Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal retinal inner nuclear... 1 | 8
abnormal testis morphology 1 | 43
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased eosinophil cell numb... 1 | 24
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged lymph nodes 1 | 37
preweaning lethality, incomple... 1 | 499

Disease

Cancer 10 | 2,499
Carcinoma 10 | 11,493
ovarian cancer 8 | 8,520
atypical teratoid / rhabdoid tumor 7 | 5,112
lung cancer 7 | 4,740
Breast cancer 6 | 3,578
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Cleft Palate 5 | 271
Colorectal Neoplasms 5 | 243
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
pancreatic cancer 5 | 2,398
Anemia 4 | 365
Hypertensive disease 4 | 292
Orbital separation excessive 4 | 244
Pulmonary Fibrosis 4 | 106
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
Aortic Valve Insufficiency 3 | 40
Cleft Lip 3 | 141
Cleft uvula 3 | 27
Coronary artery disease 3 | 268
Exophthalmos 3 | 112
Hereditary hemorrhagic telangiectasia 3 | 13
Hypotrophic malar bone 3 | 129
Increase in blood pressure 3 | 119
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Malar flattening 3 | 129
Osteoarthritis 3 | 184
Pick disease 3 | 1,894
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Abdominal Pain 2 | 98
Acquired scoliosis 2 | 281
Adenoma 2 | 167
Arachnodactyly 2 | 49
Atherosclerosis 2 | 291
Blue sclera 2 | 32
Brachydactyly 2 | 156
Breast Neoplasms 2 | 445
Byzanthine arch palate 2 | 194
Cardiomegaly 2 | 116
Cerebrovascular disease 2 | 238
Chest Pain 2 | 38
Cholecystitis 2 | 18
Class III malocclusion 2 | 78
Congenital deafness 2 | 185
Craniofacial Abnormalities 2 | 151
Deafness 2 | 198
Decreased joint mobility 2 | 53
Degenerative polyarthritis 2 | 115
Failure to gain weight 2 | 365
Globe disease 2 | 67
Hearing Loss, Partial 2 | 185
Hemoglobin low 2 | 124
Holoprosencephaly 2 | 56
Hypertension 2 | 396
Hypertrophy of lower jaw 2 | 78
Hypoalbuminemia 2 | 24
Increased size of mandible 2 | 78
Inflammation 2 | 120
Juvenile polyposis syndrome 2 | 7
Kidney Diseases 2 | 114
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Mammary Neoplasms 2 | 425
Mandibular hyperplasia 2 | 78
Muscular Diseases 2 | 27
Myopathy 2 | 185
Neurodegenerative disease 2 | 414
Osteoporosis 2 | 363
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pediatric failure to thrive 2 | 365
Pneumonia 2 | 174
Tall stature 2 | 34
active Crohn's disease 2 | 922
hearing impairment 2 | 199
mandibular excess (physical finding) 2 | 78
posterior fossa group A ependymoma 2 | 468

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 8 | 12,091
Kinase 2 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

positive regulation of SMAD pr... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Nuclear pore complex protein Nup93 NUP93 Tbio Non-IDG -1.35565 22.2 62
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Disabled homolog 2 DAB2 Tbio Non-IDG -2.26146 184.8 239
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.31332 2140.4 983
Nodal homolog NODAL Tbio Non-IDG -3.00545 981.7 245
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
RNA-binding protein with multiple splicing RBPMS Tbio Non-IDG -2.12771 131.9 266