Development Level

Tbio 21 | 11,445
Tchem 9 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 3 | 220
abnormal behavior 2 | 298
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal stomach morphology 1 | 10
abnormal tail morphology 1 | 25
decreased bone mineral content 1 | 151
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased monocyte cell number 1 | 63
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 28 | 11,493
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 17 | 6,241
osteosarcoma 17 | 7,950
glioblastoma 16 | 5,792
adult high grade glioma 15 | 3,801
psoriasis 15 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
ependymoma 13 | 4,679
Kidney cancer 12 | 2,613
oligodendroglioma 12 | 2,850
Cancer 11 | 2,499
Astrocytoma, Pilocytic 9 | 3,081
Intellectual disability 9 | 1,016
astrocytic glioma 9 | 2,597
group 4 medulloblastoma 9 | 1,855
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
Alzheimer's disease 8 | 658
Breast cancer 8 | 3,578
lung carcinoma 8 | 2,843
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
Schizophrenia 7 | 1,160
acute quadriplegic myopathy 7 | 1,158
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
cystic fibrosis 6 | 1,696
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Autistic Disorder 5 | 364
Pick disease 5 | 1,894
dermatomyositis 5 | 966
hereditary spastic paraplegia 5 | 318
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
primitive neuroectodermal tumor 5 | 3,035
Depressive disorder 4 | 409
Epilepsy 4 | 792
Heart disease 4 | 306
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Waldenstrons macroglobulinemia 4 | 765
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
sonic hedgehog group medulloblastoma 4 | 467
Bilateral fifth finger clinodactyly 3 | 110
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Curvature of little finger 3 | 110
Dilated ventricles (finding) 3 | 121
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Gastroesophageal reflux disease 3 | 110
Global developmental delay 3 | 608
Kidney disease 3 | 430
Lissencephaly 3 | 69
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle Spasticity 3 | 195
Proteinuria 3 | 144
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Short nose 3 | 132
Short stature 3 | 531
Small head 3 | 374
Small nose 3 | 132
Stereotyped Behavior 3 | 37
Stereotypic Movement Disorder 3 | 42
Strabismus 3 | 270
Vascular disease 3 | 319
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
limb girdle muscular dystrophy 2A 3 | 213
nephrosclerosis 3 | 333
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Anteverted nostril 2 | 191
Broad flat nasal bridge 2 | 236
Chronic obstructive pulmonary disease 2 | 184
Congenital Epicanthus 2 | 177
Hypertension 2 | 396
Long philtrum 2 | 137
Nasal bridge wide 2 | 236
type II diabetes mellitus and post-ischemic heart failure 2 | 88

Tissue

Endocrine System 31 | 18,159
Liver and Pancreas 31 | 16,750
Nervous System 31 | 16,725
Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Female tissues 30 | 17,400
Male tissues 30 | 17,142
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 20 | 12,091
Kinase 4 | 634
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Ion Channel 2 | 344

GO Process

positive regulation of axon ex... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
POU domain, class 4, transcription factor 2 POU4F2 Tbio Transcription Factor -1.94397 90.2 145
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Tumor necrosis factor receptor superfamily member 12A TNFRSF12A Tbio Non-IDG -2.13589 160.9 382
Cadherin-4 CDH4 Tbio Non-IDG -1.95165 92.7 193
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Activity-dependent neuroprotector homeobox protein ADNP Tbio Transcription Factor -2.00844 110.4 263
Protein RUFY3 RUFY3 Tdark Non-IDG -0.34045 2.69 43