Development Level

Tbio 21 | 11,445
Tchem 10 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
increased blood urea nitrogen ... 2 | 48
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
curly tail 1 | 1
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hydrometra 1 | 53
hydrops fetalis 1 | 1
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating insulin ... 1 | 3
increased circulating triglyce... 1 | 42
kinked tail 1 | 2
mammalian phenotype 1 | 17
microphthalmia 1 | 26
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 28 | 11,493
lung cancer 17 | 4,740
psoriasis 17 | 6,694
ovarian cancer 16 | 8,520
Cancer 15 | 2,499
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 14 | 5,112
osteosarcoma 14 | 7,950
Kidney cancer 13 | 2,613
non-small cell lung cancer 13 | 2,890
glioblastoma 12 | 5,792
malignant mesothelioma 12 | 3,232
cystic fibrosis 11 | 1,696
group 3 medulloblastoma 11 | 4,104
lung carcinoma 11 | 2,843
ependymoma 10 | 4,679
Breast cancer 9 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Astrocytoma, Pilocytic 8 | 3,081
interstitial cystitis 8 | 2,312
lung adenocarcinoma 8 | 2,716
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
ulcerative colitis 7 | 1,819
Pick disease 6 | 1,894
adult high grade glioma 6 | 3,801
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
spina bifida 6 | 1,074
Melanoma 5 | 711
Rheumatoid arthritis 5 | 1,191
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
cutaneous lupus erythematosus 5 | 1,057
esophageal adenocarcinoma 5 | 737
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Amyotrophic lateral sclerosis 4 | 451
Arthritis 4 | 290
Breast Neoplasms 4 | 445
Inflammation 4 | 120
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms 4 | 425
Osteoporosis 4 | 363
Prostatic Neoplasms 4 | 495
Vascular disease 4 | 319
group 4 medulloblastoma 4 | 1,855
pancreatic cancer 4 | 2,398
Allergic hypersensitivity disease 3 | 126
Arthritis, Rheumatoid 3 | 174
Asthma 3 | 385
Atherosclerosis 3 | 291
Autosomal recessive predisposition 3 | 1,442
Cardiomyopathies 3 | 110
Coronary artery disease 3 | 268
Diabetes Mellitus, Experimental 3 | 108
Hyperalgesia 3 | 83
Hyperglycemia 3 | 137
Hypoplastic mandible condyle 3 | 275
Kidney disease 3 | 430
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Pain 3 | 103
Parkinson Disease 3 | 64
Parkinson's disease 3 | 392
Robinow syndrome 3 | 11
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
fibroadenoma 3 | 559
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
primary Sjogren syndrome 3 | 735
Anemia 2 | 365
Brain Ischemia 2 | 110
Cerebrovascular disease 2 | 238
Endometrial cancer 2 | 311
Heart disease 2 | 306
Hypertension 2 | 396
Inflammatory bowel disease 2 | 151
Leishmaniasis 2 | 47
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Major Depressive Disorder 2 | 301
Malaria 2 | 160
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Neoplasm Invasiveness 2 | 161
Pectus excavatum 2 | 100
Reperfusion Injury 2 | 86
Status Epilepticus 2 | 98
Unipolar Depression 2 | 250
medulloblastoma 2 | 720

Tissue

Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Nervous System 33 | 16,725
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 18 | 12,091
Kinase 10 | 634
GPCR 4 | 408
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

positive regulation of JUN kin... 34 | 34
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
Mitogen-activated protein kinase kinase kinase 4 MAP3K4 Tbio Kinase -1.49704 31.8 244
Mitogen-activated protein kinase kinase kinase 10 MAP3K10 Tchem Kinase -1.20048 15.1 221
Rho guanine nucleotide exchange factor 5 ARHGEF5 Tbio Non-IDG -0.48804 5.75 249
SAM and SH3 domain-containing protein 1 SASH1 Tbio Non-IDG -1.50284 36.9 182
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
FYVE, RhoGEF and PH domain-containing protein 2 FGD2 Tbio Non-IDG 0.00000 51
Serine/threonine-protein kinase TAO3 TAOK3 Tchem Kinase -2.62072 379.0 325
Frizzled-8 FZD8 Tbio GPCR -1.64874 42.5 233
Advanced glycosylation end product-specific receptor AGER Tchem Non-IDG -2.29145 187.3 589