Development Level

Tchem 6 | 1,598
Tbio 4 | 11,445
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal seminal vesicle morph... 1 | 114
decreased bone mineral content 1 | 151
decreased erythrocyte cell num... 1 | 62
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56

Disease

Cancer 10 | 2,499
Carcinoma 10 | 11,493
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
invasive ductal carcinoma 6 | 2,951
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Liver Cirrhosis, Experimental 5 | 769
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
primitive neuroectodermal tumor 5 | 3,035
Kidney disease 4 | 430
Vascular disease 4 | 319
adult high grade glioma 4 | 3,801
cystic fibrosis 4 | 1,696
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
oligodendroglioma 4 | 2,850
Carcinoma, Hepatocellular 3 | 228
Chronic Lymphocytic Leukemia 3 | 262
Colonic Neoplasms 3 | 142
Depressive disorder 3 | 409
Epilepsy 3 | 792
Liver carcinoma 3 | 240
Multiple myeloma 3 | 1,332
Psychotic Disorders 3 | 151
Pulmonary Fibrosis 3 | 106
Renal Cell Carcinoma 3 | 214
Seizures 3 | 596
Skin Neoplasms 3 | 69
Small head 3 | 374
astrocytoma 3 | 1,146
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Adult onset 2 | 82
Anxiety 2 | 136
Anxiety disease 2 | 113
Atherosclerosis 2 | 291
Athetosis 2 | 16
Atopic dermatitis 2 | 952
Bladder Neoplasm 2 | 112
Bradykinesia 2 | 34
Calcinosis 2 | 70
Carcinoma, Squamous Cell 2 | 110
Chorea 2 | 29
Choreatic disease 2 | 52
Clouding of corneal stroma 2 | 50
Common variable immunodeficiency 2 | 101
Corneal Opacity 2 | 53
Decreased platelet count 2 | 111
Dilated ventricles (finding) 2 | 121
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Forgetful 2 | 40
Heart disease 2 | 306
Hepatomegaly 2 | 285
Hyperreflexia 2 | 209
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Liver neoplasms 2 | 130
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
Malformations of Cortical Development, Group II 2 | 31
Memory Loss 2 | 40
Memory impairment 2 | 40
Mental deterioration 2 | 32
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neuroblastoma 2 | 80
Parkinsonian Disorders 2 | 56
Progressive disorder 2 | 142
Skin cancer 2 | 469
Squamous cell carcinoma 2 | 129
Status Epilepticus 2 | 98
Stomach Neoplasms 2 | 300
Thin upper lip vermilion 2 | 67
Thrombocytopenia 2 | 197
Tremor 2 | 113
Urinary Bladder Neoplasms 2 | 114
Urinary Incontinence 2 | 50
Urinary bladder cancer 2 | 36
adrenocortical carcinoma 2 | 1,428
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Kinase 6 | 634
Enzyme 3 | 4,145
Non-IDG 3 | 12,091
Transcription Factor 1 | 1,400

GO Process

positive regulation of DNA bio... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spliceosome RNA helicase DDX39B DDX39B Tbio Enzyme -1.74494 60.6 182
Serine/threonine-protein kinase D2 PRKD2 Tchem Kinase -1.46203 23.4 417
Fibroblast growth factor receptor 4 FGFR4 Tclin Kinase -2.44255 276.4 502
Serine/threonine-protein kinase PAK 3 PAK3 Tchem Kinase -1.35059 21.1 377
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705
Hepatocyte growth factor HGF Tchem Enzyme -3.30841 2392.1 724
Regulator of cell cycle RGCC RGCC Tbio Non-IDG -2.32382 150.8 54
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.27151 1795.5 434
Beta-arrestin-2 ARRB2 Tbio Non-IDG -2.72576 487.8 250