Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
anophthalmia 1 | 33
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating potassiu... 1 | 20
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
hypoactivity 1 | 132
increased cardiac muscle contr... 1 | 8
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56

Disease

Carcinoma 6 | 11,493
ovarian cancer 5 | 8,520
glioblastoma 4 | 5,792
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Emphysema 2 | 12
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Pathological accumulation of air in tissues 2 | 10
Pick disease 2 | 1,894
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormal ocular motility 1 | 19
Acquired metabolic disease 1 | 336
Anteverted nostril 1 | 191
Anxiety 1 | 136
Anxiety disease 1 | 113
Ataxia, Spinocerebellar 1 | 16
Atopic dermatitis 1 | 952
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
COPD 1 | 118
Cerebellar Dysmetria 1 | 56
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Degenerative polyarthritis 1 | 115
Delayed myelination 1 | 22
Delusions 1 | 11
Dementia 1 | 175
Depressive disorder 1 | 409
Dilated ventricles (finding) 1 | 121
Disease Progression 1 | 136
Downward slant of palpebral fissure 1 | 158
Dysarthria 1 | 192
Dysdiadochokinesis 1 | 25
Endometrial cancer 1 | 311
Endometriosis 1 | 540
Epilepsy 1 | 792
Essential tremor 1 | 28
Friedreich ataxia 1 | 24
Gross motor development delay 1 | 21
Hyperreflexia 1 | 209
Hypoplasia of corpus callosum 1 | 90
Infratentorial atrophy 1 | 103
Inverted V-shaped upper lip 1 | 19
Machado-Joseph disease 1 | 18
Nephrotic Syndrome 1 | 78
Neurodegenerative disease 1 | 414
Open mouth 1 | 45
Osteoarthritis 1 | 184
Parkinsonian Disorders 1 | 56
Pectus excavatum 1 | 100
Peripheral sensorimotor neuropathy 1 | 16
Proteinuria 1 | 144
Range of joint movement increased 1 | 32
Seizures 1 | 596
Spinocerebellar Ataxias 1 | 34
Spinocerebellar ataxia type 1 1 | 16
Spinocerebellar ataxia type 8 1 | 7
Stomach Neoplasms 1 | 300
Tented mouth 1 | 19
Tented upper lip 1 | 19
Type 2 diabetes mellitus 1 | 272
Vaccinia 1 | 36
Wolcott-Rallison syndrome 1 | 10
active Crohn's disease 1 | 922
aldosterone-producing adenoma 1 | 665
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
dentatorubral-pallidoluysian atrophy 1 | 21
interstitial lung disease 1 | 298
lung adenocarcinoma 1 | 2,716
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
spina bifida 1 | 1,074
substance-related disorder 1 | 162
tuberculosis and treatment for 6 months 1 | 409
type I diabetes mellitus 1 | 22

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Enzyme 7 | 4,145
Non-IDG 1 | 12,091

GO Process

peptidyl-serine dephosphorylat... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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