Development Level

Tbio 25 | 11,445
Tchem 10 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal vibrissa morphology 2 | 25
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
increased startle reflex 2 | 112
limb grasping 2 | 41
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye anterior chamber ... 1 | 9
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating glucose ... 1 | 24
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 28 | 11,493
ovarian cancer 24 | 8,520
osteosarcoma 20 | 7,950
medulloblastoma, large-cell 19 | 6,241
Cancer 18 | 2,499
glioblastoma 18 | 5,792
Breast cancer 17 | 3,578
lung cancer 17 | 4,740
psoriasis 16 | 6,694
Astrocytoma, Pilocytic 15 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
invasive ductal carcinoma 14 | 2,951
atypical teratoid / rhabdoid tumor 13 | 5,112
Intellectual disability 12 | 1,016
interstitial cystitis 12 | 2,312
lung adenocarcinoma 12 | 2,716
astrocytic glioma 11 | 2,597
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
juvenile dermatomyositis 10 | 1,187
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
subependymal giant cell astrocytoma 10 | 2,287
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
acute quadriplegic myopathy 9 | 1,158
adult high grade glioma 9 | 3,801
breast carcinoma 9 | 1,638
oligodendroglioma 9 | 2,850
spina bifida 9 | 1,074
Breast Neoplasms 8 | 445
Kidney cancer 8 | 2,613
Mammary Neoplasms 8 | 425
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
tuberculosis 8 | 2,010
Cognitive delay 7 | 608
Duchenne muscular dystrophy 7 | 601
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Pick disease 7 | 1,894
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
lung carcinoma 7 | 2,843
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
ulcerative colitis 7 | 1,819
Amyotrophic lateral sclerosis 6 | 451
Epilepsy 6 | 792
cutaneous lupus erythematosus 6 | 1,057
pediatric high grade glioma 6 | 1,064
Bilateral fifth finger clinodactyly 5 | 110
Brachydactyly 5 | 156
Cryptorchidism 5 | 296
Curvature of little finger 5 | 110
Down syndrome 5 | 499
Liver cancer 5 | 604
Short stature 5 | 531
Small head 5 | 374
group 4 medulloblastoma 5 | 1,855
nasopharyngeal carcinoma 5 | 1,058
posterior fossa group A ependymoma 5 | 468
primary Sjogren syndrome 5 | 735
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Cleft Lip 4 | 141
Cleft Palate 4 | 271
Decreased projection of midface 4 | 105
Dilated ventricles (finding) 4 | 121
Downward slant of palpebral fissure 4 | 158
Hypoplastic mandible condyle 4 | 275
Hypotrophic malar bone 4 | 129
Hypotrophic midface 4 | 105
Liver Cirrhosis, Experimental 4 | 769
Malar flattening 4 | 129
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Midface retrusion 4 | 105
Muscle hypotonia 4 | 571
Orbital separation excessive 4 | 244
Osteoporosis 4 | 363
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Seizures 4 | 596
Small midface 4 | 105
Strabismus 4 | 270
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807

Tissue

Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Blood and immune system 34 | 16,909
Cardiovascular System 33 | 15,192
Respiratory system 33 | 16,393

Target Family

Non-IDG 20 | 12,091
Enzyme 7 | 4,145
Transcription Factor 5 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

positive regulation of Wnt sig... 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
R-spondin-4 RSPO4 Tbio Non-IDG -1.45244 28.7 66
DEP domain-containing protein 1B DEPDC1B Tbio Non-IDG -0.81968 7.18 94
Extracellular sulfatase Sulf-2 SULF2 Tbio Enzyme -1.74398 67.0 221
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Dapper homolog 1 DACT1 Tbio Non-IDG -1.86707 79.6 106
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Methyl-CpG-binding domain protein 2 MBD2 Tchem Transcription Factor -1.74971 47.7 297
Transcription factor SOX-4 SOX4 Tbio Transcription Factor -2.22104 164.2 211
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643