Development Level

Tbio 22 | 11,445
Tclin 15 | 613
Tchem 8 | 1,598

Collection

GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased lean body mass 4 | 135
increased total body fat amoun... 4 | 134
abnormal bone structure 3 | 187
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased vertical activity 3 | 208
preweaning lethality, complete... 3 | 979
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased neutrophil cell numb... 2 | 42
enlarged heart 2 | 210
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal sleep behavior 1 | 70
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgE level 1 | 6
decreased T cell number 1 | 15
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased IgG2b level 1 | 1
increased bone mineral content 1 | 108
increased circulating lipase l... 1 | 3
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

Carcinoma 21 | 11,493
Cancer 17 | 2,499
Hypertension 15 | 396
diabetes mellitus 15 | 1,728
ependymoma 15 | 4,679
osteosarcoma 15 | 7,950
medulloblastoma, large-cell 14 | 6,241
oligodendroglioma 14 | 2,850
ovarian cancer 14 | 8,520
psoriasis 14 | 6,694
Schizophrenia 13 | 1,160
astrocytic glioma 13 | 2,597
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
Astrocytoma, Pilocytic 12 | 3,081
Obesity 11 | 678
group 3 medulloblastoma 11 | 4,104
lung adenocarcinoma 11 | 2,716
lung cancer 11 | 4,740
primitive neuroectodermal tumor 11 | 3,035
adult high grade glioma 10 | 3,801
interstitial cystitis 10 | 2,312
lung carcinoma 10 | 2,843
Bipolar Disorder 9 | 666
Depressive disorder 9 | 409
Hypothyroidism 9 | 122
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung cancer 9 | 2,890
Adenoma 8 | 167
Mental Depression 8 | 333
invasive ductal carcinoma 8 | 2,951
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
Heart disease 7 | 306
Kidney cancer 7 | 2,613
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
ulcerative colitis 7 | 1,819
Alzheimer's disease 6 | 658
Cerebrovascular disease 6 | 238
Cushing's syndrome 6 | 48
Diarrhea 6 | 253
Epilepsy 6 | 792
Hypertensive disease 6 | 292
Hypoglycemia 6 | 152
Kidney disease 6 | 430
Pick disease 6 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Coronary artery disease 5 | 268
Hypercalcemia 5 | 59
Hyperthyroidism 5 | 53
Hypopituitarism 5 | 40
Hypotension 5 | 82
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
fibroadenoma 5 | 559
malignant mesothelioma 5 | 3,232
Acromegaly 4 | 51
Alcohol dependence 4 | 107
Autistic Disorder 4 | 364
Erythropoietic protoporphyria 4 | 15
Heart failure 4 | 162
Hyperalgesia 4 | 83
Hyperparathyroidism 4 | 48
Hypoparathyroidism 4 | 41
Multiple Endocrine Neoplasia Type 1 4 | 29
Osteoporosis 4 | 363
Pain 4 | 103
Pancreatitis 4 | 123
Pituitary adenoma 4 | 38
Pseudohypoparathyroidism 4 | 18
Seizures 4 | 596
Short stature 4 | 531
Ventricular arrhythmia 4 | 27
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
Alcoholic Intoxication, Chronic 3 | 289
Arthritis 3 | 290
Atherosclerosis 3 | 291
Fever 3 | 138
Major Depressive Disorder 3 | 301
Mood Disorders 3 | 184
Tachycardia 3 | 43
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
Vascular disease 3 | 319
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 44 | 18,159
Digestive Tract 39 | 17,369
Skin and soft tissues 38 | 17,230
Female tissues 37 | 17,400
Blood and immune system 36 | 16,909
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Respiratory system 35 | 16,393
Urinary Tract 35 | 16,678
Nervous System 34 | 16,725
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 21 | 12,091
GPCR 18 | 408
Enzyme 3 | 4,145
Kinase 2 | 634
Transporter 1 | 473

GO Process

positive regulation of cAMP bi... 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Melanocortin receptor 3 MC3R Tchem GPCR -2.65556 445.3 202
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Glycoprotein hormone beta-5 GPHB5 Tbio Non-IDG 0.00000 54
A-kinase anchor protein 12 AKAP12 Tbio Enzyme -2.00948 126.8 160
ADM ADM Tbio Non-IDG -3.27504 1889.0 381
Psychosine receptor GPR65 Tbio GPCR -1.53268 38.5 173