Development Level

Tbio 8 | 11,651
Tdark 2 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal joint morphology 1 | 23
brachydactyly 1 | 19
corneal opacity 1 | 32
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
fused cornea and lens 1 | 5
increased circulating amylase ... 1 | 25
syndactyly 1 | 23

Disease

Carcinoma 7 | 11,493
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
invasive ductal carcinoma 6 | 2,951
lung carcinoma 6 | 2,843
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819
Breast cancer 4 | 3,578
Cancer 4 | 2,499
astrocytoma 4 | 1,146
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pancreatic cancer 4 | 2,398
Amyotrophic lateral sclerosis 3 | 451
Rheumatoid arthritis 3 | 1,191
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
interstitial cystitis 3 | 2,312
malignant mesothelioma 3 | 3,232
primary Sjogren syndrome 3 | 735
primitive neuroectodermal tumor 3 | 3,035
Anxiety 2 | 136
Anxiety disease 2 | 113
Depressive disorder 2 | 409
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Muscle Spasticity 2 | 195
Pick disease 2 | 1,894
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of the fingernails 1 | 51
Agammaglobulinemia 1 | 34
Bunion 1 | 26
Celiac disease 1 | 116
Cellulitis of periorbital region 1 | 13
Cerebellar Dysmetria 1 | 56
Colon diverticulum anatomic structure 1 | 15
Congenital anomaly of neck 1 | 19
Cowpox 1 | 16
Dacryoadenitis 1 | 10
Deformity of neck 1 | 19
Deglutition Disorders 1 | 132
Diabetes Mellitus, Experimental 1 | 108
Diverticular disease of colon 1 | 15
Dysgraphia 1 | 20
Dyspnea 1 | 76
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Flatfoot 1 | 73
Gait imbalance 1 | 17
Hallux Valgus 1 | 26
High-grade hypermetropia 1 | 24
Hoarseness 1 | 31
Hyperacusis 1 | 11
Hypercalcemia 1 | 59
Hypercalciuria 1 | 27
Hypertension, Renovascular 1 | 10
Hypodontia 1 | 81
Joint stiffness 1 | 84
Keloid 1 | 37
Knee joint valgus deformity 1 | 56
Kyphosis deformity of spine 1 | 114
Lordosis 1 | 54
Malformation of the neck 1 | 19
Malocclusion 1 | 57
Mitral Valve Prolapse Syndrome 1 | 39
Mitral valve insufficiency 1 | 49
Nephroblastoma 1 | 51
Neuro-degenerative disease 1 | 43
Pain 1 | 103
Paralysed 1 | 42
Pelvic kidney 1 | 10
Periorbital edema 1 | 13
Pulmonary Stenosis 1 | 45
Sloping shoulders 1 | 21
Supravalvular aortic stenosis 1 | 12
Williams Syndrome 1 | 10
Williams-Beuren syndrome 1 | 50
obsessive-compulsive disorder 1 | 61

Tissue

Endocrine System 11 | 18,159
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 9 | 12,091
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of actin f... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM domain kinase 1 LIMK1 Tchem Kinase -2.28919 187.7 664
Profilin-3 PFN3 Tdark Non-IDG -0.89066 8.08 8
Profilin-2 PFN2 Tbio Non-IDG -1.95013 88.9 212
Pleckstrin PLEK Tbio Non-IDG -3.00624 743.7 290
Villin-1 VIL1 Tbio Non-IDG -2.20137 162.5 349
Synaptopodin 2-like protein SYNPO2L Tdark Non-IDG -0.17017 1.29 45
Synaptopodin-2 SYNPO2 Tbio Non-IDG -1.31714 27.9 42
DNA-binding protein inhibitor ID-1 ID1 Tbio Transcription Factor -2.62261 440.3 311
Switch-associated protein 70 SWAP70 Tbio Non-IDG -1.37688 29.6 301
Synaptopodin SYNPO Tbio Non-IDG -2.17670 132.7 191