Development Level

Tbio 18 | 10,625
Tchem 8 | 1,890
Tclin 1 | 602

IMPC Phenotype

preweaning lethality, complete... 4 | 633
decreased grip strength 2 | 123
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal facial morphology 1 | 9
abnormal ovary morphology 1 | 3
absent epididymis 1 | 2
cleft palate 1 | 6
corneal opacity 1 | 25
cyanosis 1 | 6
decreased bone mineral density 1 | 126
decreased kidney weight 1 | 7
decreased spleen weight 1 | 13
impaired pupillary reflex 1 | 14
increased circulating HDL chol... 1 | 63
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
narrow eye opening 1 | 15
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11

Disease

Cancer 15 | 2,346
medulloblastoma, large-cell 15 | 6,234
psoriasis 15 | 6,685
lung cancer 13 | 4,473
ovarian cancer 13 | 8,491
osteosarcoma 12 | 7,933
atypical teratoid / rhabdoid tumor 11 | 4,369
pituitary cancer 11 | 1,972
glioblastoma 9 | 5,572
lung carcinoma 9 | 2,844
malignant mesothelioma 9 | 3,163
pilocytic astrocytoma 9 | 3,086
primitive neuroectodermal tumor 9 | 3,031
invasive ductal carcinoma 8 | 2,950
non-small cell lung cancer 8 | 2,798
Holoprosencephaly 7 | 52
adult high grade glioma 7 | 2,148
oligodendroglioma 7 | 2,849
ependymoma 6 | 2,514
group 4 medulloblastoma 6 | 1,875
interstitial cystitis 6 | 2,299
pediatric high grade glioma 6 | 2,712
Adenoma 5 | 165
Hypopituitarism 5 | 36
Microphthalmia 5 | 79
Polydactyly 5 | 93
ductal carcinoma in situ 5 | 1,745
lung adenocarcinoma 5 | 2,714
posterior fossa group A ependymoma 5 | 1,511
Carcinoma 4 | 2,147
Cleft Lip 4 | 91
Cleft palate 4 | 125
Craniofacial Abnormalities 4 | 147
Panhypopituitarism 4 | 11
Prostatic Neoplasms 4 | 471
atypical teratoid/rhabdoid tumor 4 | 1,095
cystic fibrosis 4 | 1,670
group 3 medulloblastoma 4 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
pancreatic cancer 4 | 2,300
sonic hedgehog group medulloblastoma 4 | 1,482
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 644
Bladder Neoplasm 3 | 109
Breast cancer 3 | 3,098
Congenital diaphragmatic hernia 3 | 44
Endometriosis 3 | 535
Esophageal atresia 3 | 25
Fibrodysplasia ossificans progressiva 3 | 17
Intellectual disability 3 | 573
Mammary Neoplasms 3 | 410
Neoplasm Invasiveness 3 | 127
Parkinson's disease 3 | 364
Pituitary hypoplasia 3 | 15
Prostate cancer 3 | 172
Rheumatoid Arthritis 3 | 1,170
Stomach Neoplasms 3 | 282
Synostosis 3 | 18
active ulcerative colitis 3 | 477
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
colon cancer 3 | 1,475
diabetes mellitus 3 | 1,663
esophageal adenocarcinoma 3 | 737
ulcerative colitis 3 | 2,087
Alobar Holoprosencephaly 2 | 14
Atopic dermatitis 2 | 944
Autistic Disorder 2 | 320
Colorectal Neoplasms 2 | 217
Degenerative polyarthritis 2 | 93
Disease Progression 2 | 125
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Epilepsy 2 | 346
Hydrocephalus 2 | 60
Hypothyroidism 2 | 89
Lobar Holoprosencephaly 2 | 14
Lung disease 2 | 136
Myopia 2 | 99
Neoplastic Syndromes, Hereditary 2 | 48
Nevoid basal cell carcinoma syndrome 2 | 9
Osteoporosis 2 | 259
Peripheral Neuropathy 2 | 303
Pick disease 2 | 1,893
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 2 | 14
Schizophrenia 2 | 503
Semilobar Holoprosencephaly 2 | 14
Squamous cell carcinoma 2 | 96
Squamous cell carcinoma of esophagus 2 | 82
adrenocortical carcinoma 2 | 1,427
breast carcinoma 2 | 1,614
glioblastoma multiforme 2 | 347
interstitial lung disease 2 | 292
juvenile dermatomyositis 2 | 1,189
medulloblastoma 2 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
tuberculosis 2 | 1,563

Tissue

Blood and immune system 27 | 17,994
Cardiovascular System 27 | 17,957
Digestive Tract 27 | 18,472
Endocrine System 27 | 18,511
Female tissues 27 | 18,646
Liver and Pancreas 27 | 18,135
Male tissues 27 | 17,968
Nervous System 27 | 18,560
Skin and soft tissues 27 | 18,114
Urinary Tract 27 | 18,443
Respiratory system 25 | 17,483

Target Family

Transcription Factor 17 | 1,400
Non-IDG 4 | 11,969
Enzyme 3 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

pituitary gland development 27 | 27
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein SIX3 SIX3 Tbio Transcription Factor -2.83160 648.7 196
Pituitary adenylate cyclase-activating polypeptide ADCYAP1 Tchem Enzyme -3.03655 1222.0 164
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.31946 194.1 500
Zinc finger protein GLI1 GLI1 Tchem Transcription Factor -2.99657 942.8 372
Endothelial transcription factor GATA-2 GATA2 Tbio Transcription Factor -2.66241 429.5 329
Cadherin-1 CDH1 Tbio Non-IDG -3.81358 5832.3 1347
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.64922 425.0 221
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.54628 325.2 174
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.19530 1539.5 438
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.52825 345.1 271