Development Level

Tbio 6 | 11,651
Tchem 4 | 1,388
Tclin 3 | 612
Tdark 2 | 6,593

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal optic disc morphology 1 | 10
abnormal vertebrae morphology 1 | 18
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased total body fat amoun... 1 | 134
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

ovarian cancer 10 | 8,519
Carcinoma 9 | 11,493
medulloblastoma, large-cell 9 | 6,241
lung cancer 8 | 4,740
osteosarcoma 8 | 7,950
Cancer 7 | 2,499
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,290
invasive ductal carcinoma 6 | 2,950
Breast cancer 5 | 3,577
ductal carcinoma in situ 5 | 1,744
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
ulcerative colitis 5 | 1,819
Arthritis 4 | 290
Astrocytoma, Pilocytic 4 | 3,081
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
Obesity 4 | 678
Osteopetrosis 4 | 43
Osteoporosis 4 | 363
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,695
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,954
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
lung adenocarcinoma 4 | 2,716
psoriasis 4 | 6,694
Adenocarcinoma 3 | 122
Anemia 3 | 365
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Lung Neoplasms 3 | 232
Mesothelioma 3 | 38
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
malignant mesothelioma 3 | 3,232
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 336
Acute kidney injury 2 | 70
Alcoholic Intoxication, Chronic 2 | 289
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Chemical and Drug Induced Liver Injury 2 | 195
Class III malocclusion 2 | 78
Colorectal Neoplasms 2 | 243
Decreased platelet count 2 | 111
Down syndrome 2 | 499
Esophageal Squamous Cell Carcinoma 2 | 77
Failure to gain weight 2 | 365
Frequent fractures 2 | 53
Hemoglobin low 2 | 124
Hepatomegaly 2 | 285
Hypersensitivity reaction type II disease 2 | 253
Increased fracture rate 2 | 53
Increased size of mandible 2 | 78
Kidney disease 2 | 430
Leukemia, Lymphocytic, Chronic, B-Cell 2 | 34
Liver carcinoma 2 | 240
Lung disease 2 | 142
Malaria 2 | 160
Mammary Neoplasms, Experimental 2 | 154
Mandibular hyperplasia 2 | 78
Melanoma 2 | 711
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Neoplasm Metastasis 2 | 168
Pancytopenia 2 | 45
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Squamous cell carcinoma of esophagus 2 | 77
Stomach Neoplasms 2 | 300
Thrombocytopenia 2 | 197
Urinary Bladder Neoplasms 2 | 114
Varying degree of multiple fractures 2 | 53
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,637
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
limb girdle muscular dystrophy 2A 2 | 213
mandibular excess (physical finding) 2 | 78
non diabetic and post-ischemic heart failure 2 | 200
pediatric high grade glioma 2 | 1,064
sarcoidosis 2 | 370

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Male tissues 14 | 17,142
Urinary Tract 14 | 16,678
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 12 | 17,230
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 9 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
GPCR 1 | 408

GO Process

positive regulation of bone re... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.14835 1437.4 1136
Differentially expressed in FDCP 8 homolog DEF8 Tdark Non-IDG -0.47697 3.11 97
Peroxisome proliferator-activated receptor gamma coactivator 1-beta PPARGC1B Tbio Non-IDG -2.68495 463.1 52
Transmembrane protein 64 TMEM64 Tdark Non-IDG -0.22185 1.46 9
Follitropin subunit beta FSHB Tbio Non-IDG -2.18224 143.3 599
Osteopontin SPP1 Tbio Non-IDG -3.66384 4916.5 1053
Tumor necrosis factor ligand superfamily member 11 TNFSF11 Tclin Non-IDG -3.58408 4276.7 781
Melanocortin receptor 4 MC4R Tchem GPCR -2.95116 930.2 251
Dendritic cell-specific transmembrane protein DCSTAMP Tbio Non-IDG -2.01301 97.3 42
Pleckstrin homology domain-containing family M member 1 PLEKHM1 Tbio Non-IDG -1.44998 27.9 116