Development Level

Tbio 3 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased body length 2 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
increased blood urea nitrogen ... 1 | 48
male infertility 1 | 123
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 5 | 8,520
lung cancer 4 | 4,740
psoriasis 4 | 6,694
Secondary progressive multiple sclerosis 3 | 10
Sleeping sickness 3 | 37
invasive ductal carcinoma 3 | 2,951
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Leishmaniasis 2 | 47
Multiple myeloma 2 | 1,332
atypical teratoid / rhabdoid tumor 2 | 5,112
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ulcerative colitis 2 | 1,819
Adenocarcinoma of lung 1 | 142
Arthritis, Rheumatoid 1 | 174
Auricular malformation 1 | 41
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Barrett's esophagus 1 | 182
Bipolar Disorder 1 | 666
Bipolar II disorder 1 | 1
Broad-based gait 1 | 19
Carcinoma of colon 1 | 32
Class III malocclusion 1 | 78
Cleft uvula 1 | 27
Colonic Neoplasms 1 | 142
Colorectal Neoplasms 1 | 243
Congenital clubfoot 1 | 109
Congenital pectus carinatum 1 | 52
Coronary artery disease 1 | 268
Decreased muscle mass 1 | 28
Disease Models, Animal 1 | 155
Dysarthria 1 | 192
Epilepsy 1 | 792
Facial asymmetry 1 | 32
Frequent fractures 1 | 53
Full lower lip 1 | 64
HIV Infections 1 | 102
High, narrow palate 1 | 32
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Hyperextensible digits 1 | 7
Hypernasal voice 1 | 39
Hypertrophy of lower jaw 1 | 78
Inadequate arch length for tooth size 1 | 45
Increased fracture rate 1 | 53
Increased size of mandible 1 | 78
Intestinal benign neoplasm 1 | 12
Kidney hypertrophy 1 | 4
Kyphoscoliosis deformity of spine 1 | 60
Long fingers 1 | 9
Long hallux 1 | 5
MENTAL RETARDATION, X-LINKED, SNYDER-ROBINSON TYPE 1 | 1
Mandibular hyperplasia 1 | 78
Mood Disorders 1 | 184
Narrow hands 1 | 6
Nasal voice 1 | 39
Oral squamous cell carcinoma 1 | 11
Osteoporosis 1 | 363
Papilloma 1 | 44
Pectus excavatum 1 | 100
Phenotypic variability 1 | 150
Priapism 1 | 5
Primary ciliary dyskinesia 1 | 76
Prominent lower lip 1 | 64
Seizures 1 | 596
Severe myopia 1 | 22
Short philtrum 1 | 53
Simple ear 1 | 41
Skin Neoplasms 1 | 69
Syndromic X-linked intellectual disability Snyder type 1 | 21
Tall stature 1 | 34
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Varying degree of multiple fractures 1 | 53
Vascular disease 1 | 319
Waldenstrons macroglobulinemia 1 | 765
Wide spaced nipples 1 | 46
X- linked recessive 1 | 110
acute quadriplegic myopathy 1 | 1,158
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
lung adenocarcinoma 1 | 2,716
mandibular excess (physical finding) 1 | 78
oligodendroglioma 1 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
spina bifida 1 | 1,074

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 7 | 4,145

GO Process

polyamine metabolic process 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
S-adenosylmethionine decarboxylase proenzyme AMD1 Tchem Enzyme -3.21826 1586.8 141
Spermine synthase SMS Tchem Enzyme -1.50353 28.6 215
Spermidine synthase SRM Tchem Enzyme -1.65951 38.0 172
Ornithine decarboxylase antizyme 3 OAZ3 Tbio Enzyme -1.26993 18.3 58
Ornithine decarboxylase antizyme 1 OAZ1 Tbio Enzyme -1.36094 22.0 69
Ornithine decarboxylase ODC1 Tclin Enzyme -3.37636 2514.9 440
Ornithine decarboxylase antizyme 2 OAZ2 Tbio Enzyme -0.57513 2.88 73