Development Level

Tbio 18 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 21 | 11,493
ovarian cancer 13 | 8,520
medulloblastoma, large-cell 12 | 6,241
ependymoma 11 | 4,679
osteosarcoma 11 | 7,950
lung cancer 10 | 4,740
Oculocerebrorenal syndrome 9 | 29
adult high grade glioma 8 | 3,801
Kidney cancer 7 | 2,613
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
psoriasis 7 | 6,694
Pick disease 6 | 1,894
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
Acquired scoliosis 5 | 281
Centronuclear myopathy 5 | 27
Curvature of spine 5 | 282
Intellectual disability 5 | 1,016
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Epilepsy 4 | 792
Seizures 4 | 596
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
lung adenocarcinoma 4 | 2,716
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Big calvaria 3 | 147
Cataract 3 | 297
Charcot-Marie-Tooth disease 3 | 62
Cryptorchidism 3 | 296
Dull intelligence 3 | 645
Frontal bossing 3 | 157
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Parkinson's disease 3 | 392
Poor school performance 3 | 645
active Crohn's disease 3 | 922
colon cancer 3 | 1,478
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Bell Palsy 2 | 58
Breast Neoplasms 2 | 445
Byzanthine arch palate 2 | 194
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dermatologic disorders 2 | 93
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Hypertension 2 | 396
Impaired cognition 2 | 96
Long narrow head 2 | 75
Long philtrum 2 | 137
Lymphedema 2 | 42
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Mental impairment 2 | 95
Myopathy 2 | 185
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Polyhydramnios 2 | 108
Range of joint movement increased 2 | 32
Reflex, Deep Tendon, Absent 2 | 92
Reperfusion Injury 2 | 86
Respiratory Failure 2 | 104
Short nose 2 | 132
Skin cancer 2 | 469
Small nose 2 | 132
Turridolichocephaly 2 | 75
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Enzyme 20 | 4,145
Non-IDG 2 | 12,091

GO Process

phosphatidylinositol dephospho... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Myotubularin-related protein 1 MTMR1 Tbio Enzyme -0.89579 6.93 82
Synaptojanin-2 SYNJ2 Tbio Non-IDG -1.15573 16.3 157
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Type II inositol 1,4,5-trisphosphate 5-phosphatase INPP5B Tbio Enzyme -1.53163 29.3 109
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.05056 144.2 215
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 INPP5D Tbio Enzyme -2.06945 104.7 374
Phosphatidylinositide phosphatase SAC1 SACM1L Tbio Enzyme -2.04383 109.7 89
Phosphatidylinositide phosphatase SAC2 INPP5F Tbio Enzyme -0.71120 5.56 89
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126