Development Level

Tchem 4 | 1,598
Tbio 1 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal gait 1 | 69
decreased body weight 1 | 161
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
increased heart weight 1 | 62

Disease

Carcinoma 5 | 11,493
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Cancer 3 | 2,499
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
Adenoid Cystic Carcinoma 2 | 99
Carcinoma, Adenoid Cystic 2 | 99
Epilepsy 2 | 792
Kidney cancer 2 | 2,613
Melanoma 2 | 711
Neurodegenerative disease 2 | 414
Nystagmus 2 | 317
Schizophrenia 2 | 1,160
Short stature 2 | 531
Strabismus 2 | 270
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Abnormal helices 1 | 11
Abnormality of the ulna 1 | 10
Absent eyebrow 1 | 13
Agenesis of eyebrows 1 | 13
Anorexia 1 | 43
Aplasia of eyebrows 1 | 13
Ataxia telangiectasia 1 | 34
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
B-Cell Lymphomas 1 | 12
Birthmark 1 | 35
Bloom syndrome 1 | 29
Bone Marrow Diseases 1 | 7
Brittle hair 1 | 25
Bronchiectasis 1 | 64
Cafe au lait spots, multiple 1 | 17
Cafe-au-Lait Spots 1 | 37
Cardio-facio-cutaneous syndrome 1 | 6
Cardiofaciocutaneous syndrome 1 | 15
Cardiofaciocutaneous syndrome 1 1 | 4
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Chromosome Breakage 1 | 36
Costello Syndrome 1 | 17
Costello syndrome (disorder) 1 | 6
DOID:9917 1 | 31
Deep palmar crease 1 | 8
Delayed Puberty 1 | 97
Depressed cheekbone 1 | 22
Dystrophic fingernails 1 | 18
Excessive wrinkled skin 1 | 16
Female hypogonadism syndrome 1 | 25
Fine hair 1 | 42
Flattening of the zygomatic bone 1 | 22
Fractured hair 1 | 25
Fragile hair 1 | 25
Generalized hyperpigmentation 1 | 22
Hair hypopigmentation 1 | 12
Hematologic Neoplasms 1 | 22
Hypoplasia of the zygomatic bone 1 | 22
Hypotrophic cheekbone 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Increased chromosomal breakage 1 | 27
Intolerant of heat 1 | 7
LEOPARD syndrome 1 | 20
Long palpebral fissure 1 | 17
Lymphoma, T-Cell, Cutaneous 1 | 22
Lymphoma, T-Cell, Peripheral 1 | 9
Madarosis of eyebrow 1 | 13
Malignant Melanoma with BRAF V600E Mutation 1 | 4
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 1 | 12
Metastatic malignant melanoma 1 | 9
Mucosal telangiectasiae 1 | 14
Multiple lentigines 1 | 10
Neoplasms 1 | 63
Noonan syndrome 1 | 34
Paranasal Sinus Diseases 1 | 34
Partial to total absence of eyelashes 1 | 7
Premature canities 1 | 24
Pulmonary Stenosis 1 | 45
Recurrent bronchitis 1 | 23
Reduced tensile strength of hair 1 | 25
Secretory diarrhea 1 | 10
Senile lentigo 1 | 10
Sinusitis 1 | 65
Slow-growing hair 1 | 19
Small cheekbone 1 | 22
Small thymus 1 | 13
Sparse or absent eyelashes 1 | 7
Sparse to absent eyelashes 1 | 7
Sternal anomalies 1 | 19
Susceptibility to viral and mycobacterial infections 1 | 11
Thickened helices 1 | 15
Ventricular Dysfunction, Left 1 | 22
Werner syndrome 1 | 29
Xeroderma pigmentosum 1 | 43

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Kinase 6 | 634

GO Process

peptidyl-serine autophosphoryl... 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
cGMP-dependent protein kinase 2 PRKG2 Tchem Kinase -1.74379 54.2 169
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.83744 60.9 883
Serine-protein kinase ATM ATM Tchem Kinase -3.57054 3681.6 1024
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1 Tchem Kinase -2.44644 224.3 489