Development Level

Tbio 7 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased blood urea nitrogen ... 1 | 51
decreased cardiac muscle contr... 1 | 11
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
enlarged heart 1 | 210
enlarged kidney 1 | 14
increased circulating alkaline... 1 | 122
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
small testis 1 | 58

Disease

Carcinoma 7 | 11,493
Atherosclerosis 6 | 291
Coronary artery disease 6 | 268
Obesity 5 | 678
diabetes mellitus 5 | 1,728
osteosarcoma 5 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Hypercholesterolemia, Familial 4 | 23
Lipid metabolism disorder 4 | 114
lung cancer 4 | 4,740
Cardiovascular system disease 3 | 246
Cerebrovascular disease 3 | 238
Hyperlipoproteinemia Type II 3 | 12
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
non-small cell lung cancer 3 | 2,890
ovarian cancer 3 | 8,520
Abnormality of metabolism/homeostasis 2 | 134
Abnormality of the antitragus 2 | 5
Anxiety 2 | 136
Anxiety disease 2 | 113
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Babinski Reflex 2 | 100
Bipolar Disorder 2 | 666
Cardiovascular Diseases 2 | 59
Cerebellar Ataxia 2 | 304
Constipation 2 | 181
Cryptorchidism 2 | 296
Depressive disorder 2 | 409
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Gait abnormality 2 | 135
Hypercholesterolemia 2 | 44
Hyperlipoproteinemias 2 | 5
Hyperreflexia 2 | 209
Hypertension 2 | 396
Hypertriglyceridemia 2 | 17
Intellectual disability 2 | 1,016
Kidney Failure 2 | 111
Kidney disease 2 | 430
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Metabolic syndrome X 2 | 52
Muscle Spasticity 2 | 195
Muscle hypotonia 2 | 571
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Pediatric Obesity 2 | 4
Poor school performance 2 | 645
Progressive disorder 2 | 142
Proteinuria 2 | 144
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Short stature 2 | 531
Skeletal muscle atrophy 2 | 139
Speech Disorders 2 | 58
Toxic encephalopathy 2 | 141
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
muscle degeneration 2 | 139
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
Atony of facial musculature 1 | 3
Atypical autism 1 | 26
Coronary Artery Vasospasm 1 | 6
Coronary Vasospasm 1 | 3
Distal lower limb muscle weakness 1 | 6
Dysphasia 1 | 23
Facial hypotonia 1 | 3
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Gait, Shuffling 1 | 8
Gordon Holmes Syndrome 1 | 2
Hand deformities 1 | 32
Hematologic Neoplasms 1 | 22
Hypotriglyceridaemia 1 | 3
Isolated somatotropin deficiency 1 | 30
Learning Disorders 1 | 29
Macroorchidism 1 | 7
Micronuclei, Chromosome-Defective 1 | 25
Neurodegeneration with brain iron accumulation 1 | 20
Neurotoxicity Syndromes 1 | 26
Occupational Diseases 1 | 12
Parkinson Disease, Secondary 1 | 9
Peripheral Nervous System Diseases 1 | 52
Progressive spastic paraplegia 1 | 2
Rett syndrome 1 | 18
Secondary Parkinson Disease 1 | 10
Xerostomia 1 | 42

Tissue

Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Skin and soft tissues 10 | 17,230
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Nervous System 8 | 16,725
Cardiovascular System 7 | 15,192

Target Family

Enzyme 6 | 4,145
Non-IDG 3 | 12,091
Transcription Factor 1 | 1,400

GO Process

phosphatidylcholine metabolic ... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phospholipase ABHD3 ABHD3 Tbio Enzyme -0.41218 2.23 91
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Neuropathy target esterase PNPLA6 Tbio Enzyme -2.67941 466.8 159
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
Phosphatidylcholine-sterol acyltransferase LCAT Tbio Enzyme -2.52851 336.6 270
Phosphatidylinositol-glycan-specific phospholipase D GPLD1 Tbio Enzyme -2.08209 126.8 222
Serum paraoxonase/arylesterase 1 PON1 Tbio Enzyme -3.39345 2648.8 361
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.26513 1878.2 658
Phospholipase A2 PLA2G1B Tchem Enzyme -3.17567 1113.8 211
Apolipoprotein A-IV APOA4 Tbio Non-IDG -2.45218 211.8 324