Development Level

Tbio 7 | 10,625
Tclin 3 | 602
Tchem 1 | 1,890

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal seminal vesicle morph... 1 | 47
enlarged heart 1 | 111
increased blood urea nitrogen ... 1 | 44
increased circulating triglyce... 1 | 24
persistence of hyaloid vascula... 1 | 22
tremors 1 | 34

Disease

psoriasis 7 | 6,685
glioblastoma 6 | 5,572
pilocytic astrocytoma 6 | 3,086
lung carcinoma 5 | 2,844
ovarian cancer 5 | 8,492
atypical teratoid / rhabdoid tumor 4 | 4,369
medulloblastoma, large-cell 4 | 6,234
osteosarcoma 4 | 7,933
Cancer 3 | 2,346
Carcinoma 3 | 2,147
Schizophrenia 3 | 503
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
invasive ductal carcinoma 3 | 2,950
lung cancer 3 | 4,473
primitive neuroectodermal tumor 3 | 3,031
subependymal giant cell astrocytoma 3 | 2,287
Basal Ganglia Diseases 2 | 12
Breast cancer 2 | 3,099
Epilepsy 2 | 346
Gastrointestinal stromal tumor 2 | 61
IGA Glomerulonephritis 2 | 454
Osteoporosis 2 | 259
Pain 2 | 70
Pancreatic Neuroendocrine Tumor 2 | 45
Parkinson's disease 2 | 364
Pick disease 2 | 1,893
Renal Cell Carcinoma 2 | 199
Rheumatoid Arthritis 2 | 1,171
Sarcoma of soft tissue 2 | 11
cystic fibrosis 2 | 1,670
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
group 3 medulloblastoma 2 | 2,254
head and neck cancer 2 | 270
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
interstitial cystitis 2 | 2,299
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
sonic hedgehog group medulloblastoma 2 | 1,482
ulcerative colitis 2 | 2,087
Aarskog-Scott syndrome 1 | 11
Agammaglobulinemia 1 | 24
Alexithymia 1 | 14
Allergic conjunctivitis 1 | 25
Angioedema 1 | 36
Anxiety 1 | 24
Anxiety disorder 1 | 22
Basal Ganglia Calcification, Idiopathic, 1 1 | 5
Basal ganglia calcification 1 | 17
Blastic phase chronic myeloid leukemia 1 | 58
Brain cancer 1 | 24
Centronuclear myopathy 1 | 21
Chromosome 1p36 deletion syndrome 1 | 24
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic eosinophilic leukemia 1 | 11
Chronic phase chronic myeloid leukemia 1 | 45
Chronic schizophrenia 1 | 4
Cocaine dependence 1 | 24
Cognition Disorders 1 | 23
Conduct disorder 1 | 25
Cone-Rod Dystrophy 5 1 | 2
Dermatofibrosarcoma protuberans 1 | 16
Dyskinetic syndrome 1 | 6
Eating disorder 1 | 24
General anesthesia 1 | 53
Gilles de la Tourette's syndrome 1 | 3
Hamman-Rich syndrome 1 | 35
Hyperprolactinemia 1 | 22
Hypotension 1 | 53
Idiopathic hypereosinophilic syndrome 1 | 10
Kindler syndrome 1 | 10
Language Disorders 1 | 2
Leukemia, acute myelogenous 1 | 8
Leukemia, juvenile myelomonocytic 1 | 7
Malignant histiocytosis 1 | 2
Memory Disorders 1 | 36
Mixed anxiety and depressive disorder 1 | 10
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 1 | 9
Myoclonic dystonia 1 | 3
Nasal discharge 1 | 26
Nausea 1 | 9
Nausea and vomiting 1 | 6
Oculocerebrorenal syndrome 1 | 24
Parkinsonian Disorders 1 | 23
Pertussis 1 | 17
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pituitary Neoplasms 1 | 6
Postencephalitic parkinsonism 1 | 12
Pre-Op Apprehension 1 | 10
Sneezing 1 | 11
Stuttering 1 | 18
Substance abuse 1 | 55
Systemic mast cell disease 1 | 12
Tetanus Adjunct Treatment 1 | 8
Tobacco Use Disorder 1 | 10
Type 2 Diabetes Mellitus Treatment Adjunct 1 | 7

Tissue

Blood and immune system 11 | 17,995
Cardiovascular System 11 | 17,958
Digestive Tract 11 | 18,473
Endocrine System 11 | 18,512
Female tissues 11 | 18,647
Liver and Pancreas 11 | 18,136
Male tissues 11 | 17,969
Nervous System 11 | 18,561
Respiratory system 11 | 17,484
Skin and soft tissues 11 | 18,115
Urinary Tract 11 | 18,444

Target Family

Enzyme 3 | 4,146
Kinase 3 | 634
Non-IDG 3 | 11,969
GPCR 2 | 408

GO Process

phosphatidylinositol metabolic... 11 | 11
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 PLCD4 Tbio Enzyme -1.08516 11.1 38
Galanin receptor type 2 GALR2 Tchem GPCR -1.88843 67.4 195
Membrane-associated phosphatidylinositol transfer protein 3 PITPNM3 Tbio Non-IDG -1.33078 20.4 103
Inositol hexakisphosphate kinase 3 IP6K3 Tbio Kinase -0.32056 2.93 93
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 PLCH2 Tbio Enzyme -0.80082 6.80 5
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.74048 58.0 91
D(2) dopamine receptor DRD2 Tclin GPCR -3.26127 1775.2 248
Pleckstrin PLEK Tbio Non-IDG -2.99140 713.7 264
Platelet-derived growth factor receptor beta PDGFRB Tclin Kinase -2.86534 653.9 1172
Macrophage colony-stimulating factor 1 receptor CSF1R Tclin Kinase -3.16364 1355.8 962