Development Level

Tbio 32 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

absent startle reflex 3 | 24
increased or absent threshold ... 3 | 101
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
limb grasping 2 | 41
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
stereotypic behavior 1 | 3
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Retinitis Pigmentosa 31 | 226
Carcinoma 29 | 11,493
Autosomal recessive predisposition 19 | 1,442
Intellectual disability 19 | 1,016
Dull intelligence 17 | 645
Electroretinogram abnormal 17 | 95
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
Nystagmus 16 | 317
Obesity 16 | 678
osteosarcoma 16 | 7,950
psoriasis 16 | 6,694
Cataract 15 | 297
Congenital hypoplasia of penis 15 | 176
Fundus dystrophy 15 | 83
Hypogonadism 15 | 173
Lens Opacities 15 | 231
Sensorineural Hearing Loss (disorder) 15 | 284
Abnormality of retinal pigmentation 13 | 111
Blindness 13 | 88
Retinal pigment epithelial abnormality 13 | 111
Atypical scarring of skin 12 | 62
Broad flat nasal bridge 12 | 236
Cone dystrophy 12 | 71
Difficulties with night vision 12 | 87
Keratoconus 12 | 113
Nasal bridge wide 12 | 236
Night Blindness 12 | 101
Optic Atrophy 12 | 242
Photodysphoria 12 | 121
Photophobia 12 | 121
ovarian cancer 12 | 8,520
Abnormality of the retinal vasculature 11 | 59
Anteverted nostril 11 | 191
Blind Vision 11 | 111
Blindness, Legal 11 | 110
Conductive hearing loss 11 | 123
Congenital anomaly of testis 11 | 52
Glaucoma 11 | 239
Hyperinsulinism 11 | 133
Night blindness, progressive 11 | 51
Ophthalmoplegia 11 | 106
Retinal Degeneration 11 | 106
medulloblastoma, large-cell 11 | 6,241
Breast cancer 9 | 3,578
Ciliopathy 9 | 71
Kidney cancer 9 | 2,613
lung carcinoma 9 | 2,843
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Low Vision 8 | 174
Mental and motor retardation 8 | 608
Nonsyndromic deafness 8 | 142
Usher syndrome 8 | 32
Visual Impairment 8 | 174
cone-rod dystrophy 8 | 59
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
Bardet-Biedl syndrome 7 | 51
Cerebellar Ataxia 7 | 304
Hypertensive disease 7 | 292
Increase in blood pressure 7 | 119
Leber congenital amaurosis 7 | 69
Short stature 7 | 531
ependymoma 7 | 4,679
malignant mesothelioma 7 | 3,232
Bardet-Biedl syndrome 1 6 | 22
Fundus with peripheral 'bony spicules' 6 | 12
Melanoma 6 | 711
Polydactyly 6 | 107
Sensorineural hearing loss 6 | 106
Skin cancer 6 | 469
Usher Syndrome, Type 1 6 | 7
glioblastoma 6 | 5,792
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
Abnormal vision 5 | 52
Asthma 5 | 385
Reduced visual acuity 5 | 63
Scotoma 5 | 22
Usher Syndrome, Type I 5 | 6
Visual field constriction 5 | 36
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
Congenital hypoplasia of ovary 4 | 30
Endometrial cancer 4 | 311
Epilepsy 4 | 792
Hirsutism 4 | 47
Hypoplastic ovary 4 | 30
Liver cancer 4 | 604
Multicystic Dysplastic Kidney 4 | 52
Pallor of optic disc 4 | 39
Pick disease 4 | 1,894
Retinal Dystrophies 4 | 33
Strabismus 4 | 270
Ulnar polydactyly of fingers 4 | 47
astrocytic glioma 4 | 2,597
tuberculosis 4 | 2,010

Tissue

Endocrine System 33 | 18,159
Digestive Tract 32 | 17,369
Female tissues 32 | 17,400
Male tissues 32 | 17,142
Urinary Tract 32 | 16,678
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Blood and immune system 30 | 16,909
Respiratory system 30 | 16,393
Liver and Pancreas 29 | 16,750
Cardiovascular System 25 | 15,192

Target Family

Non-IDG 26 | 12,091
GPCR 2 | 408
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

photoreceptor cell maintenance 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Prominin-1 PROM1 Tbio Non-IDG -3.30229 2035.0 351
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.29040 21.3 0
DNA excision repair protein ERCC-6 ERCC6 Tbio Non-IDG -2.31776 361.5 163
Nucleoredoxin-like protein 1 NXNL1 Tbio Non-IDG -1.13331 14.8 107