
Cardiovascular Diseases 2 | 59
Cholestasis 2 | 155
Depressive disorder 2 | 409
Down syndrome 2 | 499
Focal glomerulosclerosis 2 | 37
Glomerulosclerosis, Focal Segmental 2 | 28
Hypercholesterolemia 2 | 44
Liver Cirrhosis 2 | 181
Lung disease 2 | 142
Mental Depression 2 | 333
Motor delay 2 | 147
Neuropathy 2 | 261
Peripheral vascular disease 2 | 87
Pick disease 2 | 1,894
Psychotic Disorders 2 | 151
Renal Insufficiency 2 | 90
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
dermatomyositis 2 | 966
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Blood and immune system 16 | 16,909
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

positive regulation of cardiac... 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A Tchem Enzyme -1.92564 78.9 151
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.35296 2270.4 122
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Myotrophin MTPN Tbio Non-IDG -1.83102 66.7 64
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289
Bone morphogenetic protein 10 BMP10 Tbio Non-IDG -1.43436 26.2 268
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Twinfilin-1 TWF1 Tbio Non-IDG -1.08655 12.4 211
Calcium/calmodulin-dependent protein kinase type II subunit delta CAMK2D Tchem Kinase -1.37613 16.9 229
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555