Development Level

Tbio 22 | 11,445
Tchem 19 | 1,598
Tclin 16 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
abnormal embryo size 2 | 220
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 41 | 11,493
ovarian cancer 40 | 8,520
Cancer 38 | 2,499
osteosarcoma 37 | 7,950
lung cancer 31 | 4,740
Breast cancer 30 | 3,578
psoriasis 30 | 6,694
malignant mesothelioma 27 | 3,232
atypical teratoid / rhabdoid tumor 25 | 5,112
glioblastoma 25 | 5,792
invasive ductal carcinoma 24 | 2,951
ependymoma 23 | 4,679
Astrocytoma, Pilocytic 21 | 3,081
medulloblastoma, large-cell 20 | 6,241
non-small cell lung cancer 20 | 2,890
pancreatic cancer 20 | 2,398
cystic fibrosis 19 | 1,696
Kidney cancer 18 | 2,613
adult high grade glioma 18 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
ulcerative colitis 18 | 1,819
interstitial cystitis 17 | 2,312
lung adenocarcinoma 17 | 2,716
diabetes mellitus 16 | 1,728
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung carcinoma 15 | 2,843
oligodendroglioma 15 | 2,850
primitive neuroectodermal tumor 15 | 3,035
astrocytic glioma 14 | 2,597
Breast Neoplasms 13 | 445
Liver Cirrhosis, Experimental 13 | 769
Mammary Neoplasms 13 | 425
Schizophrenia 13 | 1,160
ductal carcinoma in situ 13 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
tuberculosis 13 | 2,010
Depressive disorder 12 | 409
Heart disease 12 | 306
Kidney disease 12 | 430
Rheumatoid arthritis 12 | 1,191
breast carcinoma 12 | 1,638
Autosomal recessive predisposition 11 | 1,442
Atherosclerosis 10 | 291
Epilepsy 10 | 792
Hypertension 10 | 396
Prostatic Neoplasms 10 | 495
group 4 medulloblastoma 10 | 1,855
nasopharyngeal carcinoma 10 | 1,058
pituitary cancer 10 | 1,972
Asthma 9 | 385
Coronary artery disease 9 | 268
Lung Neoplasms 9 | 232
Neoplasm Metastasis 9 | 168
Pulmonary Fibrosis 9 | 106
Renal Cell Carcinoma 9 | 214
Seizures 9 | 596
Adenocarcinoma 8 | 122
Anemia 8 | 365
Carcinoma, Hepatocellular 8 | 228
Endometriosis 8 | 540
Liver carcinoma 8 | 240
Major Depressive Disorder 8 | 301
Melanoma 8 | 711
adrenocortical carcinoma 8 | 1,428
colon cancer 8 | 1,478
primary pancreatic ductal adenocarcinoma 8 | 1,109
subependymal giant cell astrocytoma 8 | 2,287
Adenoma 7 | 167
Arthritis 7 | 290
Atopic dermatitis 7 | 952
Autistic Disorder 7 | 364
Bipolar Disorder 7 | 666
Cardiomegaly 7 | 116
Cerebrovascular disease 7 | 238
Colonic Neoplasms 7 | 142
Exanthem 7 | 37
Hypertensive disease 7 | 292
Lung disease 7 | 142
Mammary Neoplasms, Experimental 7 | 154
Mood Disorders 7 | 184
Neutropenia 7 | 72
Parkinson's disease 7 | 392
Pick disease 7 | 1,894
Vascular disease 7 | 319
acute quadriplegic myopathy 7 | 1,158
Alzheimer's disease 6 | 658
Arthritis, Rheumatoid 6 | 174
Hypersensitivity reaction type II disease 6 | 253
Inflammatory bowel disease 6 | 151
Mental Depression 6 | 333
Myocardial Ischemia 6 | 169
Stomach Neoplasms 6 | 300
Unipolar Depression 6 | 250
cutaneous lupus erythematosus 6 | 1,057
fibroadenoma 6 | 559
gastric carcinoma 6 | 807
medulloblastoma 6 | 720
mucosa-associated lymphoid tissue lymphoma 6 | 484

Tissue

Blood and immune system 57 | 16,909
Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Female tissues 57 | 17,400
Respiratory system 57 | 16,393
Liver and Pancreas 56 | 16,750
Male tissues 56 | 17,142
Skin and soft tissues 56 | 17,230
Urinary Tract 56 | 16,678
Nervous System 53 | 16,725
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 29 | 12,091
Kinase 14 | 634
Enzyme 10 | 4,145
GPCR 3 | 408
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

positive regulation of MAP kin... 58 | 58
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Melanoma-associated antigen D1 MAGED1 Tbio Non-IDG -1.55131 46.3 245
Teneurin-1 TENM1 Tbio Non-IDG -1.81805 61.8 60
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.89822 84.6 146
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.35296 2270.4 122
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574