Development Level

Tbio 10 | 11,445
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal maxilla morphology 1 | 17
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
medulloblastoma, large-cell 9 | 6,241
lung cancer 8 | 4,740
Breast cancer 7 | 3,578
Cancer 7 | 2,499
malignant mesothelioma 7 | 3,232
group 3 medulloblastoma 6 | 4,104
juvenile dermatomyositis 6 | 1,187
Waldenstrons macroglobulinemia 5 | 765
atypical teratoid / rhabdoid tumor 5 | 5,112
pancreatic cancer 5 | 2,398
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Long eyelashes 4 | 37
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Poor school performance 4 | 645
Short stature 4 | 531
Strabismus 4 | 270
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
glioblastoma 4 | 5,792
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
primitive neuroectodermal tumor 4 | 3,035
Acquired scoliosis 3 | 281
Breast Neoplasms 3 | 445
Broad flat nasal bridge 3 | 236
Bushy eyebrows 3 | 49
Congenital deafness 3 | 185
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Deafness 3 | 198
Dental abnormalities 3 | 60
Epilepsy 3 | 792
Feeding difficulties in infancy 3 | 175
Fetal Growth Retardation 3 | 189
Hearing Loss, Partial 3 | 185
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Kidney cancer 3 | 2,613
Muscle hypotonia 3 | 571
Nasal bridge wide 3 | 236
Nystagmus 3 | 317
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
Seizures 3 | 596
Small head 3 | 374
Tooth Abnormalities 3 | 69
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
hearing impairment 3 | 199
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abnormality of cardiovascular system morphology 2 | 23
Asthma 2 | 385
Cerebellar hypoplasia and atrophy 2 | 41
Coarse facial features 2 | 108
Coffin-Siris syndrome 2 | 17
Colonic Neoplasms 2 | 142
Concave bridge of nose 2 | 195
Crohn's disease 2 | 321
Depressed nasal bridge 2 | 195
Depressed nasal ridge 2 | 51
Depressed nasal root/bridge 2 | 195
Hypoplastic mandible condyle 2 | 275
Immune system cancer 2 | 140
Joint hyperflexibility 2 | 78
Large intestine cancer 2 | 126
Lens Opacities 2 | 231
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Parkinson's disease 2 | 392
Prostate cancer 2 | 175
Recurrent respiratory infections 2 | 141
Rheumatoid arthritis 2 | 1,191
Stomach Neoplasms 2 | 300
Thickened facial skin with coarse facial features 2 | 108
adult high grade glioma 2 | 3,801
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
nephrosclerosis 2 | 333
pancreatic carcinoma 2 | 562
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 5 | 12,091
Transcription Factor 5 | 1,400
Enzyme 3 | 4,145
Epigenetic 3 | 242

GO Process

positive regulation by host of... 16 | 16
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 639 ZNF639 Tbio Transcription Factor -0.60566 5.21 49
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
Serine protease hepsin HPN Tchem Enzyme -2.50023 316.0 125
Transcription initiation factor TFIID subunit 11 TAF11 Tbio Non-IDG -0.83855 7.10 194
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 NUCKS1 Tbio Enzyme -1.43623 29.2 148
Chromodomain-helicase-DNA-binding protein 1 CHD1 Tbio Epigenetic -2.14472 148.3 122
Ribosomal RNA processing protein 1 homolog B RRP1B Tbio Non-IDG -0.93988 10.3 81
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SMARCB1 Tbio Non-IDG -2.77635 619.8 379
SNW domain-containing protein 1 SNW1 Tbio Non-IDG -1.59688 46.1 88
Transcription factor AP-4 TFAP4 Tbio Transcription Factor -1.33384 19.4 276