Development Level

Tbio 26 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 2 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
cleft palate 1 | 8
cyanosis 1 | 7
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hydrometra 1 | 53
hyperactivity 1 | 148
increased body length 1 | 32
increased grip strength 1 | 41
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 22 | 11,493
ovarian cancer 22 | 8,520
osteosarcoma 16 | 7,950
psoriasis 16 | 6,694
ependymoma 14 | 4,679
lung cancer 14 | 4,740
malignant mesothelioma 13 | 3,232
Cancer 12 | 2,499
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
pancreatic cancer 11 | 2,398
Breast cancer 10 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung adenocarcinoma 10 | 2,716
invasive ductal carcinoma 9 | 2,951
cystic fibrosis 8 | 1,696
group 4 medulloblastoma 8 | 1,855
interstitial cystitis 8 | 2,312
Brachydactyly 7 | 156
Epilepsy 7 | 792
Kidney cancer 7 | 2,613
Rheumatoid arthritis 7 | 1,191
gastric carcinoma 7 | 807
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Cryptorchidism 6 | 296
Hypertension 6 | 396
Seizures 6 | 596
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
primary pancreatic ductal adenocarcinoma 6 | 1,109
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Astrocytoma, Pilocytic 5 | 3,081
Cognitive delay 5 | 608
Craniofacial Abnormalities 5 | 151
Global developmental delay 5 | 608
Hemangioma, Cavernous 5 | 20
Hereditary hemorrhagic telangiectasia 5 | 13
Mental and motor retardation 5 | 608
Osteoarthritis 5 | 184
Short stature 5 | 531
Telangiectasis 5 | 36
acute quadriplegic myopathy 5 | 1,158
pituitary cancer 5 | 1,972
Arthritis, Rheumatoid 4 | 174
Atopic dermatitis 4 | 952
Bilateral fifth finger clinodactyly 4 | 110
Breast Neoplasms 4 | 445
Cholecystitis 4 | 18
Cleft Palate 4 | 271
Curvature of little finger 4 | 110
Dull intelligence 4 | 645
Epistaxis 4 | 43
Failure to gain weight 4 | 365
Fetal Growth Retardation 4 | 189
Hypertension, Portal 4 | 22
Infant, Small for Gestational Age 4 | 176
Intellectual disability 4 | 1,016
Intermittent migraine headaches 4 | 68
Intrauterine retardation 4 | 176
Iron-Refractory Iron Deficiency Anemia 4 | 15
Liver Cirrhosis 4 | 181
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Migraine Disorders 4 | 76
Muscle hypotonia 4 | 571
Pediatric failure to thrive 4 | 365
Polydactyly 4 | 107
Poor school performance 4 | 645
Short distal phalanges 4 | 50
Small head 4 | 374
Sparse hair 4 | 59
Spontaneous haematoma 4 | 8
Strabismus 4 | 270
Telangiectasia of the skin 4 | 39
Tetralogy of Fallot 4 | 63
Thin, sparse hair 4 | 59
Visceral angiomatosis 4 | 13
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Congenital Epicanthus 3 | 177
Curvature of spine 3 | 282
Small nose 3 | 132
Ventricular Septal Defects 3 | 119
colon cancer 3 | 1,478
nasopharyngeal carcinoma 3 | 1,058

Tissue

Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Digestive Tract 31 | 17,369
Blood and immune system 30 | 16,909
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Cardiovascular System 29 | 15,192
Urinary Tract 29 | 16,678

Target Family

Non-IDG 16 | 12,091
Transcription Factor 11 | 1,400
Kinase 3 | 634
Enzyme 2 | 4,145

GO Process

positive regulation of BMP sig... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Protein pelota homolog PELO Tbio Non-IDG -1.33842 18.2 100
E3 ubiquitin-protein ligase RNF165 RNF165 Tdark Non-IDG 0.33 0.39 113
Twisted gastrulation protein homolog 1 TWSG1 Tbio Non-IDG -2.47209 291.9 79