Development Level

Tbio 49 | 11,445
Tchem 21 | 1,598
Tclin 3 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Target... 6 | 125
RFA-RM-18-021 6 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
decreased body weight 3 | 161
embryonic lethality prior to t... 3 | 278
abnormal epididymis morphology 2 | 42
abnormal sleep behavior 2 | 70
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
edema 2 | 59
embryonic growth retardation 2 | 106
enlarged epididymis 2 | 31
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
persistence of hyaloid vascula... 2 | 33
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
polydactyly 1 | 7
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 63 | 11,493
ovarian cancer 46 | 8,520
medulloblastoma, large-cell 41 | 6,241
osteosarcoma 40 | 7,950
glioblastoma 33 | 5,792
atypical teratoid / rhabdoid tumor 31 | 5,112
ependymoma 28 | 4,679
adult high grade glioma 25 | 3,801
psoriasis 25 | 6,694
lung cancer 24 | 4,740
Kidney cancer 23 | 2,613
group 3 medulloblastoma 19 | 4,104
oligodendroglioma 19 | 2,850
Astrocytoma, Pilocytic 17 | 3,081
astrocytic glioma 17 | 2,597
primitive neuroectodermal tumor 16 | 3,035
Breast cancer 15 | 3,578
Cancer 15 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
subependymal giant cell astrocytoma 15 | 2,287
invasive ductal carcinoma 14 | 2,951
malignant mesothelioma 13 | 3,232
Pick disease 12 | 1,894
diabetes mellitus 12 | 1,728
lung carcinoma 12 | 2,843
ulcerative colitis 12 | 1,819
Centronuclear myopathy 11 | 27
Schizophrenia 11 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
Autosomal recessive predisposition 10 | 1,442
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
Oculocerebrorenal syndrome 9 | 29
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
juvenile dermatomyositis 9 | 1,187
pituitary cancer 9 | 1,972
tuberculosis 9 | 2,010
Intellectual disability 8 | 1,016
Seizures 8 | 596
spina bifida 8 | 1,074
Acquired scoliosis 7 | 281
Curvature of spine 7 | 282
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
primary Sjogren syndrome 7 | 735
Cataract 6 | 297
Epilepsy 6 | 792
Frontal bossing 6 | 157
Multiple myeloma 6 | 1,332
Neurodegenerative disease 6 | 414
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
gastric carcinoma 6 | 807
Absent reflex 5 | 92
Absent tendon reflex 5 | 92
Big calvaria 5 | 147
Bipolar Disorder 5 | 666
Charcot-Marie-Tooth disease 5 | 62
DOID:2627 5 | 94
Hypoplastic mandible condyle 5 | 275
Increased head circumference 5 | 147
Increased size of cranium 5 | 147
Increased size of skull 5 | 147
Lens Opacities 5 | 231
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Muscle hypotonia 5 | 571
Neuropathy 5 | 261
Orbital separation excessive 5 | 244
Reflex, Deep Tendon, Absent 5 | 92
active Crohn's disease 5 | 922
aldosterone-producing adenoma 5 | 665
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
pancreatic carcinoma 5 | 562
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Depressive disorder 4 | 409
Endometrial cancer 4 | 311
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Parkinson's disease 4 | 392
Polymicrogyria 4 | 48
Progressive disorder 4 | 142
Prostatic Neoplasms 4 | 495
Vascular disease 4 | 319
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
progressive supranuclear palsy 4 | 676

Tissue

Blood and immune system 76 | 16,909
Digestive Tract 76 | 17,369
Endocrine System 76 | 18,159
Female tissues 76 | 17,400
Male tissues 76 | 17,142
Nervous System 76 | 16,725
Liver and Pancreas 75 | 16,750
Respiratory system 75 | 16,393
Skin and soft tissues 75 | 17,230
Urinary Tract 75 | 16,678
Cardiovascular System 74 | 15,192

Target Family

Enzyme 37 | 4,145
Kinase 21 | 634
Non-IDG 17 | 12,091
Transporter 1 | 473

GO Process

phosphatidylinositol biosynthe... 76 | 76
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Myotubularin-related protein 1 MTMR1 Tbio Enzyme -0.89579 6.93 82
Type I inositol 3,4-bisphosphate 4-phosphatase INPP4A Tbio Enzyme -1.12941 13.9 47
Membrane-associated phosphatidylinositol transfer protein 3 PITPNM3 Tbio Non-IDG -1.39360 23.8 107
Membrane-associated phosphatidylinositol transfer protein 2 PITPNM2 Tdark Non-IDG -0.73640 4.35 66
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
Myotubularin-related protein 4 MTMR4 Tbio Enzyme -0.76288 7.50 138
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.47825 30.5 103
Synaptojanin-2 SYNJ2 Tbio Non-IDG -1.15573 16.3 157