Development Level

Tchem 15 | 1,598
Tbio 9 | 11,445
Tclin 6 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

increased mean corpuscular hem... 2 | 96
abnormal locomotor activation 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating creatini... 1 | 39
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating LDL chol... 1 | 13
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 134
long tibia 1 | 25
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 24 | 11,493
osteosarcoma 20 | 7,950
Cancer 16 | 2,499
medulloblastoma, large-cell 16 | 6,241
ovarian cancer 16 | 8,520
atypical teratoid / rhabdoid tumor 15 | 5,112
Schizophrenia 14 | 1,160
glioblastoma 14 | 5,792
psoriasis 14 | 6,694
Astrocytoma, Pilocytic 12 | 3,081
Kidney cancer 12 | 2,613
adult high grade glioma 12 | 3,801
lung cancer 11 | 4,740
ependymoma 10 | 4,679
Breast cancer 9 | 3,578
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
Renal Cell Carcinoma 7 | 214
astrocytoma 7 | 1,146
diabetes mellitus 7 | 1,728
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
Alzheimer's disease 6 | 658
Depressive disorder 6 | 409
Intellectual disability 6 | 1,016
Kidney disease 6 | 430
Neurodegenerative disease 6 | 414
Parkinson's disease 6 | 392
Waldenstrons macroglobulinemia 6 | 765
juvenile dermatomyositis 6 | 1,187
malignant mesothelioma 6 | 3,232
subependymal giant cell astrocytoma 6 | 2,287
Carcinoma, Renal Cell 5 | 124
Cerebellar Ataxia 5 | 304
Diffuse large B-cell lymphoma 5 | 39
Epilepsy 5 | 792
Lymphoma, Large B-Cell, Diffuse 5 | 34
Obesity 5 | 678
Ovarian Neoplasms 5 | 102
Pick disease 5 | 1,894
Prostatic Neoplasms 5 | 495
Toxic encephalopathy 5 | 141
Vascular disease 5 | 319
colon cancer 5 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
ulcerative colitis 5 | 1,819
Carcinoma, Squamous Cell 4 | 110
Cardiomegaly 4 | 116
Disease Models, Animal 4 | 155
Dull intelligence 4 | 645
Endometrial cancer 4 | 311
Heart disease 4 | 306
Hypoplastic mandible condyle 4 | 275
Low intelligence 4 | 645
Mandibular hypoplasia 4 | 275
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Micrognathism 4 | 275
Neoplasm Metastasis 4 | 168
Nerve Degeneration 4 | 121
Poor school performance 4 | 645
Seizures 4 | 596
Skin cancer 4 | 469
Squamous cell carcinoma 4 | 129
Stomach Neoplasms 4 | 300
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
follicular lymphoma 4 | 20
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma 4 | 720
ovarian neoplasm 4 | 99
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acquired scoliosis 3 | 281
Anemia 3 | 365
Arthritis 3 | 290
Asthma 3 | 385
Autistic Disorder 3 | 364
Byzanthine arch palate 3 | 194
Carcinoma, Hepatocellular 3 | 228
Curvature of spine 3 | 282
Dementia 3 | 175
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Major Depressive Disorder 3 | 301
Melanoma 3 | 711
Mental Depression 3 | 333
Multiple myeloma 3 | 1,332
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010

Tissue

Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Male tissues 30 | 17,142
Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Liver and Pancreas 29 | 16,750
Nervous System 29 | 16,725
Skin and soft tissues 29 | 17,230
Cardiovascular System 28 | 15,192
Respiratory system 28 | 16,393
Urinary Tract 28 | 16,678

Target Family

Kinase 25 | 634
Non-IDG 2 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

phosphorylation 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
ALK tyrosine kinase receptor ALK Tclin Kinase -3.44312 2942.9 976
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
Phosphoglycerate kinase 1 PGK1 Tchem Kinase -2.79738 602.5 340
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
LIM domain-containing protein 1 LIMD1 Tbio Non-IDG -1.18859 16.4 149
NAD kinase NADK Tbio Kinase -1.49880 29.8 98
Pantothenate kinase 2, mitochondrial PANK2 Tbio Kinase -2.24581 177.7 253
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Sedoheptulokinase SHPK Tbio Kinase -2.20263 157.8 103