Development Level

Tbio 16 | 11,445
Tchem 10 | 1,598
Tclin 8 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
decreased circulating aspartat... 1 | 34
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
syndactyly 1 | 23

Disease

Carcinoma 29 | 11,493
ovarian cancer 25 | 8,520
Cancer 22 | 2,499
osteosarcoma 21 | 7,950
psoriasis 18 | 6,694
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
glioblastoma 15 | 5,792
invasive ductal carcinoma 15 | 2,951
Breast cancer 14 | 3,578
Kidney cancer 14 | 2,613
Schizophrenia 13 | 1,160
ependymoma 13 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
malignant mesothelioma 13 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
diabetes mellitus 11 | 1,728
ductal carcinoma in situ 11 | 1,745
group 3 medulloblastoma 11 | 4,104
oligodendroglioma 11 | 2,850
Astrocytoma, Pilocytic 10 | 3,081
breast carcinoma 10 | 1,638
pancreatic cancer 10 | 2,398
Alzheimer's disease 9 | 658
Intellectual disability 9 | 1,016
Pick disease 9 | 1,894
adult high grade glioma 9 | 3,801
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Autosomal recessive predisposition 8 | 1,442
cystic fibrosis 8 | 1,696
interstitial cystitis 8 | 2,312
Liver Cirrhosis, Experimental 7 | 769
Seizures 7 | 596
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
Breast Neoplasms 6 | 445
Depressive disorder 6 | 409
Dull intelligence 6 | 645
Epilepsy 6 | 792
Hyperglycemia 6 | 137
Hypoplastic mandible condyle 6 | 275
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mandibular hypoplasia 6 | 275
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Micrognathism 6 | 275
Poor school performance 6 | 645
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
Bipolar Disorder 5 | 666
Broad flat nasal bridge 5 | 236
Cognitive delay 5 | 608
Delayed bone age 5 | 136
Duchenne muscular dystrophy 5 | 601
Fetal Growth Retardation 5 | 189
Global developmental delay 5 | 608
Hypertension 5 | 396
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Mental and motor retardation 5 | 608
Nasal bridge wide 5 | 236
Neoplasm Metastasis 5 | 168
Obesity 5 | 678
Polycystic ovary syndrome 5 | 360
Prostatic Neoplasms 5 | 495
Renal Cell Carcinoma 5 | 214
Rheumatoid arthritis 5 | 1,191
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
pancreatic carcinoma 5 | 562
Amyotrophic lateral sclerosis 4 | 451
Carcinoma, Hepatocellular 4 | 228
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Endometriosis 4 | 540
Failure to gain weight 4 | 365
Infantile onset 4 | 238
Liver carcinoma 4 | 240
Neurodegenerative disease 4 | 414
Neuropathy 4 | 261
Pediatric failure to thrive 4 | 365
Short stature 4 | 531
Small head 4 | 374
Stomach Neoplasms 4 | 300
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
pituitary cancer 4 | 1,972
progressive supranuclear palsy 4 | 676

Tissue

Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Skin and soft tissues 35 | 17,230
Endocrine System 34 | 18,159
Nervous System 34 | 16,725
Male tissues 33 | 17,142
Respiratory system 33 | 16,393
Urinary Tract 33 | 16,678
Blood and immune system 32 | 16,909
Cardiovascular System 31 | 15,192

Target Family

Kinase 13 | 634
Non-IDG 13 | 12,091
Enzyme 8 | 4,145
GPCR 2 | 408
Ion Channel 1 | 344

GO Process

phosphatidylinositol-mediated ... 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
G-protein coupled receptor 143 GPR143 Tbio GPCR -1.72669 53.7 93
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
GRB2-associated-binding protein 2 GAB2 Tbio Non-IDG -2.08460 139.8 494
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134
Mucin-5AC MUC5AC Tbio Non-IDG -3.22130 1630.6 458
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Phosphatidylinositol 4-kinase beta PI4KB Tchem Kinase -1.85524 71.3 104
Putative phosphatidylinositol 4-kinase alpha-like protein P2 PI4KAP2 Tdark Enzyme -1.08718 27.9 0