Development Level

Tbio 100 | 11,651
Tchem 56 | 1,388
Tclin 36 | 612
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Complete... 2 | 25
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 14 | 979
decreased total body fat amoun... 6 | 207
enlarged heart 5 | 210
abnormal behavior 4 | 298
abnormal gait 4 | 69
decreased lean body mass 4 | 135
increased circulating alkaline... 4 | 122
increased total body fat amoun... 4 | 134
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal seminal vesicle morph... 3 | 114
decreased fasted circulating g... 3 | 65
decreased lymphocyte cell numb... 3 | 83
impaired glucose tolerance 3 | 75
increased circulating choleste... 3 | 66
abnormal behavioral response t... 2 | 66
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal locomotor behavior 2 | 24
absent startle reflex 2 | 24
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased circulating iron lev... 2 | 30
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
limb grasping 2 | 41
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased pulmonary respirator... 1 | 5
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged stomach 1 | 2
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
iris synechia 1 | 3
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
short tibia 1 | 97
small thymus 1 | 16

Disease

Carcinoma 109 | 11,493
Cancer 103 | 2,499
ovarian cancer 95 | 8,520
psoriasis 91 | 6,694
glioblastoma 87 | 5,792
osteosarcoma 77 | 7,950
lung cancer 76 | 4,740
lung carcinoma 64 | 2,843
medulloblastoma, large-cell 62 | 6,241
atypical teratoid / rhabdoid tumor 61 | 5,112
malignant mesothelioma 58 | 3,232
invasive ductal carcinoma 57 | 2,951
lung adenocarcinoma 57 | 2,716
adult high grade glioma 55 | 3,801
ependymoma 55 | 4,679
interstitial cystitis 54 | 2,312
non-small cell lung cancer 48 | 2,890
Astrocytoma, Pilocytic 47 | 3,081
Breast cancer 47 | 3,578
tuberculosis 45 | 2,010
ulcerative colitis 44 | 1,819
diabetes mellitus 42 | 1,728
cystic fibrosis 40 | 1,696
Schizophrenia 38 | 1,160
astrocytic glioma 38 | 2,597
group 3 medulloblastoma 38 | 4,104
oligodendroglioma 36 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
Rheumatoid arthritis 32 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
subependymal giant cell astrocytoma 31 | 2,287
Breast Neoplasms 30 | 445
Mammary Neoplasms 30 | 425
Obesity 30 | 678
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
Atherosclerosis 29 | 291
adrenocortical carcinoma 29 | 1,428
ductal carcinoma in situ 29 | 1,745
pancreatic cancer 29 | 2,398
Kidney cancer 28 | 2,613
Asthma 27 | 385
pituitary cancer 27 | 1,972
Bipolar Disorder 26 | 666
Arthritis 25 | 290
Depressive disorder 25 | 409
colon cancer 25 | 1,478
cutaneous lupus erythematosus 25 | 1,057
Hypertension 24 | 396
Liver Cirrhosis, Experimental 24 | 769
primitive neuroectodermal tumor 24 | 3,035
Heart disease 23 | 306
breast carcinoma 23 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
Coronary artery disease 22 | 268
Kidney disease 22 | 430
Vascular disease 22 | 319
group 4 medulloblastoma 22 | 1,855
astrocytoma 21 | 1,146
Hypertensive disease 20 | 292
Alzheimer's disease 19 | 658
Atopic dermatitis 19 | 952
Cerebrovascular disease 19 | 238
Lung disease 19 | 142
Autosomal recessive predisposition 18 | 1,442
Inflammation 18 | 120
Lung Neoplasms 18 | 232
Melanoma 18 | 711
Multiple myeloma 18 | 1,332
primary pancreatic ductal adenocarcinoma 18 | 1,109
Carcinoma, Hepatocellular 17 | 228
Hypersensitivity reaction type II disease 17 | 253
Liver carcinoma 17 | 240
Pneumonia 17 | 174
Prostatic Neoplasms 17 | 495
Pulmonary Fibrosis 17 | 106
juvenile dermatomyositis 17 | 1,187
Cleft Palate 16 | 271
Endometriosis 16 | 540
Multiple Sclerosis 16 | 540
Myocardial Ischemia 16 | 169
Parkinson's disease 16 | 392
Short stature 16 | 531
Stomach Neoplasms 16 | 300
aldosterone-producing adenoma 16 | 665
nasopharyngeal carcinoma 16 | 1,058
Hypersensitivity 15 | 63
Liver Cirrhosis 15 | 181
Mental Depression 15 | 333
Seizures 15 | 596
Skin cancer 15 | 469
spina bifida 15 | 1,074
Dermatitis 14 | 157
Downward slant of palpebral fissure 14 | 158
Epilepsy 14 | 792
Hypereosinophilic syndrome 14 | 71
Major Depressive Disorder 14 | 301
Neoplasm Invasiveness 14 | 161
Orbital separation excessive 14 | 244
Osteoporosis 14 | 363
gastric carcinoma 14 | 807

Tissue

Endocrine System 190 | 18,159
Liver and Pancreas 189 | 16,750
Digestive Tract 187 | 17,369
Female tissues 187 | 17,400
Male tissues 184 | 17,142
Skin and soft tissues 184 | 17,230
Blood and immune system 183 | 16,909
Respiratory system 183 | 16,393
Urinary Tract 182 | 16,678
Nervous System 177 | 16,725
Cardiovascular System 168 | 15,192

Target Family

Non-IDG 116 | 12,091
Kinase 26 | 634
GPCR 24 | 408
Enzyme 21 | 4,145
Transcription Factor 3 | 1,400
Ion Channel 2 | 344
Transporter 2 | 473

GO Process

positive regulation of ERK1 an... 194 | 194
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Nephronectin NPNT Tbio Non-IDG -1.54450 37.2 104
ALK and LTK ligand 1 ALKAL1 Tbio Non-IDG -0.60942 2.72 20
Platelet-derived growth factor C PDGFC Tbio Non-IDG -2.03910 120.6 226
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336
C-C motif chemokine 19 CCL19 Tbio Non-IDG -2.45693 253.7 310
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.91187 99.0 476