Development Level

Tbio 8 | 10,625
Tdark 2 | 7,003
Tchem 1 | 1,890

IMPC Phenotype

preweaning lethality, complete... 2 | 633
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating fructosa... 1 | 31
decreased circulating iron lev... 1 | 25
decreased total body fat amoun... 1 | 186
fused cornea and lens 1 | 4
increased circulating amylase ... 1 | 13

Disease

glioblastoma 7 | 5,572
medulloblastoma, large-cell 7 | 6,234
ovarian cancer 7 | 8,491
psoriasis 7 | 6,685
invasive ductal carcinoma 6 | 2,950
lung carcinoma 6 | 2,844
osteosarcoma 6 | 7,933
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
lung adenocarcinoma 5 | 2,714
lung cancer 5 | 4,473
non-small cell lung cancer 5 | 2,798
pilocytic astrocytoma 5 | 3,086
ulcerative colitis 5 | 2,087
Breast cancer 4 | 3,098
Cancer 4 | 2,346
astrocytoma 4 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
pancreatic cancer 4 | 2,300
Rheumatoid Arthritis 3 | 1,170
acute quadriplegic myopathy 3 | 1,157
atypical teratoid / rhabdoid tumor 3 | 4,369
breast carcinoma 3 | 1,614
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,299
malignant mesothelioma 3 | 3,163
pediatric high grade glioma 3 | 2,712
posterior fossa group B ependymoma 3 | 1,530
primary Sjogren syndrome 3 | 788
primitive neuroectodermal tumor 3 | 3,031
Amyotrophic Lateral Sclerosis 2 | 432
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Pick disease 2 | 1,893
Waldenstrons macroglobulinemia 2 | 764
adrenocortical carcinoma 2 | 1,427
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
medulloblastoma 2 | 1,524
oligodendroglioma 2 | 2,849
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Aortic valve stenosis 1 | 8
Atopic dermatitis 1 | 944
Atrial Fibrillation 1 | 110
Becker muscular dystrophy 1 | 187
COPD 1 | 116
Carcinoma 1 | 2,147
Celiac disease 1 | 112
Cowpox 1 | 15
Dacryoadenitis 1 | 7
Diabetes Mellitus, Experimental 1 | 106
Diabetes Mellitus, Non-Insulin-Dependent 1 | 161
Epithelial ovarian cancer 1 | 19
Galloway-Mowat syndrome 1 | 9
Heart conduction disease 1 | 65
IGA Glomerulonephritis 1 | 454
Intracranial aneurysm 1 | 20
Keloid 1 | 34
Kidney disease 1 | 397
Mammary Neoplasms, Experimental 1 | 149
Multiple Sclerosis 1 | 498
Multiple myeloma 1 | 1,327
Myocardial Ischemia 1 | 169
Nephroblastoma 1 | 45
Nephrolithiasis 1 | 31
Neurodegenerative disease 1 | 383
Osteoporosis 1 | 259
Squamous cell carcinoma of esophagus 1 | 82
Williams Syndrome 1 | 10
Williams-Beuren syndrome 1 | 45
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
adrenocortical adenoma 1 | 134
adult high grade glioma 1 | 2,148
astrocytic glioma 1 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
chronic rhinosinusitis 1 | 512
cutaneous lupus erythematosus 1 | 1,056
cystic fibrosis 1 | 1,670
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,663
ependymoma 1 | 2,514
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 832
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
hepatocellular carcinoma 1 | 550
hereditary spastic paraplegia 1 | 313
juvenile dermatomyositis 1 | 1,189
nasopharyngeal carcinoma 1 | 1,056
non-inflammatory breast cancer 1 | 208
pancreatic carcinoma 1 | 567
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
posterior fossa group A ependymoma 1 | 1,511
progressive supranuclear palsy 1 | 674
sarcoidosis 1 | 368
tuberculosis 1 | 1,563

Tissue

Blood and immune system 11 | 17,994
Cardiovascular System 11 | 17,957
Digestive Tract 11 | 18,472
Endocrine System 11 | 18,511
Female tissues 11 | 18,646
Liver and Pancreas 11 | 18,135
Male tissues 11 | 17,968
Nervous System 11 | 18,560
Respiratory system 11 | 17,483
Skin and soft tissues 11 | 18,114
Urinary Tract 11 | 18,443

Target Family

Non-IDG 9 | 11,969
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of actin f... 11 | 11
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptopodin-2 SYNPO2 Tbio Non-IDG -1.30742 25.6 32
Villin-1 VIL1 Tbio Non-IDG -2.18134 153.7 231
Profilin-3 PFN3 Tdark Non-IDG -0.89066 8.44 8
Profilin-2 PFN2 Tbio Non-IDG -1.92139 89.6 196
Pleckstrin PLEK Tbio Non-IDG -2.99140 713.7 264
Synaptopodin 2-like protein SYNPO2L Tdark Non-IDG -0.18223 1.23 43
Profilin-1 PFN1 Tbio Non-IDG -2.27552 199.6 237
Synaptopodin SYNPO Tbio Non-IDG -2.14672 124.0 176
LIM domain kinase 1 LIMK1 Tchem Kinase -2.25846 175.4 612
DNA-binding protein inhibitor ID-1 ID1 Tbio Transcription Factor -2.59932 414.3 295