Development Level

Tbio 82 | 11,445
Tchem 46 | 1,598
Tclin 11 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal lens morphology 2 | 81
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased red blood cell distr... 1 | 41
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased eosinophil cell numb... 1 | 11
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
scaly skin 1 | 4
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 88 | 11,493
ovarian cancer 76 | 8,520
osteosarcoma 74 | 7,950
psoriasis 70 | 6,694
glioblastoma 67 | 5,792
lung cancer 65 | 4,740
Cancer 58 | 2,499
medulloblastoma, large-cell 45 | 6,241
lung carcinoma 41 | 2,843
tuberculosis 41 | 2,010
ependymoma 40 | 4,679
atypical teratoid / rhabdoid tumor 39 | 5,112
non-small cell lung cancer 37 | 2,890
subependymal giant cell astrocytoma 37 | 2,287
adult high grade glioma 36 | 3,801
malignant mesothelioma 34 | 3,232
pancreatic cancer 33 | 2,398
ulcerative colitis 32 | 1,819
Breast cancer 31 | 3,578
lung adenocarcinoma 31 | 2,716
Rheumatoid arthritis 30 | 1,191
Astrocytoma, Pilocytic 29 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
diabetes mellitus 28 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
invasive ductal carcinoma 28 | 2,951
Kidney cancer 27 | 2,613
cystic fibrosis 26 | 1,696
group 3 medulloblastoma 26 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
cutaneous lupus erythematosus 25 | 1,057
interstitial cystitis 25 | 2,312
oligodendroglioma 25 | 2,850
pituitary cancer 23 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
Autosomal recessive predisposition 21 | 1,442
Schizophrenia 21 | 1,160
astrocytic glioma 21 | 2,597
Bipolar Disorder 19 | 666
dermatomyositis 19 | 966
Arthritis 18 | 290
Atherosclerosis 18 | 291
astrocytoma 18 | 1,146
juvenile dermatomyositis 18 | 1,187
primitive neuroectodermal tumor 18 | 3,035
Hypertension 17 | 396
Pick disease 17 | 1,894
Asthma 16 | 385
Kidney disease 16 | 430
Multiple myeloma 16 | 1,332
Obesity 16 | 678
Pneumonia 16 | 174
group 4 medulloblastoma 16 | 1,855
Liver Cirrhosis, Experimental 15 | 769
Waldenstrons macroglobulinemia 15 | 765
acute quadriplegic myopathy 15 | 1,158
Atopic dermatitis 14 | 952
Coronary artery disease 14 | 268
Hypersensitivity reaction type II disease 14 | 253
Hypertensive disease 14 | 292
Inflammatory bowel disease 14 | 151
Cerebrovascular disease 13 | 238
Immunologic Deficiency Syndromes 13 | 113
Influenza 13 | 142
Osteoporosis 13 | 363
Prostatic Neoplasms 13 | 495
primary pancreatic ductal adenocarcinoma 13 | 1,109
Allergic hypersensitivity disease 12 | 126
Anemia 12 | 365
Inflammation 12 | 120
Reperfusion Injury 12 | 86
acute myeloid leukemia 12 | 783
breast carcinoma 12 | 1,638
colon cancer 12 | 1,478
gastric carcinoma 12 | 807
nasopharyngeal carcinoma 12 | 1,058
Breast Neoplasms 11 | 445
Depressive disorder 11 | 409
Dermatitis 11 | 157
Malaria 11 | 160
Melanoma 11 | 711
Multiple Sclerosis 11 | 540
ductal carcinoma in situ 11 | 1,745
mucosa-associated lymphoid tissue lymphoma 11 | 484
primary Sjogren syndrome 11 | 735
Alzheimer's disease 10 | 658
Arthritis, Rheumatoid 10 | 174
Hyperglycemia 10 | 137
Intellectual disability 10 | 1,016
Liver disease 10 | 237
Mammary Neoplasms 10 | 425
Meningitis 10 | 67
Seizures 10 | 596
active ulcerative colitis 10 | 764
adrenocortical carcinoma 10 | 1,428
aldosterone-producing adenoma 10 | 665
hepatocellular carcinoma 10 | 547
pancreatic carcinoma 10 | 562
periodontitis 10 | 293
Crohn's disease 9 | 321

Tissue

Skin and soft tissues 140 | 17,230
Digestive Tract 139 | 17,369
Endocrine System 139 | 18,159
Liver and Pancreas 139 | 16,750
Urinary Tract 139 | 16,678
Blood and immune system 138 | 16,909
Female tissues 138 | 17,400
Respiratory system 138 | 16,393
Male tissues 137 | 17,142
Nervous System 136 | 16,725
Cardiovascular System 133 | 15,192

Target Family

Non-IDG 77 | 12,091
Kinase 31 | 634
Enzyme 26 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

positive regulation of NF-kapp... 140 | 140
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Probable E3 ubiquitin-protein ligase MID2 MID2 Tbio Enzyme -2.49198 303.4 152
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370