Development Level

Tbio 93 | 11,445
Tchem 18 | 1,598
Tclin 7 | 613
Tdark 5 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal embryo size 4 | 220
decreased vertical activity 4 | 208
decreased lean body mass 3 | 135
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased startle reflex 3 | 112
preweaning lethality, incomple... 3 | 499
thrombocytopenia 3 | 56
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal body wall morphology 2 | 9
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal eyelid morphology 2 | 7
abnormal femur morphology 2 | 14
abnormal iris morphology 2 | 13
abnormal kidney morphology 2 | 65
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
narrow eye opening 2 | 12
persistence of hyaloid vascula... 2 | 33
abnormal brain morphology 1 | 13
abnormal embryo development 1 | 7
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent teeth 1 | 3
cleft palate 1 | 8
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
female infertility 1 | 60
fused cornea and lens 1 | 5
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
mammalian phenotype 1 | 17
microphthalmia 1 | 26
prenatal lethality 1 | 28
small thymus 1 | 16

Disease

ovarian cancer 80 | 8,520
Carcinoma 76 | 11,493
osteosarcoma 52 | 7,950
psoriasis 50 | 6,694
lung cancer 49 | 4,740
Cancer 44 | 2,499
glioblastoma 42 | 5,792
medulloblastoma, large-cell 37 | 6,241
Breast cancer 34 | 3,578
atypical teratoid / rhabdoid tumor 31 | 5,112
Multiple myeloma 30 | 1,332
group 3 medulloblastoma 30 | 4,104
malignant mesothelioma 29 | 3,232
ependymoma 26 | 4,679
Astrocytoma, Pilocytic 24 | 3,081
invasive ductal carcinoma 24 | 2,951
non-small cell lung cancer 24 | 2,890
Kidney cancer 23 | 2,613
adult high grade glioma 23 | 3,801
lung adenocarcinoma 23 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
astrocytic glioma 20 | 2,597
lung carcinoma 20 | 2,843
oligodendroglioma 20 | 2,850
pancreatic cancer 19 | 2,398
subependymal giant cell astrocytoma 19 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
interstitial cystitis 17 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
primitive neuroectodermal tumor 17 | 3,035
HIV Infections 15 | 102
breast carcinoma 15 | 1,638
cystic fibrosis 15 | 1,696
dermatomyositis 15 | 966
tuberculosis 15 | 2,010
Osteoporosis 14 | 363
colon cancer 14 | 1,478
group 4 medulloblastoma 14 | 1,855
diabetes mellitus 13 | 1,728
Autosomal recessive predisposition 12 | 1,442
Pick disease 12 | 1,894
pituitary cancer 12 | 1,972
Hypoplastic mandible condyle 11 | 275
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
ulcerative colitis 11 | 1,819
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
Schizophrenia 10 | 1,160
Waldenstrons macroglobulinemia 10 | 765
cutaneous lupus erythematosus 10 | 1,057
juvenile dermatomyositis 10 | 1,187
primary pancreatic ductal adenocarcinoma 10 | 1,109
Liver Cirrhosis, Experimental 9 | 769
adrenocortical carcinoma 9 | 1,428
astrocytoma 9 | 1,146
ductal carcinoma in situ 9 | 1,745
nasopharyngeal carcinoma 9 | 1,058
Duchenne muscular dystrophy 8 | 601
Intellectual disability 8 | 1,016
esophageal adenocarcinoma 8 | 737
non primary Sjogren syndrome sicca 8 | 891
spina bifida 8 | 1,074
Cleft Palate 7 | 271
Colorectal Neoplasms 7 | 243
Obesity 7 | 678
Parkinson's disease 7 | 392
acute quadriplegic myopathy 7 | 1,158
progressive supranuclear palsy 7 | 676
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Cleft Lip 6 | 141
Crohn's disease 6 | 321
Dull intelligence 6 | 645
Frontal bossing 6 | 157
Hypodontia 6 | 81
Liver cancer 6 | 604
Low intelligence 6 | 645
Mantle cell lymphoma 6 | 23
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Renal Cell Carcinoma 6 | 214
Short stature 6 | 531
active ulcerative colitis 6 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric carcinoma 6 | 807
primary Sjogren syndrome 6 | 735
Bipolar Disorder 5 | 666
Cognitive delay 5 | 608
Down syndrome 5 | 499
Endometriosis 5 | 540
Gingival Hyperplasia 5 | 34
Gingival Hypertrophy 5 | 34
Mental and motor retardation 5 | 608
Prostatic Neoplasms 5 | 495
acute myeloid leukemia 5 | 783
hepatocellular carcinoma 5 | 547
limb girdle muscular dystrophy 2A 5 | 213

Tissue

Endocrine System 122 | 18,159
Digestive Tract 121 | 17,369
Female tissues 121 | 17,400
Blood and immune system 120 | 16,909
Male tissues 120 | 17,142
Nervous System 120 | 16,725
Respiratory system 120 | 16,393
Skin and soft tissues 119 | 17,230
Urinary Tract 119 | 16,678
Liver and Pancreas 118 | 16,750
Cardiovascular System 115 | 15,192

Target Family

Enzyme 52 | 4,145
Non-IDG 52 | 12,091
Kinase 8 | 634
GPCR 5 | 408
Transcription Factor 5 | 1,400
Ion Channel 1 | 344

GO Process

positive regulation of canonic... 123 | 123
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Notchless protein homolog 1 NLE1 Tbio Non-IDG -2.69934 437.6 162
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Transmembrane protein 198 TMEM198 Tdark Non-IDG 0.70 0.40 6
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.52453 32.7 40
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181