Development Level

Tbio 46 | 11,651
Tclin 22 | 612
Tchem 17 | 1,388
Tdark 2 | 6,593

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased hematocrit 2 | 46
decreased prepulse inhibition 2 | 82
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
cleft palate 1 | 8
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
fused cornea and lens 1 | 5
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased IgG2b level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
iris synechia 1 | 3
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 57 | 11,493
Cancer 44 | 2,499
ovarian cancer 44 | 8,520
psoriasis 44 | 6,694
glioblastoma 41 | 5,792
atypical teratoid / rhabdoid tumor 38 | 5,112
malignant mesothelioma 38 | 3,232
lung cancer 37 | 4,740
osteosarcoma 36 | 7,950
medulloblastoma, large-cell 35 | 6,241
ependymoma 30 | 4,679
Breast cancer 28 | 3,578
Astrocytoma, Pilocytic 26 | 3,081
group 3 medulloblastoma 26 | 4,104
invasive ductal carcinoma 25 | 2,951
non-small cell lung cancer 24 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
lung adenocarcinoma 23 | 2,716
lung carcinoma 23 | 2,843
astrocytic glioma 22 | 2,597
oligodendroglioma 22 | 2,850
pituitary cancer 22 | 1,972
adult high grade glioma 21 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
interstitial cystitis 20 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
primitive neuroectodermal tumor 20 | 3,035
Breast Neoplasms 19 | 445
Kidney cancer 19 | 2,613
Schizophrenia 19 | 1,160
breast carcinoma 19 | 1,638
Mammary Neoplasms 18 | 425
subependymal giant cell astrocytoma 18 | 2,287
diabetes mellitus 17 | 1,728
pancreatic cancer 17 | 2,398
ulcerative colitis 17 | 1,819
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
Obesity 15 | 678
Alzheimer's disease 14 | 658
Bipolar Disorder 14 | 666
Depressive disorder 14 | 409
Epilepsy 14 | 792
adrenocortical carcinoma 14 | 1,428
cystic fibrosis 14 | 1,696
ductal carcinoma in situ 14 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Mental Depression 13 | 333
Osteoporosis 13 | 363
Parkinson's disease 13 | 392
Polycystic ovary syndrome 13 | 360
Prostatic Neoplasms 13 | 495
Rheumatoid arthritis 13 | 1,191
Seizures 13 | 596
Stomach Neoplasms 13 | 300
colon cancer 13 | 1,478
Cerebrovascular disease 12 | 238
Intellectual disability 12 | 1,016
pediatric high grade glioma 12 | 1,064
Arthritis 11 | 290
Hypertension 11 | 396
Liver Cirrhosis, Experimental 11 | 769
Short stature 11 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
group 4 medulloblastoma 11 | 1,855
tuberculosis 11 | 2,010
Asthma 10 | 385
Atherosclerosis 10 | 291
Autosomal recessive predisposition 10 | 1,442
Coronary artery disease 10 | 268
Duchenne muscular dystrophy 10 | 601
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
Renal Cell Carcinoma 10 | 214
primary pancreatic ductal adenocarcinoma 10 | 1,109
Autistic Disorder 9 | 364
Cleft Palate 9 | 271
Cryptorchidism 9 | 296
Diabetes Mellitus, Experimental 9 | 108
Heart disease 9 | 306
Hypoglycemia 9 | 152
Kidney disease 9 | 430
Liver disease 9 | 237
Muscle hypotonia 9 | 571
Nerve Degeneration 9 | 121
Peripheral vascular disease 9 | 87
cutaneous lupus erythematosus 9 | 1,057
gastric carcinoma 9 | 807
juvenile dermatomyositis 9 | 1,187
Atopic dermatitis 8 | 952
Down syndrome 8 | 499
Myocardial Ischemia 8 | 169
Orbital separation excessive 8 | 244
Small head 8 | 374
astrocytoma 8 | 1,146
esophageal adenocarcinoma 8 | 737

Tissue

Endocrine System 84 | 18,159
Digestive Tract 83 | 17,369
Female tissues 83 | 17,400
Nervous System 83 | 16,725
Skin and soft tissues 83 | 17,230
Blood and immune system 82 | 16,909
Liver and Pancreas 82 | 16,750
Urinary Tract 79 | 16,678
Male tissues 78 | 17,142
Respiratory system 78 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 43 | 12,091
Kinase 18 | 634
GPCR 14 | 408
Enzyme 8 | 4,145
Transcription Factor 3 | 1,400
Nuclear Receptor 1 | 48

GO Process

positive regulation of MAPK ca... 87 | 87
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Fc receptor-like protein 3 FCRL3 Tbio Non-IDG -1.79020 70.8 83
Neudesin NENF Tbio Non-IDG -1.33987 22.4 117
Cell adhesion molecule-related/down-regulated by oncogenes CDON Tbio Non-IDG -2.67247 471.8 128
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.35760 2176.5 510
Dual specificity protein phosphatase 19 DUSP19 Tdark Enzyme -0.55139 4.50 122
Insulin INS Tbio Non-IDG -5.17849 146933.7 2197
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058