Development Level

Tbio 42 | 10,625
Tclin 18 | 602
Tchem 17 | 1,890
Tdark 3 | 7,003

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
decreased T cell number 2 | 31
decreased grip strength 2 | 123
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
increased mean corpuscular vol... 2 | 91
preweaning lethality, incomple... 2 | 260
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal motor learning 1 | 4
abnormal neural tube closure 1 | 37
abnormal retinal vasculature m... 1 | 15
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal urinary bladder morph... 1 | 2
cataract 1 | 26
cleft palate 1 | 6
corneal opacity 1 | 25
decreased CD8-positive, alpha-... 1 | 26
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased lean body mass 1 | 195
decreased prepulse inhibition 1 | 52
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
narrow eye opening 1 | 15
short tibia 1 | 82
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Cancer 44 | 2,346
psoriasis 41 | 6,685
ovarian cancer 39 | 8,484
osteosarcoma 37 | 7,933
glioblastoma 34 | 5,572
lung cancer 34 | 4,466
medulloblastoma, large-cell 33 | 6,234
malignant mesothelioma 31 | 3,162
atypical teratoid / rhabdoid tumor 26 | 4,369
pilocytic astrocytoma 24 | 3,086
lung adenocarcinoma 23 | 2,713
pediatric high grade glioma 23 | 2,712
interstitial cystitis 22 | 2,299
non-small cell lung cancer 22 | 2,798
invasive ductal carcinoma 21 | 2,950
pituitary cancer 21 | 1,972
Breast cancer 20 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
lung carcinoma 19 | 2,844
ulcerative colitis 19 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
oligodendroglioma 18 | 2,849
Carcinoma 17 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
pancreatic cancer 17 | 2,300
Mammary Neoplasms 16 | 410
breast carcinoma 16 | 1,614
primitive neuroectodermal tumor 16 | 3,031
subependymal giant cell astrocytoma 16 | 2,287
diabetes mellitus 15 | 1,663
group 4 medulloblastoma 15 | 1,875
primary pancreatic ductal adenocarcinoma 15 | 1,271
Obesity 14 | 616
adrenocortical carcinoma 14 | 1,427
ependymoma 14 | 2,514
posterior fossa group A ependymoma 14 | 1,511
Prostatic Neoplasms 13 | 471
astrocytic glioma 13 | 2,241
colon cancer 13 | 1,475
Alzheimer's disease 12 | 644
Polycystic Ovary Syndrome 12 | 332
Rheumatoid Arthritis 12 | 1,160
cystic fibrosis 12 | 1,665
ductal carcinoma in situ 12 | 1,745
tuberculosis 12 | 1,557
Atherosclerosis 11 | 275
Kidney disease 11 | 396
gastric carcinoma 11 | 832
group 3 medulloblastoma 11 | 2,254
Autistic Disorder 10 | 320
Liver disease 10 | 219
Osteoporosis 10 | 257
Schizophrenia 10 | 501
Stomach Neoplasms 10 | 282
astrocytoma 10 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
cutaneous lupus erythematosus 10 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Arthritis 9 | 248
Coronary artery disease 9 | 240
Duchenne muscular dystrophy 9 | 602
Heart disease 9 | 279
Liver Cirrhosis 9 | 101
Lung Neoplasms 9 | 171
Parkinson's disease 9 | 364
Renal Cell Carcinoma 9 | 199
primary Sjogren syndrome 9 | 789
sonic hedgehog group medulloblastoma 9 | 1,482
Asthma 8 | 349
Atopic dermatitis 8 | 944
Cerebrovascular disease 8 | 231
Cleft palate 8 | 125
Diabetes Mellitus, Experimental 8 | 106
Hypertension 8 | 287
Myocardial Ischemia 8 | 169
Nerve Degeneration 8 | 73
active Crohn's disease 8 | 918
atypical teratoid/rhabdoid tumor 8 | 1,095
Diabetes Mellitus, Non-Insulin-Dependent 7 | 157
Hamman-Rich syndrome 7 | 35
Hyperinsulinism 7 | 63
Infertility 7 | 163
Spontaneous abortion 7 | 108
adult high grade glioma 7 | 2,148
esophageal adenocarcinoma 7 | 737
non-small cell lung carcinoma 7 | 413
Adenoma 6 | 165
Cleft Lip 6 | 91
Colorectal Neoplasms 6 | 217
Craniofacial Abnormalities 6 | 147
Drug-Induced Liver Injury 6 | 118
Hypersensitivity reaction type II disease 6 | 235
Hypogonadism 6 | 70
Liver carcinoma 6 | 217
Multiple myeloma 6 | 1,327
Papillary thyroid carcinoma 6 | 37
Peripheral vascular disease 6 | 90
Pick disease 6 | 1,893
juvenile dermatomyositis 6 | 1,189
spina bifida 6 | 1,064

Tissue

Blood and immune system 79 | 17,995
Digestive Tract 79 | 18,473
Female tissues 79 | 18,647
Cardiovascular System 78 | 17,958
Endocrine System 78 | 18,512
Liver and Pancreas 78 | 18,136
Male tissues 78 | 17,969
Nervous System 78 | 18,561
Skin and soft tissues 78 | 18,115
Urinary Tract 78 | 18,444
Respiratory system 77 | 17,484

Target Family

Non-IDG 43 | 11,971
Kinase 15 | 634
GPCR 11 | 406
Enzyme 7 | 4,146
Transcription Factor 3 | 1,400
Nuclear Receptor 1 | 48

GO Process

positive regulation of MAPK ca... 80 | 80
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Protein KIBRA WWC1 Tbio Non-IDG -1.88892 84.4 96
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Cell adhesion molecule-related/down-regulated by oncogenes CDON Tbio Non-IDG -2.61357 437.0 112
Alpha-1B adrenergic receptor ADRA1B Tclin GPCR -2.30072 198.4 327
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.59556 4267.5 575
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.16676 150.4 223
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
Beta-3 adrenergic receptor ADRB3 Tclin GPCR -2.70027 550.2 236