Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
decreased blood urea nitrogen ... 1 | 51
decreased erythrocyte cell num... 1 | 62
embryonic lethality prior to o... 1 | 239
increased body weight 1 | 25
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
ovarian cancer 10 | 8,520
osteosarcoma 9 | 7,950
Breast cancer 8 | 3,578
Cancer 8 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
lung cancer 7 | 4,740
malignant mesothelioma 7 | 3,232
Cleft Palate 6 | 271
Craniofacial Abnormalities 6 | 151
invasive ductal carcinoma 6 | 2,951
psoriasis 6 | 6,694
Congenital heart disease 5 | 93
adult high grade glioma 5 | 3,801
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
Acquired scoliosis 4 | 281
Astrocytoma, Pilocytic 4 | 3,081
Cleft uvula 4 | 27
Cognitive delay 4 | 608
Conductive hearing loss 4 | 123
Curvature of spine 4 | 282
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Preauricular Fistulae, Congenital 4 | 27
Preauricular dimple 4 | 27
Preauricular sinus 4 | 27
RENAL ADYSPLASIA 4 | 25
Renal dysplasia 4 | 28
Sensorineural Hearing Loss (disorder) 4 | 284
Umbilical hernia 4 | 93
Uranostaphyloschisis 4 | 167
Velocardiofacial syndrome 4 | 46
Ventricular Septal Defects 4 | 119
group 3 medulloblastoma 4 | 4,104
pancreatic cancer 4 | 2,398
Bilateral fifth finger clinodactyly 3 | 110
Bipolar Disorder 3 | 666
Byzanthine arch palate 3 | 194
Congenital Heart Defects 3 | 58
Congenital deafness 3 | 185
Congenital hypoplasia of penis 3 | 176
Conotruncal Heart Malformations 3 | 10
Constipation 3 | 181
Curvature of little finger 3 | 110
Deafness 3 | 198
DiGeorge syndrome 3 | 47
Dull intelligence 3 | 645
Dyschezia 3 | 135
Hearing Loss, Partial 3 | 185
Heart Defects, Congenital 3 | 37
Heart disease 3 | 306
Highly variable severity 3 | 157
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Long face 3 | 71
Low intelligence 3 | 645
Low set ears 3 | 181
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Narrow face 3 | 54
Orbital separation excessive 3 | 244
Patent ductus arteriosus 3 | 90
Poor school performance 3 | 645
Renal agenesis 3 | 29
Schizophrenia 3 | 1,160
Short stature 3 | 531
Tetralogy of Fallot 3 | 63
Thin face 3 | 54
Variable expressivity 3 | 157
Vesico-Ureteral Reflux 3 | 33
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
hearing impairment 3 | 199
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
sonic hedgehog group medulloblastoma 3 | 467
Abnormality of metabolism/homeostasis 2 | 134
Alobar Holoprosencephaly 2 | 14
Atrial Septal Defects 2 | 85
Capuchin ears 2 | 17
Cupped ears (finding) 2 | 17
Downward slant of palpebral fissure 2 | 158
Holoprosencephaly 2 | 56
Hypotrophic malar bone 2 | 129
Malar flattening 2 | 129
Malformed pinnae 2 | 37
Myocardial Infarction 2 | 151
Nonsyndromic deafness 2 | 142
Osteoporosis 2 | 363
Retrognathia 2 | 54
Semilobar Holoprosencephaly 2 | 14

Tissue

Blood and immune system 16 | 16,909
Female tissues 16 | 17,400
Male tissues 16 | 17,142
Urinary Tract 16 | 16,678
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Liver and Pancreas 15 | 16,750
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Cardiovascular System 14 | 15,192
Nervous System 14 | 16,725

Target Family

Transcription Factor 8 | 1,400
Non-IDG 7 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145

GO Process

pharyngeal system development 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Homeobox protein Nkx-2.6 NKX2-6 Tbio Transcription Factor -3.04651 1092.2 134
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Protein ripply3 RIPPLY3 Tdark Non-IDG -0.63009 3.97 10
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Bone morphogenetic protein 5 BMP5 Tbio Non-IDG -1.93094 81.4 344
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385