Development Level

Tchem 29 | 1,890
Tclin 26 | 602
Tbio 9 | 10,625
Tdark 1 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 8 | 143

IMPC Term

decreased lean body mass 3 | 195
increased total body fat amoun... 3 | 57
abnormal behavior 2 | 226
decreased bone mineral content 2 | 157
decreased circulating insulin ... 2 | 75
hypoactivity 2 | 89
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
small kidney 2 | 10
small superior vagus ganglion 2 | 20
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal colon morphology 1 | 1
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal ileum morphology 1 | 2
abnormal kidney morphology 1 | 30
abnormal ovary morphology 1 | 3
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
absent epididymis 1 | 2
absent ovary 1 | 2
absent seminal vesicle 1 | 2
absent testes 1 | 2
absent uterus 1 | 1
cardiovascular system phenotyp... 1 | 35
decreased CD8-positive, alpha-... 1 | 26
decreased KLRG1-positive T-hel... 1 | 2
decreased NK T cell number 1 | 28
decreased alpha-beta T cell nu... 1 | 12
decreased anxiety-related resp... 1 | 12
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating thyroxin... 1 | 5
decreased circulating triglyce... 1 | 83
decreased dendritic cell numbe... 1 | 3
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
female infertility 1 | 34
fusion of vertebral arches 1 | 7
improved glucose tolerance 1 | 56
increased KLRG1-positive gamma... 1 | 2
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased sacral vertebrae num... 1 | 62
increased thoracic vertebrae n... 1 | 8
male infertility 1 | 62
no abnormal phenotype detected 1 | 3
polysyndactyly 1 | 2
short tail 1 | 4
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small thymus 1 | 11
vertebral transformation 1 | 12

Disease

psoriasis 28 | 6,685
osteosarcoma 23 | 7,933
ovarian cancer 21 | 8,484
glioblastoma 20 | 5,572
medulloblastoma, large-cell 20 | 6,234
Obesity 14 | 616
invasive ductal carcinoma 14 | 2,950
lung cancer 14 | 4,466
pilocytic astrocytoma 14 | 3,086
ulcerative colitis 14 | 2,087
interstitial cystitis 13 | 2,299
lung adenocarcinoma 13 | 2,713
Asthma 12 | 349
Carcinoma 12 | 2,147
atypical teratoid / rhabdoid tumor 12 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
lung carcinoma 11 | 2,844
malignant mesothelioma 11 | 3,162
pediatric high grade glioma 11 | 2,712
Cancer 10 | 2,346
Schizophrenia 10 | 501
oligodendroglioma 10 | 2,849
pancreatic cancer 10 | 2,300
subependymal giant cell astrocytoma 10 | 2,287
adrenocortical carcinoma 9 | 1,427
colon cancer 9 | 1,475
cutaneous lupus erythematosus 9 | 1,056
ependymoma 9 | 2,514
primitive neuroectodermal tumor 9 | 3,031
Allergic rhinitis 8 | 91
Breast cancer 8 | 3,094
Migraine 8 | 79
non-small cell lung cancer 8 | 2,798
Substance Withdrawal Syndrome 7 | 52
ductal carcinoma in situ 7 | 1,745
gastric carcinoma 7 | 832
group 4 medulloblastoma 7 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
medulloblastoma 7 | 1,524
Alcohol dependence 6 | 107
Allergic conjunctivitis 6 | 25
Atherosclerosis 6 | 275
Attention deficit hyperactivity disorder 6 | 156
Cocaine-Related Disorders 6 | 88
Common cold 6 | 63
Fever 6 | 34
Heart disease 6 | 279
Nasal congestion 6 | 24
Nasal discharge 6 | 26
Pain agnosia 6 | 99
Sneezing 6 | 11
Vascular disease 6 | 281
adult high grade glioma 6 | 2,148
astrocytic glioma 6 | 2,241
astrocytoma 6 | 1,493
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
mucosa-associated lymphoid tissue lymphoma 6 | 480
primary pancreatic ductal adenocarcinoma 6 | 1,271
Atopic dermatitis 5 | 944
Cerebrovascular disease 5 | 231
Cough 5 | 21
Down syndrome 5 | 548
Essential Hypertension 5 | 82
General anesthesia 5 | 53
Headache disorder 5 | 20
Hyperalgesia 5 | 71
Hypertension 5 | 287
Hypertensive disease 5 | 193
Hypotension 5 | 53
Influenza-like symptoms 5 | 17
Local anesthesia 5 | 40
Major Depressive Disorder 5 | 106
Pain 5 | 70
Parkinson's disease 5 | 364
Rhinitis 5 | 46
Seizures 5 | 95
esophageal adenocarcinoma 5 | 737
obsessive-compulsive disorder 5 | 34
posterior fossa group A ependymoma 5 | 1,511
Alcoholic Intoxication, Chronic 4 | 41
Alzheimer's disease 4 | 644
Asthma management 4 | 20
Bipolar Disorder 4 | 266
Constipation 4 | 43
Coronary artery disease 4 | 240
Hypertensive disorder 4 | 58
Panic disorder 4 | 55
Substance abuse 4 | 55
Urticaria 4 | 53
Vasomotor rhinitis 4 | 15
acute quadriplegic myopathy 4 | 1,157
anaphylaxis 4 | 11
cystic fibrosis 4 | 1,665
group 3 medulloblastoma 4 | 2,254
pituitary cancer 4 | 1,972
tuberculosis 4 | 1,557
tuberculosis and treatment for 3 months 4 | 327
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 64 | 18,473
Endocrine System 64 | 18,512
Nervous System 64 | 18,561
Female tissues 63 | 18,647
Urinary Tract 62 | 18,444
Skin and soft tissues 61 | 18,115
Cardiovascular System 58 | 17,958
Liver and Pancreas 57 | 18,136
Male tissues 56 | 17,969
Blood and immune system 54 | 17,995
Respiratory system 52 | 17,484

Target Family

GPCR 57 | 406
Non-IDG 5 | 11,971
Enzyme 1 | 4,146
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

GO Process

phospholipase C-activating G-p... 65 | 65
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin B receptor EDNRB Tclin GPCR -3.24561 1672.0 289
Alpha-1B adrenergic receptor ADRA1B Tclin GPCR -2.30072 198.4 327
Anoctamin-1 ANO1 Tclin Ion Channel -2.48376 362.3 422
Probable G-protein coupled receptor 139 GPR139 Tchem GPCR -1.13244 14.2 92
Histamine H1 receptor HRH1 Tclin GPCR -3.01527 1011.4 345
Mu-type opioid receptor OPRM1 Tclin GPCR -3.20440 1609.2 372
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.16676 150.4 223
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144
Estrogen receptor ESR1 Tclin Nuclear Receptor -3.97123 8119.2 2214
Proteinase-activated receptor 4 F2RL3 Tchem GPCR -1.45693 30.5 262