Development Level

Tbio 8 | 11,445
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 2 | 298
increased startle reflex 2 | 112
decreased heart rate 1 | 18
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8

Disease

Carcinoma 8 | 11,493
osteosarcoma 8 | 7,950
ovarian cancer 6 | 8,520
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
medulloblastoma, large-cell 4 | 6,241
Cancer 3 | 2,499
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Abnormal dermatoglyphic pattern 2 | 24
Abnormal visual evoked potential 2 | 26
Abnormality of nail of toe 2 | 11
Abnormality of retinal pigmentation 2 | 111
Abnormally small eyeball 2 | 97
Acquired scoliosis 2 | 281
Agyria 2 | 15
Anteverted nostril 2 | 191
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Blindness, Cortical 2 | 24
Brachycephaly 2 | 88
Breast cancer 2 | 3,578
Broad cranium shape 2 | 88
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cerebral atrophy 2 | 178
Clitoral hypoplasia 2 | 11
Concave bridge of nose 2 | 195
Congenital Bilateral Cataracts 2 | 50
Congenital cataract 2 | 50
Cortical visual impairment 2 | 24
Curvature of spine 2 | 282
Decreased projection of midface 2 | 105
Decreased size of eyeball 2 | 97
Delayed Puberty 2 | 97
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dull intelligence 2 | 645
Everted lower lip vermilion 2 | 54
Feeding difficulties in infancy 2 | 175
Fissured tongue 2 | 25
Generalized hirsutism 2 | 36
Hyperkyphosis 2 | 111
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypoplasia of corpus callosum 2 | 90
Hypoplasia or absence of the corpus callosum 2 | 23
Hypoplastic labia minora 2 | 10
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Joint stiffness 2 | 84
Kidney cancer 2 | 2,613
Kyphosis deformity of spine 2 | 114
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Lissencephaly 2 | 69
Lordosis 2 | 54
Low posterior hairline 2 | 52
Macrotia 2 | 87
Malar flattening 2 | 129
Mental and motor retardation 2 | 608
Microcephaly 2 | 166
Microphthalmia 2 | 76
Midface retrusion 2 | 105
Muscle Spasticity 2 | 195
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Pachygyria 2 | 41
Precociously senile appearance 2 | 18
Protruding lower lip 2 | 54
Retinal pigment epithelial abnormality 2 | 111
Rheumatoid arthritis 2 | 1,191
Severe mental retardation (I.Q. 20-34) 2 | 99
Short nose 2 | 132
Short philtrum 2 | 53
Small midface 2 | 105
Small nose 2 | 132
Ulnar deviation of the fingers 2 | 21
Warburg micro syndrome 2 | 18
Wide skull shape 2 | 88
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
posterior fossa group B ependymoma 2 | 416
steroid-induced glaucoma 2 | 8

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 4 | 4,145
Kinase 4 | 634
Non-IDG 3 | 12,091

GO Process

positive regulation of autopha... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endophilin-B1 SH3GLB1 Tbio Non-IDG -1.10096 14.5 386
Ras-related protein Ral-B RALB Tbio Enzyme -1.71078 50.9 228
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha PIP4K2A Tbio Kinase -1.77895 57.4 244
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137
E3 ubiquitin-protein ligase LRSAM1 LRSAM1 Tbio Enzyme -2.91737 790.7 119
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta PIP4K2B Tchem Kinase -0.91386 7.47 128
Rab3 GTPase-activating protein non-catalytic subunit RAB3GAP2 Tbio Enzyme -0.61182 2.71 65
Serine/threonine-protein kinase ULK1 ULK1 Tchem Kinase -2.57033 346.8 647
Rab3 GTPase-activating protein catalytic subunit RAB3GAP1 Tbio Enzyme -1.40654 26.0 104
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma PIP4K2C Tchem Kinase -0.39693 2.41 89