Development Level

Tbio 59 | 11,445
Tchem 49 | 1,598
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased vertical activity 4 | 208
preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal ovary morphology 2 | 7
decreased body weight 2 | 161
decreased circulating triglyce... 2 | 79
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hypoactivity 2 | 132
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
absent epididymis 1 | 3
absent optic nerve 1 | 2
decreased B cell number 1 | 5
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged heart atrium 1 | 4
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart rate 1 | 23
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased startle reflex 1 | 112
kinked tail 1 | 2
limb grasping 1 | 41
mammalian phenotype 1 | 17
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 74 | 11,493
ovarian cancer 72 | 8,520
Cancer 71 | 2,499
psoriasis 67 | 6,694
osteosarcoma 63 | 7,950
glioblastoma 62 | 5,792
lung cancer 62 | 4,740
invasive ductal carcinoma 46 | 2,951
lung adenocarcinoma 46 | 2,716
medulloblastoma, large-cell 45 | 6,241
malignant mesothelioma 44 | 3,232
non-small cell lung cancer 44 | 2,890
lung carcinoma 42 | 2,843
Breast cancer 41 | 3,578
cystic fibrosis 39 | 1,696
ependymoma 39 | 4,679
ulcerative colitis 37 | 1,819
Astrocytoma, Pilocytic 36 | 3,081
diabetes mellitus 36 | 1,728
interstitial cystitis 36 | 2,312
pancreatic cancer 35 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 34 | 2,955
group 3 medulloblastoma 33 | 4,104
tuberculosis 33 | 2,010
atypical teratoid / rhabdoid tumor 32 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
adult high grade glioma 29 | 3,801
breast carcinoma 29 | 1,638
Kidney disease 27 | 430
ductal carcinoma in situ 27 | 1,745
Hypertension 26 | 396
subependymal giant cell astrocytoma 25 | 2,287
pituitary cancer 22 | 1,972
primitive neuroectodermal tumor 22 | 3,035
Heart disease 21 | 306
adrenocortical carcinoma 21 | 1,428
oligodendroglioma 21 | 2,850
Atherosclerosis 20 | 291
Breast Neoplasms 20 | 445
Coronary artery disease 20 | 268
Mammary Neoplasms 20 | 425
Schizophrenia 20 | 1,160
Vascular disease 20 | 319
primary pancreatic ductal adenocarcinoma 20 | 1,109
Liver Cirrhosis, Experimental 19 | 769
Prostatic Neoplasms 19 | 495
Rheumatoid arthritis 19 | 1,191
Asthma 18 | 385
gastric carcinoma 18 | 807
acute quadriplegic myopathy 17 | 1,158
pediatric high grade glioma 17 | 1,064
Alzheimer's disease 16 | 658
Autosomal recessive predisposition 16 | 1,442
Kidney cancer 16 | 2,613
astrocytoma 16 | 1,146
colon cancer 16 | 1,478
cutaneous lupus erythematosus 16 | 1,057
dermatomyositis 16 | 966
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Anemia 15 | 365
Bipolar Disorder 15 | 666
Down syndrome 15 | 499
Obesity 15 | 678
Reperfusion Injury 15 | 86
mucosa-associated lymphoid tissue lymphoma 15 | 484
Atopic dermatitis 14 | 952
Pneumonia 14 | 174
active ulcerative colitis 14 | 764
astrocytic glioma 14 | 2,597
Cerebrovascular disease 13 | 238
Hypertensive disease 13 | 292
Lung disease 13 | 142
Multiple Sclerosis 13 | 540
Pulmonary Fibrosis 13 | 106
esophageal adenocarcinoma 13 | 737
group 4 medulloblastoma 13 | 1,855
Arthritis 12 | 290
Diabetic retinopathy 12 | 56
Hypersensitivity reaction type II disease 12 | 253
Myocardial Ischemia 12 | 169
Pick disease 12 | 1,894
juvenile dermatomyositis 12 | 1,187
nasopharyngeal carcinoma 12 | 1,058
Cardiomegaly 11 | 116
Dermatitis 11 | 157
Heart failure 11 | 162
Liver Cirrhosis 11 | 181
Multiple myeloma 11 | 1,332
fibroadenoma 11 | 559
hepatocellular carcinoma 11 | 547
Duchenne muscular dystrophy 10 | 601
Inflammatory bowel disease 10 | 151
Lung Neoplasms 10 | 232
Melanoma 10 | 711
Neoplasm Metastasis 10 | 168
Stomach Neoplasms 10 | 300
active Crohn's disease 10 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
gastric cancer 10 | 459

Tissue

Endocrine System 120 | 18,159
Digestive Tract 119 | 17,369
Blood and immune system 118 | 16,909
Liver and Pancreas 118 | 16,750
Female tissues 117 | 17,400
Urinary Tract 117 | 16,678
Male tissues 116 | 17,142
Respiratory system 116 | 16,393
Skin and soft tissues 116 | 17,230
Nervous System 114 | 16,725
Cardiovascular System 106 | 15,192

Target Family

Non-IDG 62 | 12,091
Enzyme 18 | 4,145
Kinase 15 | 634
Transcription Factor 13 | 1,400
GPCR 9 | 408
Ion Channel 2 | 344
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

positive regulation of angioge... 121 | 121
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Urotensin-2 receptor UTS2R Tchem GPCR -1.95094 62.5 182
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
Zinc finger protein 304 ZNF304 Tbio Transcription Factor -0.83471 4.32 16
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268