Development Level

Tchem 26 | 1,388
Tclin 25 | 612
Tbio 11 | 11,651
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Targets) 6 | 126
RFA-RM-18-021 6 | 328
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased lean body mass 4 | 135
enlarged heart 3 | 210
preweaning lethality, complete... 3 | 979
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased circulating insulin ... 2 | 76
decreased lymphocyte cell numb... 2 | 83
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased total body fat amoun... 2 | 134
small kidney 2 | 16
abnormal bone structure 1 | 187
abnormal colon morphology 1 | 3
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal ileum morphology 1 | 2
abnormal male genitalia morpho... 1 | 3
abnormal ovary morphology 1 | 7
abnormal pancreas morphology 1 | 13
abnormal testis morphology 1 | 43
absent epididymis 1 | 3
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent testes 1 | 6
absent uterus 1 | 1
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased circulating creatini... 1 | 39
decreased heart weight 1 | 27
decreased vertical activity 1 | 208
enlarged uterus 1 | 11
female infertility 1 | 60
fusion of vertebral arches 1 | 7
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
polycystic kidney 1 | 15
polysyndactyly 1 | 2
preweaning lethality, incomple... 1 | 499
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 49 | 11,493
psoriasis 29 | 6,694
osteosarcoma 24 | 7,950
ovarian cancer 22 | 8,520
glioblastoma 21 | 5,792
medulloblastoma, large-cell 20 | 6,241
Obesity 16 | 678
adult high grade glioma 16 | 3,801
ependymoma 15 | 4,679
lung cancer 15 | 4,740
Astrocytoma, Pilocytic 14 | 3,081
atypical teratoid / rhabdoid tumor 14 | 5,112
invasive ductal carcinoma 14 | 2,951
Cancer 13 | 2,499
Depressive disorder 13 | 409
Schizophrenia 13 | 1,160
group 3 medulloblastoma 13 | 4,104
interstitial cystitis 13 | 2,312
lung adenocarcinoma 13 | 2,716
Asthma 12 | 385
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
lung carcinoma 12 | 2,843
ulcerative colitis 12 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
Alcoholic Intoxication, Chronic 10 | 289
Bipolar Disorder 10 | 666
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
subependymal giant cell astrocytoma 10 | 2,287
tuberculosis 10 | 2,010
Breast cancer 9 | 3,578
Kidney cancer 9 | 2,613
Mental Depression 9 | 333
adrenocortical carcinoma 9 | 1,428
colon cancer 9 | 1,478
cutaneous lupus erythematosus 9 | 1,057
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
Allergic rhinitis 8 | 95
astrocytic glioma 8 | 2,597
Autosomal recessive predisposition 7 | 1,442
Hypertension 7 | 396
Substance Withdrawal Syndrome 7 | 55
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Alcoholism 6 | 45
Allergic conjunctivitis 6 | 22
Atherosclerosis 6 | 291
Common cold 6 | 69
Fever 6 | 138
Heart disease 6 | 306
Major Depressive Disorder 6 | 301
Mood Disorders 6 | 184
Nasal congestion 6 | 23
Nasal discharge 6 | 25
Pain agnosia 6 | 104
Sneezing 6 | 12
breast carcinoma 6 | 1,638
group 4 medulloblastoma 6 | 1,855
mucosa-associated lymphoid tissue lymphoma 6 | 484
primary pancreatic ductal adenocarcinoma 6 | 1,109
Alcohol dependence 5 | 107
Atopic dermatitis 5 | 952
Cerebrovascular disease 5 | 238
Cocaine-Related Disorders 5 | 92
Coronary artery disease 5 | 268
Cough 5 | 25
Essential Hypertension 5 | 94
General anesthesia 5 | 53
Headache disorder 5 | 19
Hyperalgesia 5 | 83
Hypotension 5 | 82
Influenza-like symptoms 5 | 16
Local anesthesia 5 | 40
Migraine 5 | 83
Pain 5 | 103
Parkinson's disease 5 | 392
Rhinitis 5 | 55
Seizures 5 | 596
Unipolar Depression 5 | 250
esophageal adenocarcinoma 5 | 737
Acquired metabolic disease 4 | 336
Attention deficit hyperactivity disorder 4 | 278
Constipation 4 | 181
Down syndrome 4 | 499
Epilepsy 4 | 792
Heart failure 4 | 162
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Multiple Sclerosis 4 | 540
Psychotic Disorders 4 | 151
Urticaria 4 | 67
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
pituitary cancer 4 | 1,972
urothelial carcinoma 4 | 318

Tissue

Endocrine System 57 | 18,159
Nervous System 55 | 16,725
Digestive Tract 54 | 17,369
Female tissues 52 | 17,400
Skin and soft tissues 51 | 17,230
Blood and immune system 49 | 16,909
Male tissues 49 | 17,142
Liver and Pancreas 46 | 16,750
Urinary Tract 46 | 16,678
Respiratory system 44 | 16,393
Cardiovascular System 41 | 15,192

Target Family

GPCR 56 | 408
Non-IDG 5 | 12,091
Enzyme 1 | 4,145
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

phospholipase C-activating G-p... 64 | 64
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336
Neuromedin-B receptor NMBR Tchem GPCR -1.69317 44.0 178
Orexin receptor type 2 HCRTR2 Tclin GPCR -1.47750 26.3 249
Orexin HCRT Tbio Non-IDG -3.27696 2001.9 203
Galanin receptor type 2 GALR2 Tchem GPCR -1.90823 70.4 204
Substance-P receptor TACR1 Tclin GPCR -3.10271 1238.0 435
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
N-formyl peptide receptor 2 FPR2 Tchem GPCR -2.49147 330.9 253