Development Level

Tbio 30 | 11,651
Tchem 11 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating choleste... 2 | 93
embryonic lethality prior to t... 2 | 278
enlarged spleen 2 | 41
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
scaly skin 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 29 | 11,493
ovarian cancer 23 | 8,520
osteosarcoma 21 | 7,950
glioblastoma 19 | 5,792
medulloblastoma, large-cell 18 | 6,241
psoriasis 18 | 6,694
ependymoma 17 | 4,679
lung cancer 16 | 4,740
Cancer 15 | 2,499
Breast cancer 14 | 3,578
Astrocytoma, Pilocytic 13 | 3,081
atypical teratoid / rhabdoid tumor 13 | 5,112
oligodendroglioma 11 | 2,850
adult high grade glioma 10 | 3,801
ulcerative colitis 10 | 1,819
group 3 medulloblastoma 9 | 4,104
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
tuberculosis 8 | 2,010
Kidney cancer 7 | 2,613
astrocytic glioma 7 | 2,597
ductal carcinoma in situ 7 | 1,745
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
pediatric high grade glioma 7 | 1,064
Kidney disease 6 | 430
Schizophrenia 6 | 1,160
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
lung adenocarcinoma 6 | 2,716
pituitary cancer 6 | 1,972
Pick disease 5 | 1,894
Renal Cell Carcinoma 5 | 214
adrenocortical carcinoma 5 | 1,428
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
juvenile dermatomyositis 5 | 1,187
primary pancreatic ductal adenocarcinoma 5 | 1,109
Down syndrome 4 | 499
Inflammatory bowel disease 4 | 151
Neurodegenerative disease 4 | 414
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma 3 | 122
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Carcinoma, Renal Cell 3 | 124
Crohn's disease 3 | 321
Duchenne muscular dystrophy 3 | 601
Glucose Intolerance 3 | 19
Heart disease 3 | 306
Impaired glucose tolerance 3 | 28
Insulin Resistance 3 | 72
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Lung Neoplasms 3 | 232
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Nerve Degeneration 3 | 121
Obesity 3 | 678
Rheumatoid arthritis 3 | 1,191
Vascular disease 3 | 319
Vasculitis 3 | 80
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Anemia 2 | 365
Arthritis 2 | 290
Arthritis, Juvenile 2 | 126
Atherosclerosis 2 | 291
Bipolar Disorder 2 | 666
Endometriosis 2 | 540
Epilepsy 2 | 792
Glaucoma 2 | 239
Juvenile arthritis 2 | 126
Peritonitis 2 | 43
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
colon cancer 2 | 1,478
hepatocellular carcinoma 2 | 547
nasopharyngeal carcinoma 2 | 1,058
tuberculosis and treatment for 3 months 2 | 179

Tissue

Blood and immune system 42 | 16,909
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 9 | 4,145
Kinase 9 | 634
Transcription Factor 3 | 1,400
Ion Channel 1 | 344

GO Process

positive regulation of autopha... 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5'-AMP-activated protein kinase catalytic subunit alpha-2 PRKAA2 Tchem Kinase -1.42705 21.1 603
Serine/threonine-protein kinase PLK2 PLK2 Tchem Kinase -2.45914 273.4 179
Beclin 1-associated autophagy-related key regulator ATG14 Tbio Non-IDG -1.63390 38.6 127
GATOR complex protein NPRL2 NPRL2 Tbio Enzyme -1.30624 22.7 214
Protein LYRIC MTDH Tbio Non-IDG -2.60328 417.3 249
Death-associated protein kinase 1 DAPK1 Tchem Kinase -2.34153 226.1 276
Interferon gamma IFNG Tbio Non-IDG -3.90985 5727.4 2248
Immunity-related GTPase family M protein IRGM Tbio Enzyme -1.99868 103.7 169
TIR domain-containing adapter molecule 1 TICAM1 Tbio Non-IDG -1.50467 33.0 226
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 Tbio Non-IDG -2.51675 340.9 331