Development Level

Tbio 28 | 11,651
Tchem 9 | 1,388
Tclin 4 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 3 | 187
increased heart weight 3 | 62
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
enlarged heart 2 | 210
hyperactivity 2 | 148
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal optic disc morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
shortened RR interval 1 | 17

Disease

Carcinoma 32 | 11,493
ovarian cancer 25 | 8,520
osteosarcoma 23 | 7,950
Cancer 21 | 2,499
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
pancreatic cancer 18 | 2,398
medulloblastoma, large-cell 15 | 6,241
non-small cell lung cancer 15 | 2,890
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
psoriasis 13 | 6,694
Kidney cancer 12 | 2,613
invasive ductal carcinoma 12 | 2,951
lung carcinoma 12 | 2,843
subependymal giant cell astrocytoma 12 | 2,287
Astrocytoma, Pilocytic 11 | 3,081
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
tuberculosis 11 | 2,010
colon cancer 10 | 1,478
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Osteoporosis 9 | 363
adult high grade glioma 9 | 3,801
cystic fibrosis 9 | 1,696
Autosomal recessive predisposition 8 | 1,442
Epistaxis 8 | 43
Liver Cirrhosis, Experimental 8 | 769
Schizophrenia 8 | 1,160
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Gastrointestinal Hemorrhage 7 | 52
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
interstitial cystitis 7 | 2,312
malignant mesothelioma 7 | 3,232
pituitary cancer 7 | 1,972
Bleeding tendency 6 | 37
Ecchymosis 6 | 66
Gingival Hemorrhage 6 | 18
Increased tendency to bruise 6 | 66
Intellectual disability 6 | 1,016
Kidney disease 6 | 430
Thrombocytopenia 6 | 197
breast carcinoma 6 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Acute coronary syndrome 5 | 39
Anemia 5 | 365
Bleeding time prolonged 5 | 31
Cerebrovascular disease 5 | 238
Coronary artery disease 5 | 268
Epilepsy 5 | 792
Hypothyroidism 5 | 122
Rheumatoid arthritis 5 | 1,191
Splenomegaly 5 | 190
Thrombosis 5 | 46
Vascular disease 5 | 319
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
pancreatic carcinoma 5 | 562
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Atherosclerosis 4 | 291
Autoimmune thrombocytopenic purpura 4 | 13
Beckwith-Wiedemann syndrome 4 | 44
Bernard-Soulier syndrome 4 | 14
Brachydactyly 4 | 156
Cleft Palate 4 | 271
Decreased platelet count 4 | 111
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Glanzmann's thrombasthenia 4 | 23
Hemoglobin low 4 | 124
Hypertensive disease 4 | 292
Hypoparathyroidism 4 | 41
Intermenstrual heavy bleeding 4 | 4
Low intelligence 4 | 645
Menorrhagia 4 | 25
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Obesity 4 | 678
Petechiae 4 | 13
Poor school performance 4 | 645
Short stature 4 | 531
Stomach cancer 4 | 30
Thrombophilia 4 | 38
Venous Thrombosis 4 | 47
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Cushing's syndrome 3 | 48
Status Epilepticus 3 | 98
Stomach Neoplasms 3 | 300

Tissue

Digestive Tract 40 | 17,369
Female tissues 40 | 17,400
Male tissues 40 | 17,142
Respiratory system 40 | 16,393
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Endocrine System 39 | 18,159
Liver and Pancreas 39 | 16,750
Urinary Tract 39 | 16,678
Cardiovascular System 37 | 15,192
Nervous System 37 | 16,725

Target Family

Non-IDG 30 | 12,091
Kinase 5 | 634
Enzyme 3 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

platelet aggregation 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Talin-1 TLN1 Tbio Non-IDG -1.94109 90.0 426
Fermitin family homolog 3 FERMT3 Tbio Non-IDG -1.84107 75.9 169
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS Tbio Non-IDG -2.63356 1389.7 509
Acidic fibroblast growth factor intracellular-binding protein FIBP Tbio Non-IDG -0.62020 5.07 130
Integrin-linked protein kinase ILK Tchem Kinase -2.75450 679.1 608
Tetraspanin-32 TSPAN32 Tbio Non-IDG -0.97140 8.31 153
Erythroid transcription factor GATA1 Tbio Transcription Factor -3.00341 967.9 708
Fibrinogen beta chain FGB Tbio Non-IDG -2.09043 116.8 352
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351