Development Level

Tbio 14 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal locomotor behavior 1 | 24
decreased bone mineral density 1 | 126
impaired glucose tolerance 1 | 75
increased circulating thyroxin... 1 | 7
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
thrombocytopenia 1 | 56

Disease

Carcinoma 14 | 11,493
osteosarcoma 12 | 7,950
Cancer 9 | 2,499
ovarian cancer 9 | 8,520
lung cancer 7 | 4,740
psoriasis 7 | 6,694
Kidney cancer 6 | 2,613
Thrombocytopenia 6 | 197
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
Alzheimer's disease 4 | 658
Breast cancer 4 | 3,578
Decreased platelet count 4 | 111
Muscle hypotonia 4 | 571
Parkinson's disease 4 | 392
Schizophrenia 4 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
pancreatic carcinoma 4 | 562
Bleeding time prolonged 3 | 31
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Conduction disorder of the heart 3 | 79
Congenital Epicanthus 3 | 177
Cryptorchidism 3 | 296
EKG abnormalities 3 | 78
Ecchymosis 3 | 66
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Epistaxis 3 | 43
Immune system cancer 3 | 140
Increased tendency to bruise 3 | 66
Intellectual disability 3 | 1,016
Isolated cases 3 | 72
Low set ears 3 | 181
Myocardial Infarction 3 | 151
Short stature 3 | 531
Vascular disease 3 | 319
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Anemia 2 | 365
Autistic Disorder 2 | 364
Blepharoptosis 2 | 231
Brain Ischemia 2 | 110
Breast Neoplasms 2 | 445
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cerebrovascular disease 2 | 238
Congenital heart disease 2 | 93
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Delayed speech and language development 2 | 112
Dementia 2 | 175
Downward slant of palpebral fissure 2 | 158
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Exophthalmos 2 | 112
Heart disease 2 | 306
High forehead 2 | 102
Highly variable severity 2 | 157
Kidney disease 2 | 430
Language Delay 2 | 112
Leukemia 2 | 104
MYH-9 related disease 2 | 12
Nasal bridge wide 2 | 236
Nervous System Diseases 2 | 53
Nonsyndromic deafness 2 | 142
Osteoporosis 2 | 363
Pectus excavatum 2 | 100
Penile hypospadias 2 | 106
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Retinal Detachment 2 | 51
Seizures 2 | 596
Speech Delay 2 | 112
Speech impairment 2 | 112
Status Epilepticus 2 | 98
Strabismus 2 | 270
Tall forehead 2 | 102
Toxic encephalopathy 2 | 141
Upward slant of palpebral fissure 2 | 75
Variable expressivity 2 | 157
Ventricular Septal Defects 2 | 119
breast carcinoma 2 | 1,638
nervous system disorder 2 | 53

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Cardiovascular System 18 | 15,192
Male tissues 18 | 17,142
Urinary Tract 18 | 16,678
Nervous System 17 | 16,725

Target Family

Non-IDG 9 | 12,091
Transcription Factor 5 | 1,400
Enzyme 4 | 4,145
Epigenetic 1 | 242

GO Process

platelet formation 19 | 19
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Myosin-9 MYH9 Tbio Non-IDG -3.01272 1033.4 349
Erythroid transcription factor GATA1 Tbio Transcription Factor -3.00341 967.9 708
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Zinc finger protein ZFPM1 ZFPM1 Tbio Transcription Factor -2.52665 326.6 82
Neurobeachin-like protein 2 NBEAL2 Tbio Non-IDG -2.41750 251.4 18
T-cell acute lymphocytic leukemia protein 1 TAL1 Tbio Transcription Factor -2.40917 258.8 466