Development Level

Tdark 29 | 6,588
Tbio 16 | 11,445
Tclin 4 | 613

Disease

osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
interstitial cystitis 9 | 2,312
lung cancer 9 | 4,740
ulcerative colitis 9 | 1,819
periodontitis 8 | 293
Multiple myeloma 7 | 1,332
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
chronic lymphosyte leukemia 6 | 204
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
tuberculosis 6 | 2,010
Amebiasis 5 | 21
Arthritis 5 | 290
colon cancer 5 | 1,478
pancreatic cancer 5 | 2,398
Asthma 4 | 385
Crohn Disease 4 | 45
Isolated growth hormone deficiency 4 | 30
Leukemia 4 | 104
Lymphoma 4 | 81
Allergic hypersensitivity disease 3 | 126
Autosomal recessive predisposition 3 | 1,442
Carcinoma 3 | 11,493
Chronic Lymphocytic Leukemia 3 | 262
Diarrhea 3 | 253
Exanthema 3 | 43
Fever 3 | 138
Meningitis 3 | 67
Multiple Sclerosis 3 | 540
Myositis 3 | 30
Osteomyelitis 3 | 42
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
posterior fossa group A ependymoma 3 | 468
sarcoidosis 3 | 370
AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE 2 | 8
Agammaglobulinemia 2 | 34
Agammaglobulinemia, non-Bruton type 2 | 8
Allergic rhinitis 2 | 94
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Brain Injuries 2 | 65
Cancer 2 | 2,499
Chronic otitis media 2 | 52
Conjunctivitis 2 | 53
Conjunctivitis, recurrent 2 | 37
Coughing 2 | 25
Dermatitis 2 | 157
Exanthem 2 | 37
Failure to gain weight 2 | 365
Fatigue 2 | 182
Glomerulonephritis 2 | 46
Hepatitis B 2 | 108
Immunologic Deficiency Syndromes 2 | 113
Increased susceptibility to bacterial infections 2 | 42
Infantile onset 2 | 238
Infection of bone 2 | 19
Infectious disease of lung 2 | 29
Inflammation 2 | 120
Inflammatory Bowel Disease (Crohn Disease) 1 2 | 3
Inflammatory Bowel Diseases 2 | 35
Inflammatory bowel disease 2 | 151
Influenza 2 | 142
Kappa-Chain Deficiency 2 | 2
Leishmaniasis 2 | 47
Leukemia, Lymphocytic, Chronic, B-Cell 2 | 34
Liver disease 2 | 237
Lupus Erythematosus, Systemic 2 | 67
Malaria 2 | 160
Multiple pulmonary infections 2 | 29
Myocardial Infarction 2 | 151
Paranasal Sinus Diseases 2 | 34
Pediatric failure to thrive 2 | 365
Pneumonia 2 | 174
Polycystic ovary syndrome 2 | 360
Prone to bacterial infection 2 | 42
Recurrent bacterial infection 2 | 42
Recurrent pneumonia 2 | 29
Recurrent pulmonary infections 2 | 29
Recurrent respiratory infections 2 | 141
Recurrent skin infections 2 | 21
Rheumatoid arthritis 2 | 1,191
Sinusitis 2 | 65
Systemic lupus erythematosus 2 | 194
Uveitis 2 | 103
Vascular disease 2 | 319
adult high grade glioma 2 | 3,801
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis and chronic rhinosinusitis 2 | 214
ear infection chronic 2 | 52
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
primary Sjogren syndrome 2 | 735
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Male tissues 7 | 17,142
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Liver and Pancreas 6 | 16,750
Nervous System 6 | 16,725
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 49 | 12,091

GO Process

positive regulation of B cell ... 49 | 49
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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