Development Level

Tbio 108 | 11,445
Tchem 41 | 1,598
Tclin 9 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 10 | 979
decreased vertical activity 6 | 208
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
enlarged heart 4 | 210
abnormal behavior 3 | 298
abnormal lens morphology 3 | 81
decreased body weight 3 | 161
decreased circulating triglyce... 3 | 79
increased total body fat amoun... 3 | 134
tremors 3 | 39
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
decreased monocyte cell number 2 | 8
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged spleen 2 | 41
hypoactivity 2 | 132
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased startle reflex 2 | 112
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
improved glucose tolerance 1 | 79
increased basophil cell number 1 | 7
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
limb grasping 1 | 41
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
scaly skin 1 | 4
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

ovarian cancer 99 | 8,520
Carcinoma 96 | 11,493
osteosarcoma 91 | 7,950
glioblastoma 82 | 5,792
psoriasis 78 | 6,694
lung cancer 70 | 4,740
Cancer 60 | 2,499
medulloblastoma, large-cell 51 | 6,241
ependymoma 49 | 4,679
lung carcinoma 47 | 2,843
atypical teratoid / rhabdoid tumor 45 | 5,112
adult high grade glioma 44 | 3,801
Astrocytoma, Pilocytic 42 | 3,081
subependymal giant cell astrocytoma 42 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
Breast cancer 39 | 3,578
malignant mesothelioma 39 | 3,232
tuberculosis 39 | 2,010
ulcerative colitis 37 | 1,819
pancreatic cancer 35 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
non-small cell lung cancer 33 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
oligodendroglioma 29 | 2,850
pituitary cancer 29 | 1,972
invasive ductal carcinoma 28 | 2,951
lung adenocarcinoma 28 | 2,716
astrocytic glioma 27 | 2,597
cutaneous lupus erythematosus 27 | 1,057
cystic fibrosis 27 | 1,696
group 3 medulloblastoma 27 | 4,104
interstitial cystitis 27 | 2,312
primitive neuroectodermal tumor 27 | 3,035
Rheumatoid arthritis 26 | 1,191
juvenile dermatomyositis 25 | 1,187
Autosomal recessive predisposition 23 | 1,442
Liver Cirrhosis, Experimental 23 | 769
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
diabetes mellitus 22 | 1,728
primary pancreatic ductal adenocarcinoma 22 | 1,109
astrocytoma 21 | 1,146
group 4 medulloblastoma 21 | 1,855
Kidney cancer 20 | 2,613
breast carcinoma 20 | 1,638
colon cancer 19 | 1,478
Atopic dermatitis 18 | 952
Pick disease 18 | 1,894
active Crohn's disease 18 | 922
active ulcerative colitis 18 | 764
dermatomyositis 18 | 966
adrenocortical carcinoma 17 | 1,428
esophageal adenocarcinoma 17 | 737
Multiple Sclerosis 16 | 540
Multiple myeloma 16 | 1,332
Alzheimer's disease 15 | 658
Breast Neoplasms 15 | 445
nasopharyngeal carcinoma 15 | 1,058
Hypertension 14 | 396
Mammary Neoplasms 14 | 425
acute myeloid leukemia 14 | 783
acute quadriplegic myopathy 14 | 1,158
ductal carcinoma in situ 14 | 1,745
mucosa-associated lymphoid tissue lymphoma 14 | 484
spina bifida 14 | 1,074
Crohn's disease 13 | 321
Waldenstrons macroglobulinemia 13 | 765
gastric carcinoma 13 | 807
primary Sjogren syndrome 13 | 735
Arthritis 12 | 290
Melanoma 12 | 711
Prostatic Neoplasms 12 | 495
Asthma 11 | 385
Bipolar Disorder 11 | 666
Down syndrome 11 | 499
Hypertensive disease 11 | 292
Influenza 11 | 142
Kidney disease 11 | 430
Neurodegenerative disease 11 | 414
Schizophrenia 11 | 1,160
Duchenne muscular dystrophy 10 | 601
Hypersensitivity reaction type II disease 10 | 253
Inflammatory bowel disease 10 | 151
Pneumonia 10 | 174
Stomach Neoplasms 10 | 300
hepatocellular carcinoma 10 | 547
pediatric high grade glioma 10 | 1,064
sarcoidosis 10 | 370
Anemia 9 | 365
Chronic Lymphocytic Leukemia 9 | 262
Inflammation 9 | 120
Intellectual disability 9 | 1,016
Obesity 9 | 678
Vascular disease 9 | 319
aldosterone-producing adenoma 9 | 665
medulloblastoma 9 | 720
pancreatic carcinoma 9 | 562
Arthritis, Rheumatoid 8 | 174
Dull intelligence 8 | 645
Poor school performance 8 | 645
fibroadenoma 8 | 559

Tissue

Blood and immune system 162 | 16,909
Digestive Tract 162 | 17,369
Endocrine System 162 | 18,159
Female tissues 162 | 17,400
Liver and Pancreas 162 | 16,750
Respiratory system 162 | 16,393
Skin and soft tissues 162 | 17,230
Urinary Tract 162 | 16,678
Male tissues 161 | 17,142
Nervous System 160 | 16,725
Cardiovascular System 157 | 15,192

Target Family

Non-IDG 93 | 12,091
Enzyme 33 | 4,145
Kinase 22 | 634
GPCR 6 | 408
Transcription Factor 4 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Process

positive regulation of I-kappa... 164 | 164
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Probable E3 ubiquitin-protein ligase MID2 MID2 Tbio Enzyme -2.49198 303.4 152
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.67951 5.49 37
Secreted and transmembrane protein 1 SECTM1 Tbio Non-IDG -0.82741 7.99 65
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Vesicle transport protein GOT1B GOLT1B Tdark Non-IDG -0.71600 5.85 47
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Bone marrow stromal antigen 2 BST2 Tbio Non-IDG -2.59753 424.5 464