Development Level

Tbio 26 | 11,445
Tchem 4 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal lens morphology 2 | 81
decreased vertical activity 2 | 208
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal eating behavior 1 | 1
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal forced expiratory flo... 1 | 1
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
cataract 1 | 92
corneal opacity 1 | 32
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased tidal volume 1 | 1
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97

Disease

Carcinoma 19 | 11,493
osteosarcoma 19 | 7,950
psoriasis 19 | 6,694
ovarian cancer 18 | 8,520
glioblastoma 17 | 5,792
medulloblastoma, large-cell 17 | 6,241
adult high grade glioma 16 | 3,801
ependymoma 15 | 4,679
lung cancer 14 | 4,740
Breast cancer 13 | 3,578
Astrocytoma, Pilocytic 12 | 3,081
Cancer 12 | 2,499
atypical teratoid / rhabdoid tumor 12 | 5,112
astrocytic glioma 11 | 2,597
lung carcinoma 10 | 2,843
oligodendroglioma 10 | 2,850
primitive neuroectodermal tumor 10 | 3,035
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
lung adenocarcinoma 9 | 2,716
subependymal giant cell astrocytoma 9 | 2,287
group 3 medulloblastoma 8 | 4,104
malignant mesothelioma 8 | 3,232
Cleft Palate 7 | 271
Kidney cancer 7 | 2,613
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
Craniofacial Abnormalities 6 | 151
cystic fibrosis 6 | 1,696
interstitial cystitis 6 | 2,312
Short stature 5 | 531
adrenocortical carcinoma 5 | 1,428
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Acquired scoliosis 4 | 281
Bipolar Disorder 4 | 666
Carcinoma, Pancreatic Ductal 4 | 20
Cataract 4 | 297
Crohn's disease 4 | 321
Curvature of spine 4 | 282
Failure to gain weight 4 | 365
Lymphoid leukemia 4 | 160
Pediatric failure to thrive 4 | 365
Strabismus 4 | 270
Syndactyly 4 | 88
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
non-small cell lung carcinoma 4 | 317
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
Adenoid Cystic Carcinoma 3 | 99
Alagille syndrome 3 | 15
Alzheimer's disease 3 | 658
Anemia 3 | 365
Brachydactyly 3 | 156
Byzanthine arch palate 3 | 194
Carcinoma, Adenoid Cystic 3 | 99
Colonic Neoplasms 3 | 142
Concave bridge of nose 3 | 195
Congenital Heart Defects 3 | 58
Deafness 3 | 198
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Heart Defects, Congenital 3 | 37
Heart disease 3 | 306
Immune system cancer 3 | 140
Liver disease 3 | 237
Lung Neoplasms 3 | 232
Multiple myeloma 3 | 1,332
Nervous System Diseases 3 | 53
Prostate cancer 3 | 175
RENAL ADYSPLASIA 3 | 25
Renal dysplasia 3 | 28
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
Sparse hair 3 | 59
Tetralogy of Fallot 3 | 63
Thin, sparse hair 3 | 59
Uterine Cervical Neoplasm 3 | 25
Uterine Cervical Neoplasms 3 | 26
Ventricular Septal Defects 3 | 119
Waldenstrons macroglobulinemia 3 | 765
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
nervous system disorder 3 | 53
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
posterior fossa group B ependymoma 3 | 416

Tissue

Endocrine System 35 | 18,159
Nervous System 35 | 16,725
Female tissues 34 | 17,400
Respiratory system 34 | 16,393
Urinary Tract 34 | 16,678
Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Liver and Pancreas 32 | 16,750
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 19 | 12,091
Transcription Factor 8 | 1,400
Enzyme 4 | 4,145
Kinase 3 | 634
Transporter 1 | 473

GO Process

positive regulation of Notch s... 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-N-acetylglucosaminyltransferase radical fringe RFNG Tdark Enzyme -0.37913 1.57 92
Mesoderm posterior protein 1 MESP1 Tbio Transcription Factor -1.38536 26.8 208
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
Contactin-6 CNTN6 Tbio Non-IDG -2.09155 109.6 79
Tetraspanin-14 TSPAN14 Tdark Non-IDG -0.21804 1.22 39
GS homeobox 2 GSX2 Tbio Transcription Factor -1.56813 38.8 92
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098