Development Level

Tbio 13 | 11,651
Tchem 3 | 1,388
Tclin 2 | 612
Tdark 2 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal gait 1 | 69
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased body weight 1 | 25

Disease

ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
osteosarcoma 11 | 7,950
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Bipolar Disorder 5 | 666
Pick disease 5 | 1,894
ductal carcinoma in situ 5 | 1,745
lung cancer 5 | 4,740
Astrocytoma, Pilocytic 4 | 3,081
Hypoplastic mandible condyle 4 | 275
Kidney cancer 4 | 2,613
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Schizophrenia 4 | 1,160
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Autosomal recessive predisposition 3 | 1,442
Cataract 3 | 297
Endometrial cancer 3 | 311
Frontal bossing 3 | 157
High forehead 3 | 102
Intellectual disability 3 | 1,016
Microstomia 3 | 78
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Tall forehead 3 | 102
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
hereditary spastic paraplegia 3 | 318
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
Amyotrophic lateral sclerosis 2 | 451
Big calvaria 2 | 147
Broad flat nasal bridge 2 | 236
Cancer 2 | 2,499
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
DOID:2627 2 | 94
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Endometriosis 2 | 540
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Fatigue 2 | 182
Fever 2 | 138
Global developmental delay 2 | 608
Hearing Loss, Partial 2 | 185
Hydrocephalus 2 | 152
Hyperkyphosis 2 | 111
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Kyphosis deformity of spine 2 | 114
Lens Opacities 2 | 231
Mental and motor retardation 2 | 608
Myopia 2 | 176
Nasal bridge wide 2 | 236
Orbital separation excessive 2 | 244
Pediatric failure to thrive 2 | 365
Polydactyly 2 | 107
Polymicrogyria 2 | 48
Syndactyly 2 | 88
Telecanthus 2 | 62
Ventricular Septal Defects 2 | 119
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
hearing impairment 2 | 199
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Enzyme 7 | 4,145
Kinase 7 | 634
Non-IDG 6 | 12,091

GO Process

phosphatidylinositol phosphory... 20 | 20
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inositol monophosphatase 3 IMPAD1 Tdark Enzyme -0.78606 4.97 79
Phosphatidylinositol 4-kinase type 2-alpha PI4K2A Tbio Kinase -2.88003 745.1 146
Inositol hexakisphosphate kinase 2 IP6K2 Tbio Kinase -1.39564 26.1 140
3'(2'),5'-bisphosphate nucleotidase 1 BPNT1 Tbio Enzyme -0.94366 8.13 165
Hyccin FAM126A Tbio Non-IDG -0.95309 9.49 51
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.51919 316.4 758
Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 Tbio Enzyme -1.80666 60.0 432
Inositol monophosphatase 2 IMPA2 Tbio Enzyme -1.49842 31.5 67
Inositol hexakisphosphate kinase 1 IP6K1 Tbio Kinase -1.49984 35.1 148
Tetratricopeptide repeat protein 7B TTC7B Tbio Non-IDG -0.38620 2.17 21