Development Level

Tchem 5 | 1,598
Tbio 4 | 11,445
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
Cancer 6 | 2,499
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
osteosarcoma 5 | 7,950
pancreatic cancer 5 | 2,398
psoriasis 5 | 6,694
ulcerative colitis 5 | 1,819
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
Breast cancer 3 | 3,578
Liver Cirrhosis, Experimental 3 | 769
Obesity 3 | 678
Pick disease 3 | 1,894
Vascular disease 3 | 319
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Carcinoma, Hepatocellular 2 | 228
Cardiomyopathies 2 | 110
Cardiovascular Abnormalities 2 | 31
Cardiovascular Diseases 2 | 59
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Depressive disorder 2 | 409
Diabetes Mellitus, Experimental 2 | 108
Hyperalgesia 2 | 83
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypertrophy 2 | 17
Kidney cancer 2 | 2,613
Lipid metabolism disorder 2 | 114
Liver carcinoma 2 | 240
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Mental Depression 2 | 333
Myocardial Ischemia 2 | 169
Myocardial Reperfusion Injury 2 | 37
Myopathy 2 | 185
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Reperfusion Injury 2 | 86
Seizures 2 | 596
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Abnormal lung lobation 1 | 10
Abnormality of the penis 1 | 7
Alkalosis 1 | 2
Anuria 1 | 9
Aortic Aneurysm, Abdominal 1 | 9
Aqueductal Stenosis 1 | 5
Birth length greater than 97th percentile 1 | 5
Cardiomyopathy, Alcoholic 1 | 1
Conjunctival hamartoma 1 | 7
Familial hypercholesterolemia - heterozygous 1 | 6
Familial hypercholesterolemia - homozygous 1 | 7
Fibrous skin tumor of tuberous sclerosis 1 | 18
Gastrointestinal hamartomatous polyps 1 | 10
Gastrointestinal polyps 1 | 5
Hamartoma Syndrome, Multiple 1 | 10
Hamartomatous polyp 1 | 10
Hashimoto Disease 1 | 4
Hyperkeratosis, generalized 1 | 14
Intestinal Polyposis 1 | 6
Lipomatosis 1 | 12
Macule 1 | 19
Mixed hyperlipidemia 1 | 5
Multiple lipomata 1 | 7
Multiple, subcutaneous nodules 1 | 53
Polyp of large intestine 1 | 8
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
Sudden death 1 | 16
Thrombosis 1 | 46
Vascular Remodeling 1 | 3

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Kinase 4 | 634
Enzyme 3 | 4,145
Non-IDG 3 | 12,091

GO Process

positive regulation of cardiac... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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