Development Level

Tbio 22 | 11,651
Tchem 4 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
absent epididymis 1 | 3
cataract 1 | 92
cleft palate 1 | 8
corneal opacity 1 | 32
cyanosis 1 | 7
decreased bone mineral density 1 | 126
decreased lean body mass 1 | 135
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 19 | 11,493
psoriasis 16 | 6,694
Cancer 14 | 2,499
medulloblastoma, large-cell 14 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
osteosarcoma 13 | 7,950
ovarian cancer 13 | 8,520
lung cancer 12 | 4,740
pituitary cancer 11 | 1,972
adult high grade glioma 10 | 3,801
ependymoma 10 | 4,679
glioblastoma 10 | 5,792
Astrocytoma, Pilocytic 9 | 3,081
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
primitive neuroectodermal tumor 9 | 3,035
Cryptorchidism 8 | 296
Holoprosencephaly 8 | 56
Short stature 8 | 531
group 3 medulloblastoma 8 | 4,104
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
Cleft Palate 7 | 271
Muscle hypotonia 7 | 571
Pituitary hypoplasia 7 | 23
Septooptic dysplasia 7 | 19
Strabismus 7 | 270
oligodendroglioma 7 | 2,850
Anterior pituitary hypoplasia 6 | 13
Congenital hypoplasia of penis 6 | 176
Epilepsy 6 | 792
Hypogonadotropic hypogonadism 6 | 89
Hypopituitarism 6 | 40
Intellectual disability 6 | 1,016
Polydactyly 6 | 107
Small head 6 | 374
interstitial cystitis 6 | 2,312
Abnormally small eyeball 5 | 97
Adenoma 5 | 167
Agenesis of corpus callosum 5 | 83
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Cleft Lip 5 | 141
Cleft palate with cleft lip 5 | 23
Constipation 5 | 181
Decreased size of eyeball 5 | 97
Dull intelligence 5 | 645
Fatigue 5 | 182
Hypogonadism, Isolated Hypogonadotropic 5 | 71
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Microphthalmos 5 | 100
Panhypopituitarism 5 | 14
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Seizures 5 | 596
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
Alcoholic Intoxication, Chronic 4 | 289
Bipolar Disorder 4 | 666
Brachydactyly 4 | 156
Craniofacial Abnormalities 4 | 151
Depressive disorder 4 | 409
Dyschezia 4 | 135
Failure to gain weight 4 | 365
Hypoplasia of the optic nerve 4 | 17
Hypotension 4 | 82
Hypothyroidism 4 | 122
Infertility 4 | 188
Isolated somatotropin deficiency 4 | 30
Kidney cancer 4 | 2,613
Low Vision 4 | 174
Mental Depression 4 | 333
Microphthalmia 4 | 76
Nystagmus 4 | 317
Pediatric failure to thrive 4 | 365
Penile hypospadias 4 | 106
Schizophrenia 4 | 1,160
Secondary hypothyroidism 4 | 15
Septo-Optic Dysplasia 4 | 11
Small testicle 4 | 75
Umbilical hernia 4 | 93
Uranostaphyloschisis 4 | 167
Visual Impairment 4 | 174
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Endometriosis 3 | 540
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
esophageal adenocarcinoma 3 | 737

Tissue

Endocrine System 27 | 18,159
Digestive Tract 25 | 17,369
Female tissues 25 | 17,400
Nervous System 25 | 16,725
Skin and soft tissues 25 | 17,230
Blood and immune system 24 | 16,909
Liver and Pancreas 24 | 16,750
Male tissues 23 | 17,142
Respiratory system 23 | 16,393
Urinary Tract 22 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Transcription Factor 18 | 1,400
Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

pituitary gland development 27 | 27
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.58228 355.0 196
Transcription factor SOX-2 SOX2 Tbio Transcription Factor -3.20671 1563.0 1171
Zinc finger protein GLI1 GLI1 Tchem Transcription Factor -3.04303 1054.8 450
Endothelial transcription factor GATA-2 GATA2 Tbio Transcription Factor -2.70355 475.5 354
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266
3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 Tclin Enzyme -1.97806 90.7 131
Homeobox expressed in ES cells 1 HESX1 Tbio Transcription Factor -2.24067 180.1 65
Protein C-ets-1 ETS1 Tbio Transcription Factor -2.89500 760.0 463